Comprehensive Hypertension

1st Edition

Authors: Gregory Lip John Hall
Hardcover ISBN: 9780323039611
eBook ISBN: 9780323070676
Imprint: Mosby
Published Date: 19th June 2007
Page Count: 1248

Description

Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book.

Key Features

  • Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume.
  • See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations.
  • Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis.
  • Get specific insight into prevention and treatment of hypertension in special populations.
  • Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.

Table of Contents

SECTION 1 - EPIDEMIOLOGY

Blood pressure in Westernized populations
Low blood pressure populations, the impact of rural -urban migration
Regional differences in blood pressure in developed countries
Low blood pressure populations, the impact of rural -urban migration
Fetal influences on blood pressure: the Barker hypothesis
Blood pressure and the risks of cardiovascular disease and stroke

SECTION 2 - PATHOGENESIS OF HYPERTENSION - HEMODYNAMICS AND VASCULAR MECHANISMS

Haemodynamics of essential hypertension
Genetic models of hypertension
Experimental models of hypertension
Left ventricular physiology in hypertension
The arterial system in human hypertension
Resistance vessels in hypertension
Endothelial function
Vascular growth, angiogenesis and hypertension
Vascular smooth muscle
Cell membranes - vascular smooth muscle action transport - vascular smooth muscle regulation by calcium magnesium and potassium
Coagulation and platelet abnormalities
Cytokines and inflammation

SECTION 3 - PATHOGENESIS OF HYPERTENSION - RENAL AND NEUROHUMORAL MECHANISMS

Role of the kidney
Autonomic control and hemodynamics of hypertension, baroreceptor function and reflexes
Central nervous control of blood pressure
The Renin-Angiotensin System
Aldosterone and other adrenal steroids
The endothelins
Nitric oxide
Reactive oxygen species and oxidative stress
The natriuretic peptides
Other peptide and related systems
Other peptide and related systems
Eicosanoids
The kallikrein-kinin systems
Sex steroids - estrogens and testosterone

SECTION 4 - PATHOGENESIS OF HYPERTENSION - GENETICS AND LIFESTYLE

Genetic approaches to hypertension: relevance to human hypertension
Monogenic forms of human hypertension
*Potential role of gene th

Details

No. of pages:
1248
Language:
English
Copyright:
© Mosby 2007
Published:
Imprint:
Mosby
eBook ISBN:
9780323070676
Hardcover ISBN:
9780323039611

About the Author

Gregory Lip

Affiliations and Expertise

Consultant Cardiologist, University Department of Medicine, City Hospital Birmingham, UK

John Hall

Affiliations and Expertise

Arthur C. Guyton Professor and Chair, Department of Physiology and Biophysics, Director, Mississippi Center for Obesity Research, University of Mississippi Medical Center, Jackson, Mississippi