Comprehensive Medicinal Chemistry II

1st Edition

Volume 6: THERAPEUTIC AREAS I: Central Nervous System, Pain, Metabolic Syndrome, Urology, Gastrointestinal and Cardiovascular


  • Michael Williams
    • Print ISBN 9780080445199


    This volume reviews important therapeutic areas, their causes, diagnosis, experimental disease models, treatments, unmet medical needs and future research areas. Areas covered include CNS diseases (schizophrenia, anxiety, Alzheimer's), Pain, Metabolic syndrome (obesity, diabetes), Urogenital, Gastrointestinal (IBS) and Cardiovascular. Experts examine the key roles that medicinal chemistry and pharmacology play in reviving the fortunes of the drug discovery process and developing new treatment for each therapeutic areas.

    Key Features

    * valuable content available May 2009 as an individual volume
    * separate volumes will appeal to a wider chemistry, biochemistry and medicinal audience
    * priced for individual researcher as well as library purchase


    For students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.

    Table of Contents

    Volume 6 Therapeutic Areas I: Central Nervous System, Pain, Metabolic Syndrome, Urology, Gastrointestinal and Cardiovascular
    Central Nervous System
    6.01 Central Nervous System Drugs Overview
    6.02 Schizophrenia
    6.03 Affective Disorders: Depression and Bipolar Disorders
    6.04 Anxiety
    6.05 Attention Deficit Hyperactivity Disorder
    6.06 Sleep
    6.07 Addiction
    6.08 Neurodegeneration
    6.09 Neuromuscular/Autoimmune Disorders
    6.10 Stroke/Traumatic Brain and Spinal Cord Injuries
    6.11 Epilepsy
    6.12 Ophthalmic Agents
    6.13 Pain Overview
    6.14 Acute and Neuropathic Pain
    6.15 Local and Adjunct Anesthesia
    6.16 Migraine
    Obesity/Metabolic Disorders/Syndrome X
    6.17 Obesity/Metabolic Syndrome Overview
    6.18 Obesity/Disorders of Energy
    6.19 Diabetes/Syndrome X
    6.20 Atherosclerosis/Lipoprotein/Cholesterol Metabolism
    6.21 Bone, Mineral, Connective Tissue Metabolism
    6.22 Hormone Replacement
    6.23 Urogenital Diseases/Disorders, Sexual Dysfunction and Reproductive
    Medicine: Overview
    6.24 Incontinence (Benign Prostatic Hyperplasia/Prostate Dysfunction)
    6.25 Renal Dysfunction in Hypertension and Obesity
    6.26 Gastrointestinal Overview
    6.27 Gastric and Mucosal Ulceration
    6.28 Inflammatory Bowel Disease
    6.29 Irritable Bowel Syndrome
    6.30 Emesis/Prokinetic Agents
    6.31 Cardiovascular Overview
    6.32 Hypertension
    6.33 Antiarrhythmics
    6.34 Thrombolytics


    No. of pages:
    © 2007
    Elsevier Science
    Print ISBN: