Description

The biological function of clusterin (CLU, also known as ApoJ, SGP2, TRPM2, CLI) has been puzzling researchers since its discovery and characterization in the early 1980s. Approaches such as cloning, expression and functional characterization of the different protein products generated by the CLU gene have now produced a critical mass of information of tremendous biological importance that are teaching us an important lesson in molecular biology of gene expression regulation. This volume brings together the contributions of top researchers in the field, providing an overview and synthesis of the latest thought and findings relating to CLU.

Readership

Researchers and students in the basic and clinical sciences of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology, and molecular biology.

Details

No. of pages:
350
Language:
English
Copyright:
© 2009
Published:
Imprint:
Academic Press
Print ISBN:
9780123747723
Electronic ISBN:
9780080912257

Reviews

"This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences."
-- American Scientist
"Excellent, highly informative, in-depth reviews...expertly written, up-to-date, and well-referenced."
-- Journal of Medicinal Chemistry
"This is a series that has a long tradition of excellence in the field of cancer biology."
-- Doody's Publishing Reviews