Comparative Transfusion Medicine - 1st Edition - ISBN: 9780120392360, 9780323154437

Comparative Transfusion Medicine

1st Edition

Editors: Susan Cotter
eBook ISBN: 9780323154437
Imprint: Academic Press
Published Date: 28th October 1991
Page Count: 358
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Description

Comparative Transfusion Medicine describes the role of animals as donors in early human transfusions. Organized into 11 chapters, the book focuses on specific animal models of human hematologic diseases. After briefly dealing with the history of transfusion in medicine, the book discusses erythrocytes, white cells, platelets, and coagulation in various animal species, and then describes specific animal models of human hematologic diseases. It then considers the progress in bone marrow transplantation by pioneering histocompatibility studies of dogs. The discussion then shifts to the preparation components and clinical veterinary transfusions. The book also presents three problems in neonatal transfusion, including the failure of passive transfer, isoerythrolysis, and immunotherapy. The concluding chapters explore the developments in human autologous transfusion, blood substitutes, and hematopoietic growth factors. The book is of great value to veterinarians involved in research or in clinical transfusions, and to physicians and other scientists using animals in research.

Table of Contents

Contributors Preface History of Transfusion Medicine I. Early Concepts and Practices II. Twentieth Century Advances References Erythrocytes I. Erythrocyte Physiology II. Erythrocyte Life Span III. Effects of Oxidative Stress IV. Animal Models of Inherited Erythrocyte Disorders V. Immunological Aspects of Animal Erythrocytes References White Cells I. Granulocyte Production and Kinetics II. Granulocyte Function III. Granulocyte-Mediated Tissue Injury IV. Disorders of Granulocyte Numbers V. Disorders of Neutrophil Function VI. Therapeutic Granulocyte Transfusion VII. Diagnostic Granulocyte Transfusion VIII. Conclusions References Platelets and Coagulation I. Introduction II. Physiology of Hemostasis III. Laboratory Evaluation of Hemostasis IV. Disorders of Hemostasis V. Summary References Histocompatibility and Bone Marrow Transplantation I. Histocompatibility II. Allogeneic Bone Marrow Transplantation III. Autologous Bone Marrow Transplantation IV. Conclusions References Preparation of Components I. Blood Donor Selection II. Canine and Feline Donor Maintenance III. Hospitalized Donors versus Outpatient Donor Program IV. Collection of Blood and Preparation of Components V. Storage of Blood Products VI. Hemapheresis References Clinical Transfusion Medicine I. Pretransfusion Considerations II. Transfusion in Hemorrhagic Shock III. Transfusion in Surgery IV. Treatment of Hemolytic Anemia V. Transfusion in Chronic Blood Loss VI. Transfusion in Anemia from Lack of Red Cell Production VII. Transfusion of Plasma VIII. Transfusion of Platelets IX. Transfusion of Granulocytes X. Adverse Effects of Transfusions XI. Therapeutic Apheresis References Neonatal Transfusion Medicine I. Introduction II. Failure of Passive Transfer III. Neonatal Isoerythrolysis IV. Specific Immunotherapy References Autologous Transfusion

Details

No. of pages:
358
Language:
English
Copyright:
© Academic Press 1991
Published:
Imprint:
Academic Press
eBook ISBN:
9780323154437

About the Editor

Susan Cotter

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