CNS Pharmacology Neuropeptides - 1st Edition - ISBN: 9780080280219, 9781483148441

CNS Pharmacology Neuropeptides

1st Edition

Proceedings of the 8th International Congress of Pharmacology, Tokyo, 1981

Editors: H. Yoshida Y. Hagihara S. Ebashi
eBook ISBN: 9781483148441
Imprint: Pergamon
Published Date: 1st January 1982
Page Count: 296
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Description

Advances in Pharmacology and Therapeutics II, Volume 1: CNS Pharmacology Neuropeptides contains the proceedings of the Eighth International Congress of Pharmacology held in Tokyo in 1981. This book is the first of a six-volume compilation of the scientific papers of invited speakers. Separating 26 papers as chapters, this book begins with an invited lecture on opioid peptides and their receptors. Other chapters describe opioid peptides and their relevance to central nervous system mechanisms; neuropeptides and related compounds affecting learning and memory; and pharmacological approaches to the study of sleep regulation. This book also explores the importance of kainic acid and related compounds as a pharmacological tool.

Table of Contents


Introduction

Invited Lecture

Opioid peptides and their receptors

Opioid Peptides and their Relevance for CNS Mechanisms

Role of "enkephalinase" (enkephalin-dipeptidylcar-boxypeptidase) as synaptic neuropeptidase

Opioid peptides and analgesia: sites of action

Intrathecal use of beta-endorphin as a powerful analgetic agent in man

Endorphins and thyrotropin releasing hormone in shock and trauma

Endorphins - clinical relevance in neurology

On the role of endorphins in addiction

Invited Lecture

Critical review of pain relieving procedures including acupuncture

Substance P

Substance P-mediated synaptic excitation in mammalian spinal cord and sympathetic ganglia

Substance P in the intestine

Substance P and the primary afferent neuron

Invited Lecture

Inhibitors of prolactin secretion

Invited Lecture

Anorectic agents and satietin, an endogenous inhibitor of food intake

Neuropeptides and Related Compounds Affecting Learning and Memory

Neuropeptides and emotional behavior

Neurohypophyseal hormones and memory

Neuropeptides and morphine tolerance

Neurohypophyseal hormones and addiction

Pharmacological Approaches to the Study of Sleep Regulation

Sleep as a dynamic process

Purification of sleep-promoting substances (SPS)

The search for circulating sleep-promoting factors

Voltammetric detection of brain 5-hydroxyindolacetic acid fluctuations during the sleep-waking cycle

Neuropharmacological tests of the reciprocal interaction model of sleep cycle control

Kainic Acid and Related Compounds as a Pharmacological Tool

Actions of kainic acid and related analogues on Hirudo, Helix and LimuJus central neurones

A comparison between the glutamate response and the excitatory junctional potential in the presence of kainic acid at the crayfish neuromuscular junction

Kainic acid: neurotoxicity and receptor interactions

A posible mechanism for excitant amino acid toxicity

Index




Details

No. of pages:
296
Language:
English
Copyright:
© Pergamon 1982
Published:
Imprint:
Pergamon
eBook ISBN:
9781483148441

About the Editor

H. Yoshida

Affiliations and Expertise

Osaka International University for Women, Osaka, Japan

Y. Hagihara

S. Ebashi

Affiliations and Expertise

National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan

Ratings and Reviews