Comprehensive Medicinal Chemistry II - 2nd Edition - ISBN: 9780080450445

Comprehensive Medicinal Chemistry II

2nd Edition

eBook ISBN: 9780080450445
Imprint: Elsevier Science


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The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well.Comprehensive Medicinal Chemistry II will be available online in 2007 via the proven platform ScienceDirect providing the user with enhanced features such as cross-referencing and dynamic linking.

Table of Contents

Volume 1 Global Perspective (P. Kennewell).

Volume 2 Research and Development (W.H. Moos).

Volume 3 Technologies (H. Kubinyi).

Volume 4 Computer-Assisted Drug Design (J.S. Mason).

Volume 5 ADME-Tox Approaches (B. Testa and H. van de Waterbeemd).

Volume 6 Therapeutic Areas I (M. Williams).

Volume 7 Therapeutic Areas II (J. Plattner and M.C. Desai).

Volume 8 Case Histories and Cumulative Subject Index (J.B. Taylor and D.J. Triggle).


Elsevier Science
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Reviews from the first edition:
"Beautifully produced six-part magnum opus of medicinal chemistry. Comprehensive and remarkably up-to-date. The preface boasts a milestone in the literature of the subject in terms of coverage, clarity and presentation’ with which I agree." --The LANCET

"A most impressive collection of up to date, excellently referenced reviews covering virtually every aspect of biological science of relevance to the production of medicines." --Chemistry in Britain