Computational Biomechanics - 1st Edition - ISBN: 9780128113684

Computational Biomechanics

1st Edition

Editors: Amir,A Zadpoor Hongyan Yuan
Paperback ISBN: 9780128113684
Imprint: Academic Press
Published Date: 1st September 2018
Page Count: 450
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Computational Biomechanics of Musculoskeletal Tissues is an accessible comprehensive text for teaching and for further reading. It focuses on use of patient-specific finite element models in tissue biomechanics. This book is a collection of papers from subject experts, from a biomedical engineering perspective. Each chapter consistently takes a systematic approach to problem solving within computational biomechanics using open source software tools. Verification and validation process for models is also covered. Methods are presented as case studies so readers can easily replicate results.

Content covered includes:

  • Multi-physics, multi-scale, and multi-domain approaches
  • Molecular dynamics, continuum and FEA models
  • Cell mechanics
  • Material models

Key Features

  • Covers fundamentals and applications of computational biomechanics in tissue engineering
  • Includes unique focus on tissue biomechanics
  • Use of open source software tools FEBio and OpenSim for computational biomechanical modeling are covered


Graduate students and researchers in biomechanics, biomaterials, tissue engineering and biomedical engineering

Table of Contents

Part I- General topics

1. Computational biomechanics: multi-physics, multi-scale, and multi-domain approaches

Amir Zadpoor, Delft University of Technology, The Netherlands

2. Multi-scale computational biomechanics


3. Mixture theory

Gerard Ateshian, Columbia University, US

4. Molecular dynamics models of skeletal tissues

Markus Buehler, MIT, US

5. Inverse problems in computational biomechanics

Stephane Avril, Mines-Saint-Etienne, France

Part II- Tissue biomechanics

6. Continuum models of bone biomechanics

Steve Cowin, CUNY (The City University of New York), US

7. Finite element models of bone at the micro-scale

Bert van Rietbergen, Eindhoven University of Technology, The Netherlands

8. Computational cartilage biomechanics

Van C Mow and/or Gerard Ateshian, Columbia University, US

9. Computational models of diffusion in cartilage

Harrie Weinans, Utrecht University Medical Center, The Netherlands

10. Finite element models of skeletal muscle

Silvia Salinas Blemker, University of Virginia, US

11. Computational biomechanics of soft skeletal tissues (tendon, ligament, etc)

Gerhard Holzapfel, Graz University of Technology, Austria


Jeffrey A. Weiss, University of Utah, US

12. Biomechanics of intervertebral disc

Aboulfazl Shirazi-Adl, École Polytechnique, Montréal, Canada

13. Biomechanics of the implant-tissue complex

Mark Taylor, Flinders University, Australia

14. Computational biomechanics of blast injuries

Anthony Bull, Imperial College London, UK

Part III- From cells to tissues

15. Computational cell mechanics

Mohammad Mofrad, University of California, Berkeley, US

16. Theoretical models of tissue growth, remodeling, and adaptation

J.D. Humphrey, Yale University, US

17. Computational tissue engineering

Scott Hollister, University of Michigan, US

Part IV- Multi-domain computational biomechanics

18. Statistical shape and appearance models of tissues

Tim Cootes, University of Manchester, UK

19. Large-scale musculoskeletal models

Markus Pandy, University of Melbourne, Australia

20. Patient-specific computational biomechanics models


Part V- Open source software for computational biomechanics

21. FEBio: An open source program for finite element modeling in biomechanics

Jeffrey Weiss, University of Utah, US

22. OpenSim: An open source program for musculoskeletal modeling

Scott Delp, Stanford University, US


No. of pages:
© Academic Press 2019
Academic Press
Paperback ISBN:

About the Editor

Amir,A Zadpoor

Dr. Amir A. Zadpoor received the Early Career Researcher Award on the 6th International Conference on Mechanics of Biomaterials and Tissues in Dec 2015. His research interests include additive manufacturing, biofabrication, biomaterials, and tissue biomechanics. He is an editor on Elsevier’s journal Mechanical Behavior of Biomedical Materials. He has written over 100 articles, and serves on 13 academic editorial boards.

Affiliations and Expertise

Associate Professor and Chair of Biomaterials & Tissue Biomechanics, Department of Biomechanical Engineering, Faculty of Mechanical, Maritime, and Materials Engineering, Delft University of Technology (TUDelft), The Netherlands

Hongyan Yuan

Dr Hongyan Yuan, PhD is currently Assistant Professor of Mechanical Engineering at University of Rhode Island

Affiliations and Expertise

Assistant Professor, Department of Mechanical, Industrial and Systems Engineering, University of Rhode Island, Kingston, RI, USA

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