Conjugates of Steroid Hormones

Conjugates of Steroid Hormones

1st Edition - January 1, 1969

Write a review

  • Authors: Harry E. Hadd, Robert T. Blickenstaff
  • eBook ISBN: 9781483263458

Purchase options

Purchase options
DRM-free (PDF)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Conjugates of Steroid Hormones focuses on the synthesis, isolation, assay, and metabolism of steroid conjugates. The book first offers information on the isolation of steroid conjugates and sulfates of steroid hormones. Topics include separation of steroid conjugates by adsorption, isolation from natural sources, group separation of sulfates and glucuronides, enzymic synthesis, and separation of steroid conjugates by solvent extraction. The manuscript then tackles glucuronides and glycosides of steroid hormones, as well as chemical synthesis and biosynthesis of diconjugates. The text ponders on phosphates of steroid hormones and metabolism of steroid conjugates. Discussions focus on the occurrence of steroid phosphates in biological fluids; metabolism of dehydroepiandrosterone sulfate to estrogens; formation of dehydroepiandrosterone sulfate; and estrogen conjugates. The publication is highly recommended for organic chemists and biochemists.

Table of Contents


  • Contents

    Foreword

    Preface

    Trivial and Systematic Names of Steroids

    ChapteR I. Isolation of Steroid Conjugates

    Isolation from Natural Sources

    Separation of the Steroid Conjugates by Solvent Extraction

    Separation of the Steroid Conjugates by Adsorption

    Group Separation of Sulfates and Glucuronides

    Separation of Individual Steroid Conjugates in Each Group

    References

    Chapter II. Sulfates of Steroid Hormones

    Enzymic Synthesis

    Chemical Synthesis

    Synthesis of Radioactive Sulfates

    Explanation of Table II.2

    References

    Table II.2

    Chapter III. Glucuronides of Steroid Hormones

    Enzymic Glucuronylations

    Chemical Synthesis

    Explanation of Table III.3

    References

    Table III.3

    Chapter IV. Other Glycosides of Steroid Hormones

    Biosynthesis of Diconjugates

    Chemical Synthesis

    Explanation of Table IV.1

    References

    Table IV.1

    Chapter V. Phosphates of Steroid Hormones

    The Occurrence of Steroid Phosphates in Biological Fluids

    Chemical Synthesis of Steroid Phosphates

    Explanation of Table V.1

    References

    Table V.l

    Chapter VI. Metabolism of Steroid Conjugates

    Formation of Dehydroepiandrosterone Sulfate

    Metabolism of Dehydroepiandrosterone Sulfate to Estrogens

    Estrogen Conjugates

    A Unified Hypothesis Concerning the Biogenesis of the Glucuronide-Sulfate Conjugated Pairs of Androsterone and Etiocholanolone

    Testosterone Sulfate

    Sulfates in the Pregnane Series

    Tentative Structures

    Artifacts

    References

    Appendix I. A Proposed System of Nomenclature for Steroid Glycosides

    Appendix II. Nomenclature for Phosphorus Compounds

    Appendix III. Fortran IV Source List

    Author Index

    Subject Index

Product details

  • No. of pages: 384
  • Language: English
  • Copyright: © Academic Press 1969
  • Published: January 1, 1969
  • Imprint: Academic Press
  • eBook ISBN: 9781483263458

About the Authors

Harry E. Hadd

Robert T. Blickenstaff

Ratings and Reviews

Write a review

There are currently no reviews for "Conjugates of Steroid Hormones"