CNS Pharmacology Neuropeptides

CNS Pharmacology Neuropeptides

Proceedings of the 8th International Congress of Pharmacology, Tokyo, 1981

1st Edition - January 1, 1982

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  • Editors: H. Yoshida, Y. Hagihara, S. Ebashi
  • eBook ISBN: 9781483148441

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Advances in Pharmacology and Therapeutics II, Volume 1: CNS Pharmacology Neuropeptides contains the proceedings of the Eighth International Congress of Pharmacology held in Tokyo in 1981. This book is the first of a six-volume compilation of the scientific papers of invited speakers. Separating 26 papers as chapters, this book begins with an invited lecture on opioid peptides and their receptors. Other chapters describe opioid peptides and their relevance to central nervous system mechanisms; neuropeptides and related compounds affecting learning and memory; and pharmacological approaches to the study of sleep regulation. This book also explores the importance of kainic acid and related compounds as a pharmacological tool.

Table of Contents

  • Introduction

    Invited Lecture

    Opioid peptides and their receptors

    Opioid Peptides and their Relevance for CNS Mechanisms

    Role of "enkephalinase" (enkephalin-dipeptidylcar-boxypeptidase) as synaptic neuropeptidase

    Opioid peptides and analgesia: sites of action

    Intrathecal use of beta-endorphin as a powerful analgetic agent in man

    Endorphins and thyrotropin releasing hormone in shock and trauma

    Endorphins - clinical relevance in neurology

    On the role of endorphins in addiction

    Invited Lecture

    Critical review of pain relieving procedures including acupuncture

    Substance P

    Substance P-mediated synaptic excitation in mammalian spinal cord and sympathetic ganglia

    Substance P in the intestine

    Substance P and the primary afferent neuron

    Invited Lecture

    Inhibitors of prolactin secretion

    Invited Lecture

    Anorectic agents and satietin, an endogenous inhibitor of food intake

    Neuropeptides and Related Compounds Affecting Learning and Memory

    Neuropeptides and emotional behavior

    Neurohypophyseal hormones and memory

    Neuropeptides and morphine tolerance

    Neurohypophyseal hormones and addiction

    Pharmacological Approaches to the Study of Sleep Regulation

    Sleep as a dynamic process

    Purification of sleep-promoting substances (SPS)

    The search for circulating sleep-promoting factors

    Voltammetric detection of brain 5-hydroxyindolacetic acid fluctuations during the sleep-waking cycle

    Neuropharmacological tests of the reciprocal interaction model of sleep cycle control

    Kainic Acid and Related Compounds as a Pharmacological Tool

    Actions of kainic acid and related analogues on Hirudo, Helix and LimuJus central neurones

    A comparison between the glutamate response and the excitatory junctional potential in the presence of kainic acid at the crayfish neuromuscular junction

    Kainic acid: neurotoxicity and receptor interactions

    A posible mechanism for excitant amino acid toxicity


Product details

  • No. of pages: 296
  • Language: English
  • Copyright: © Pergamon 1982
  • Published: January 1, 1982
  • Imprint: Pergamon
  • eBook ISBN: 9781483148441

About the Editors

H. Yoshida

Affiliations and Expertise

Osaka International University for Women, Osaka, Japan

Y. Hagihara

S. Ebashi

Affiliations and Expertise

National Institute for Physiological Sciences, Myodaiji, Okazaki, Japan

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