Comparative Biochemistry of Parasites

Comparative Biochemistry of Parasites

1st Edition - January 28, 1972

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  • Editor: H Van den Bossche
  • eBook ISBN: 9780323146883

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Comparative Biochemistry of Parasites contains the proceedings of an international symposium organized by the Janssen Research Foundation and held at Janssen Pharmaceutica in Belgium on September 1-3, 1971. The symposium reviewed progress in the understanding of the physiology and biochemistry of parasites such as protozoa and helminths. Organized into 34 chapters, this volume begins with an overview of early research on parasite biochemistry before turning to a discussion of antischistosomal drugs and their biochemical effects on parasites. The reader is then introduced to the biochemistry of carbohydrates in nematodes and cestodes; neurotransmitters in trematodes; pharmacological aspects and biochemical effects of tetramisole; the mechanism of action of berenil (Diminazene) and related compounds; and dihydrofolate reductases in parasitic protozoa and helminths. Other chapters focus on the loss of fatty acid biosynthesis in flatworms, the cytochrome system in Kinetoplastidae, oxidative phosphorylation in Moniezia mitochondria, and the role of non-heme iron in cestode respiration. Scientists, particularly physiologists and biochemists, will find this book an invaluable source of information on parasite physiology and biochemistry.

Table of Contents

  • Participants


    1. Glimpses at the Early Days of Parasite Biochemistry

    2. Biochemical Effects of Antischistosomal Drugs

    3. Comparative Biochemistry of Carbohydrates in Nematodes and Cestodes

    4. The Utilization of Carbon Dioxide by Moniezia expansa: Aspects of Metabolic Regulation

    5. Hormones, the Environment, and Development in Nematodes

    6. Neurotransmitters in Trematodes

    7. Pharmacological Aspects of Tetramisole

    8. Biochemical Effects of Tetramisole

    9. Recent Studies on the Mechanism of Action of Berenil (Diminazene) and Related Compounds

    10. Biochemical Effects of the Anthelmintic Drug Mebendazole

    11. Kinetoplast DNA: Structure and Function

    12. Organization of the DNA in the Kinetoplast of Trypanosomatidae

    13. DNA of Kinetoplastidae: A Comparative Study

    14. Some Studies on the DNA of Plasmodium knowlesi

    15. Dihydrofolate Reductases in Parasitic Protozoa and Helminths

    16. Physiological Adaptability of Malaria Parasites

    17. Cytochemical and Biochemical Studies of the Intestinal Cells of Ascaris suum

    18. Factors Influencing the Movement of Materials across the Intestine of Ascaris

    19. Acid Phosphatases in the Intestinal Cells of Two Nematode Larvae: Anisakis sp. and Trichinella spiralis

    20. Studies on Acid Hydrolases and on Catalase of the Trypanosomatid Crithidia luciliae

    21. Structural and Biochemical Changes in Nippostrongylus brasiliensis during Development of Immunity to this Nematode in Rats

    22. Adaptations in Oxidative Metabolism during the Transformation of Trypanosoma rhodesiense from Bloodstream into Culture Form

    23. Effects of Bongkrekic Acid on Malaria Parasites (Plasmodium lophurae) Developing Extracellularly in Vitro

    24. Carbohydrate Metabolism in Entamoeba histolytica

    25. Biochemistry of Coccidia

    26. Loss of Fatty Acid Biosynthesis in Flatworms

    27. Recent Studies on the Characterization of the Cytochrome System in Kinetoplastidae

    28. Cytochromes in Ascaris and Moniezia

    29. Role of Non-heme Iron in Cestode Respiration

    30. Effects of Anthelmintics on P32 Esterification in Helminth Metabolism 445

    31. Studies on the Phosphorylation in Ascaris Mitochondria

    32. The Influence of the Lipophilic and Electronic Character of Substituted Phenols on the Effectors of Ascaris suum Mitochondria

    33. Oxidative Phosphorylation in Moniezia Mitochondria

    34. Summary and Outlook

    Subject Index

Product details

  • No. of pages: 532
  • Language: English
  • Copyright: © Academic Press 1972
  • Published: January 28, 1972
  • Imprint: Academic Press
  • eBook ISBN: 9780323146883

About the Editor

H Van den Bossche

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