Volume 126. Cognition, Emotion and Autonomic Responses: The Integrative Role of the Prefrontal Cortex and Limbic Structures

1st Edition



Since the publication of the previous volume on the prefrontal cortex: its structures, function and pathology in Progress in Brain Research some ten years ago, new data has emerged on the prefrontal cortex and its connections and interactions with structures involved in emotional, motivational and autonomic responses. Cognition, memory and decision making appear to be influenced by emotional and autonomic responses from viscera and the internal state of the organism (e.g. 'gut feelings') induced by the outside world. This resulted in a renewed interest in the interactions of circuits involved in cognition, memory and decision making with those involved in emotional and motivational responses. Therefore, the 21st International Summer School of Brain Research, held in Amsterdam, 23-27 August 1999, was entirely devoted to the question to which extent the prefrontal cortex and related limbic structures function as an integrative center for these interactions.

Table of Contents

List of contributors. List of Participants. Preface. Acknowledgements. Section I. Circuitry for cognition and emotion. 1. The prefrontal cortex and the integration of sensory, limbic and autonomic information (H.J. Groenewegen, H.B.M. Uylings). 2. Neurobiological mechanisms of emotionally influenced, long-term memory (L. Cahill). 3. Hypothalamic connections with the cerebral cortex (C.B. Saper). 4. Functional neuroanatomy of the prefrontal cortex: autonomic interactions (C.G. Van Eden, R.M. Buijs). Section II. Attention and decision making. 5. Functional anatomy of arousal and attention systems in the human brain (T. Paus). 6. Attentional processes and learning and memory in rats: the prefrontal cortex and hippocampus compared (L.M. Broersen). 7. Limitations in information processing in the human brain: neuroimaging of dual task performance and working memory tasks (T. Klingberg). 8. Role of the prefrontal cortex of the rat in learning and decision making: effects of transient inactivation (J.P.C. De Bruin, M.G.P. Feenstra, L.M. Broersen, M. Van Leeuwen, C. Arens, S. De Vries, R.N.J.M.A. Joosten). Section III. Stress and reward systems in cognition. 9. The integration of stress by the hypothalamus, amygdala and prefrontal cortex: balance between the autonomic nervous system and the neuroendocrine system (R.M. Buijs, C.G. van Eden). 10. Dopamine and noradrenaline release in the prefrontal cortex in relation to unconditioned and conditioned stress and reward (M.G.P. Feenstra). 11. Locus coeruleus and regulation of behavioral flexibility and attention (G. Aston-Jones, J. Rajkowski, J. Cohen). 12. Stress impairs prefrontal cortical function in rats and monkeys: role of dopamine D1 and norepinephrine &agr;-1 receptor mechanisms (A.F.T. Arnsten). 13. Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior (J.R. Hollerman, L. Tremblay, W. Schultz). 14. Reward-dependent learning in neuronal netw


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© 2000
Elsevier Science
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