Key Features

  • Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume.
  • See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations.
  • Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis.
  • Get specific insight into prevention and treatment of hypertension in special populations.
  • Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Table of Contents

SECTION 1 - EPIDEMIOLOGY

*Blood pressure in Westernized populations
*Low blood pressure populations, the impact of rural -urban migration
*Regional differences in blood pressure in developed countries
*Low blood pressure populations, the impact of rural -urban migration
*Fetal influences on blood pressure: the Barker hypothesis
*Blood pressure and the risks of cardiovascular disease and stroke

SECTION 2 - PATHOGENESIS OF HYPERTENSION - HEMODYNAMICS AND VASCULAR MECHANISMS

*Haemodynamics of essential hypertension
*Genetic models of hypertension
*Experimental models of hypertension
*Left ventricular physiology in hypertension
*The arterial system in human hypertension
*Resistance vessels in hypertension
*Endothelial function
*Vascular growth, angiogenesis and hypertension
*Vascular smooth muscle
*Cell membranes - vascular smooth muscle action transport - vascular smooth muscle regulation by calcium magnesium and potassium
*Coagulation and platelet abnormalities
*Cytokines and inflammation

SECTION 3 - PATHOGENESIS OF HYPERTENSION - RENAL AND NEUROHUMORAL MECHANISMS

*Role of the kidney
*Autonomic control and hemodynamics of hypertension, baroreceptor function and reflexes
*Central nervous control of blood pressure
*The Renin-Angiotensin System
*Aldosterone and other adrenal steroids
*The endothelins
*Nitric oxide
*Reactive oxygen species and oxidative stress
*The natriuretic peptides
*Other peptide and related systems
*Other peptide and related systems
*Eicosanoids
*The kallikrein-kinin systems
*Sex steroids - estrogens and testosterone

SECTION 4 - PATHOGENESIS OF HYPERTENSION - GENETICS AND LIFESTYLE

*Genetic approaches to hypertension: relevance to human hypertension
*Monogenic forms of human hypertension
*Potential role of gene th

Details

No. of pages:
1248
Language:
English
Copyright:
© 2007
Published:
Imprint:
Mosby
Print ISBN:
9780323039611
Electronic ISBN:
9780323070676