Description

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System reviews how a wide range of materials are modelled and how this modelling is applied. Computational modelling is increasingly important in the design and manufacture of biomedical materials, as it makes it possible to predict certain implant-tissue reactions, degradation, and wear, and allows more accurate tailoring of materials' properties for the in vivo environment.

Part I introduces generic modelling of biomechanics and biotribology with a chapter on the fundamentals of computational modelling of biomechanics in the musculoskeletal system, and a further chapter on finite element modelling in the musculoskeletal system. Chapters in Part II focus on computational modelling of musculoskeletal cells and tissues, including cell mechanics, soft tissues and ligaments, muscle biomechanics, articular cartilage, bone and bone remodelling, and fracture processes in bones. Part III highlights computational modelling of orthopedic biomaterials and interfaces, including fatigue of bone cement, fracture processes in orthopedic implants, and cementless cup fixation in total hip arthroplasty (THA). Finally, chapters in Part IV discuss applications of computational modelling for joint replacements and tissue scaffolds, specifically hip implants, knee implants, and spinal implants; and computer aided design and finite element modelling of bone tissue scaffolds.

This book is a comprehensive resource for professionals in the biomedical market, materials scientists and mechanical engineers, and those in academia.

Key Features

  • Covers generic modelling of cells and tissues; modelling of biomaterials and interfaces; biomechanics and biotribology
  • Discusses applications of modelling for joint replacements and applications of computational modelling in tissue engineering

Readership

Computational modelling of biomechanics and biotribology in the musculoskeletal system is a comprehensive resource for professionals in the biomedical market, materials scientists and mechanical engineers, and those in academia.

Table of Contents

  • Contributor contact details
  • Woodhead Publishing Series in Biomaterials
  • Foreword
  • Preface
  • Part I: Generic modelling of biomechanics and biotribology
    • 1. Fundamentals of computational modelling of biomechanics in the musculoskeletal system
      • Abstract:
      • 1.1 Computational approach and its importance
      • 1.2 Generic computational approach and important considerations
      • 1.3 Computational methods and software
      • 1.4 Future trends
      • 1.5 Sources of further information and advice
      • 1.6 References
    • 2. Finite element modeling in the musculoskeletal system: generic overview
      • Abstract:
      • 2.1 The musculoskeletal (MSK) system
      • 2.2 Overview of the finite element (FE) method
      • 2.3 State-of-the-art FE modeling of the MSK system
      • 2.4 Key modeling procedures and considerations
      • 2.5 Challenges and future trends
      • 2.6 References
    • 3. Joint wear simulation
      • Abstract:
      • 3.1 Introduction
      • 3.2 Classification of wear
      • 3.3 Analytic and theoretical modelling of wear
      • 3.4 Implementation of wear modelling in the assessment of joint replacement
      • 3.5 Validating wear models
      • 3.6 Future trends
      • 3.7 References
      • 3.8 Appendix: useful tables
  • Part II: Computational modelling of musculoskeletal cells and tissues
    • 4. Computational modeling of cell mechanics
      • Abstract:
      • 4.1 Introduction
      • 4.2 Mechanobiology of cells
      • 4.3 Computational descriptions of whole-cell mechanics
      • 4.4 Liquid drop models
      • 4.5 Solid elastic models
      • 4.6 Power-law rheology model
      • 4.7 Biphasic model
      • 4.8 Tensegrity model
      • 4.9 Semi-flexible chain model
      • 4.10 Dipole polymerization model
      • 4.11 Brownian ratchet models
      • 4.12 Dynamic stochastic mode

Details

No. of pages:
550
Language:
English
Copyright:
© 2014
Published:
Imprint:
Woodhead Publishing
Print ISBN:
9780857096616
Electronic ISBN:
9780857096739