Constitutive Activity in Receptors and Other Proteins, Part A, Volume 484

1st Edition

Serial Volume Editors: Melvin Simon
Hardcover ISBN: 9780123812988
eBook ISBN: 9780123812995
Imprint: Academic Press
Published Date: 11th November 2010
Page Count: 804
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Table of Contents

Section I-- Identification and Measurement of Constitutive Activity

  1. Constitutive activity at the cannabinoid CB1 receptor and behavioral responses
  2. Katherine E. Hanlon and Todd W. Vanderah

  3. Detecting constitutive activity and protean agonism at the cannabinoid-2 receptor.
  4. Massimiliano Beltramo, Rossella Brusa, Isabella Mancini, Paola Scandroglio, Massimiliano. Beltramo

  5. Modulation of constitutive activity of the ghrelin receptor by use of pharmacological tools as well as mutagenesis
  6. Birgitte Holst and Jacek Mokrosiński

  7. Assessment of constitutive activity and internalization of GPR54 (Kiss1-r).
  8. Macarena Pampillo and Andy Videsh Babwah

  9. Assessment of Constitutive Activity in EP Prostanoid Receptors
  10. Hiromichi Fujino, Toshihiko Murayama, and John W. Regan

  11. α1D-Adrenergic receptors: constitutive activity and reduced expression at the plasma membrane
  12. J Adolfo Garcia-Sáinz, M. Teresa Romero-Ávila and Luz del Carmen Medina

  13. Constitutive activity of the histamine H1 receptor
  14. Saskia Nijmeijer, Rob Leurs and Henry F Vischer

  15. Constitutive activity of somatostatin receptor subtypes
  16. Anat Ben-Shlomo, Kolja Wawrowsky and Shlomo Melmed

  17. Assessment of homologous internalization of constitutively active N111G mutant of AT1 receptor
  18. Mohiuddin Ahmed Bhuiyan and Takafumi Nagatomo

  19. Methods to detect cell surface expression and constitutive activity of GPR6
  20. Balakrishna M. Prasad, Bettye Hollins and Nevin A. Lambert

  21. β3-adrenoceptor agonists and (antagonists as) inverse agonists: history, perspective, constitutive activity and stereospecific binding.
  22. Maria Grazia Perrone and Antonio Sc


Description

This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.

Key Features

A. Expert authors who are leaders in the field

B. Extensively referenced and useful figures and tables

C. Provides hints and tricks to facilitate reproduction of methods

Readership

Researchers and students in cell, molecular and developmental biology


Details

No. of pages:
804
Language:
English
Copyright:
© Academic Press 2010
Published:
Imprint:
Academic Press
eBook ISBN:
9780123812995
Hardcover ISBN:
9780123812988

About the Serial Volume Editors

Melvin Simon Serial Volume Editor

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA