Concepts and Techniques in Genomics and Proteomics

1st Edition

Authors: N Saraswathy P Ramalingam
Hardcover ISBN: 9781907568107
eBook ISBN: 9781908818058
Imprint: Woodhead Publishing
Published Date: 1st July 2011
Page Count: 268
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Table of Contents

List of figures

List of tables



List of abbreviations

About the authors

Chapter 1: Introduction to genes and genomes


1.1 Introduction

1.2 The cell

1.3 Mendel’s contributions

1.4 The chromosomal theory of inheritance

1.5 The chemical nature of genetic material

1.6 Composition and structure of DNA

1.7 The central dogma of life

1.8 Genomes of prokaryotes and eukaryotes

1.9 The molecular structure of the gene

1.10 Conclusion

Review questions and answers

Web addresses

Chapter 2: The human genome project


2.1 The history of the HGP

2.2 The budget for the HGP

2.3 Goals of the HGP

2.4 Laboratories and investigators involved in the HGP

2.5 The Human Genome Organization (HUGO)

2.6 Salient findings of the HGP

2.7 Potential applications of the HGP

2.8 Post-HGP challenges

2.9 Ethical, legal, social issues (ELSI) related to the HGP

2.10 The international HapMap Project

Review questions and answers

Web addresses

Chapter 3: Genomes of model organisms


3.1 Introduction

3.2 The viral genome

3.3 Bacterial genomes

3.4 Fungal genomes

3.5 Worm genome: Caenorhabditis elegans

3.6 Fruit fly: Drosophila melanogaster

3.7 Plant genome

3.8 Animal genome

3.9 The Microbial Genome Project

Chapter 4: High capacity vectors


4.1 Introduction

4.2 Cosmid vectors

4.3 Fosmid vectors

4.4 Bacteriophage P1 derived vector

4.5 P1 derived artificial chromosome (PAC)

4.6 Bacterial artificial chromosomes (BAC)

4.7 Yeast artificial chromosome (YAC)

Review questions and answers

Web address

Chapter 5: DN


Concepts and techniques in genomics and proteomics covers the important concepts of high-throughput modern techniques used in the genomics and proteomics field. Each technique is explained with its underlying concepts, and simple line diagrams and flow charts are included to aid understanding and memory. A summary of key points precedes each chapter within the book, followed by detailed description in the subsections. Each subsection concludes with suggested relevant original references.

Key Features

  • Provides definitions for key concepts
  • Case studies are included to illustrate ideas
  • Important points to remember are noted


Undergraduate and post graduate students within biotechnology; Academics and researchers in other fields, such as life sciences, microbiology, biochemistry, medicine and bioinformatics


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Woodhead Publishing
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About the Authors

N Saraswathy Author

Dr Nachimuthu Saraswathy is currently Associate Professor at the Department of Biotechnology, Kumaraguru College of Technology. She teaches courses on Molecular Biology, Genetic Engineering, and Plant Biotechnology, as well as Genomics and Proteomics. Dr Saraswathy gained her Ph.D. in Molecular Biology from the National Centre for Plant Biotechnology, New Delhi. She has published several articles in journals of biotechnology and biochemistry.

P Ramalingam Author

Mr Ponnusamy Ramalingam is Associate Professor at the Department of Biotechnology, Kumaraguru College of Technology. He received his M.Sc. In Biochemistry from Gulbarga University and Mtech in Biotechnology from Anna University. He has also taught and researched in institutions such as Kongu Engineering College and PNC&KR College, and has contributed several published journal articles.

Affiliations and Expertise

Kumaraguru College of Technology, India