
Comprehensive Medicinal Chemistry III
Description
Key Features
- Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry
- Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets
- Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
Readership
Graduate and postgraduate drug discovery scientists in research organizations engaged in the discipline, primarily but not exclusively medicinal chemists. Computational chemists, therapeutic area biologists and pharmacologists, ADME scientists as well as process chemists. A medicinal chemist at any point in his/her career who desires an up-to-date source of information on not only the latest trends in the discipline, but also specifics on the newest information in a particular field such as biologics and specific discovery targets such as kinase inhibitors in cancer
Table of Contents
Volume 1: General Perspective - The Future of Drug Discovery
Volume 2: Drug Discovery Technologies
Volume 3: In Silico Drug Discovery Tools
Volume 4: Experimental ADME and Toxicology
Volume 5: Cancer, Immunology and Inflammation, and Infectious Disease
Volume 6: CNS, Pain, Metabolic Syndrome, Urology, Gastrointestinal and Cardiovascular
Volume 7: Biologics Medicine
Volume 8: Case Histories in Recent Drug Discovery
Product details
- No. of pages: 4536
- Language: English
- Copyright: © Elsevier 2017
- Published: June 3, 2017
- Imprint: Elsevier
- Hardcover ISBN: 9780128032008
- eBook ISBN: 9780128032015
About the Editors in Chief
Samuel Chackalamannil
Dr. Chackalamannil led the discovery of vorapaxar (Zontivity®), an FDA approved antiplatelet drug for the prevention of heart attack and stroke. His group also discovered a PDE-5 inhibitor clinical candidate dasantafil and an adenosine A2a antagonist clinical candidate for the treatment of Parkinson’s disease. Dr. Chackalamannil is a two-time recipient of the Thomas Alva Edison Award for Emerging Technology Patent and a two-time recipient of the Presidential Award for Discovery at Schering-Plough Research Institute.
Dr. Chackalamannil is a co-inventor of 61 allowed US patents and numerous patent applications worldwide. He has published 82 peer-reviewed journal articles and book chapters, has co-authored a book and has given numerous lectures at international meetings and academic institutions. Dr. Chackalamannil has served as a section editor for Current Opinion in Drug Discovery and he has chaired several sessions at American Chemical Society National Meetings and Gordon Research Conference on Medicinal Chemistry.
Affiliations and Expertise
David Rotella
Affiliations and Expertise
Simon Ward
Affiliations and Expertise
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