Comprehensive Heterocyclic Chemistry III, 15-Volume Set

1st Edition

A Review of the Literature 1995-2007 1- 15

Hardcover ISBN: 9780080449913
eBook ISBN: 9780080449920
Imprint: Elsevier Science
Published Date: 5th March 2008
Page Count: 12500

Institutional Access


Comprehensive Heterocyclic Chemistry III (CHEC-III) is a new 15-volume reference work which provides the first point of entry to the literature for all scientists interested in heterocyclic ring systems. Since publishing in 1984, Comprehensive Heterocyclic Chemistry (CHEC) has become the standard work on the subject, indispensable to all serious readers in the interdisciplinary areas where heterocycles are employed. CHEC-III builds on and complements the material in CHEC and CHEC-II and is designed to be used both alone and in conjunction with these two works. Written by leading scientists who have evaluated and summarized the most important data published over the last decade, Comprehensive Heterocyclic Chemistry III will be an invaluable addition to the reference library of those working with heterocyclic ring systems.

Key Features

  • Reviews advances in the properties, structure, synthesis, reactivity and applications of the most important heterocyclic ring systems
  • Contains over 250 specialist reviews, logically organized by size and heteroatom content of the heterocyclic ring
  • Saves researchers valuable time and effort through carefully structured critical reviews of the literature by experts


For academic, industrial and government scientists working in chemical, biological, pharaceutical, medicinal and natural product research, together with teachers and advanced students interested in the formation (synthesis) and transformation of heterocyclic ring systems.

Table of Contents

CHEC III is organized in 15 Volumes and closely follows the organization used in the previous edition:

Volumes 1 and 2: Cover respectively three- and four-membered heterocycles, together with all fused systems containing a three- or four-membered heterocyclic ring.

Volume 3: Five-membered rings with one heteroatom together with their benzo- and other carbocyclic-fused derivatives.

Volumes 4, 5 and 6: Cover five-membered rings with two heteroatoms, and three or more heteroatoms, respectively, each with their fused carbocyclic compounds.

Volumes 7, 8 and 9: Dedicated to six-membered rings with one, two, and more than two heteroatoms, respectively, again with the corresponding fused carbocylic compounds.

Volumes 10, 11 and 12: Cover systems containing at least two directly fused heterocyclic five- and/or six-membered rings: of these Volume 10 deals with bi-heterocyclic rings without a ring junction heteroatom, and Volume 11 deals with 5:5 and 5:6 fused rings systems with at least one ring junction nitrogen, while Volume 12 is devoted to all other systems of five and/or six-membered fused or spiro heterocyclic rings with ring junction heteroatoms.

Volumes 13 and 14: Seven-membered and larger heterocyclic rings including all their fused derivatives (except those containing three- or four-membered heterocyclic rings which are included in Volume 1 and 2, respectively).

Volume 15: Author, ring and subject indexes.


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Elsevier Science
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"This reviewer examined selected print volumes from the set and found them to be excellent in general …Recommended. Upper-division undergraduate through professional library collections." --R.E. Buntrock, CHOICE, October 2008

"A must for all chemistry libraries and those research groups employing heterocyclic chemistry. Also libraries used by scientists working on biological problems, on natural products or in material sciences should have access to Comprehensive Heterocyclic Chemistry II" --Synthesis, 1998

"Overall this set of books is successful and impressive. It will be extremely useful to anyone pursuing research in heterocyclic chemistry, and it belongs in every chemistry library. It will be consulted frequently and extensively" --J. Med. Chem, 1997

"Its logical organization and text-based approach make it easier for nonspecialists and advanced students to consult, and its indexes are very thorough and very helpful" --D. Flaxbart, J. Am. Chem. Soc., 1997

"Provides chemists, and biologists working at the chemical interface, with an impressive body of collected knowledge which is not available from any other source" --Nature, 1985

"The general chapters enable interested students to find their bearings . . . The specialised chapters are available to meet the demand for more detailed information - even experts in universities and industry will find useful references here." --E. Schaumann, Angew. Chem., 1985

"No institution should be without their reference copy and many will want to make the materials as accessible as possible to students, faculty and research investigators" --D.L. Boger, J. Pharm. Sci., 1985