Key Features

  • Evidence-based research to guide clinical practice.
  • Coverage of treatment trials including Glycoprotein IIb/IIa receptor inhibitors, aspirin, drug therapies for arrhythmias, and pacing.
  • Expanded section on prevention of cardiac disease
  • Covers both prevention and treatment.

Table of Contents

Section I. METHODOLOGY

Chapter 1: Contributions of Basic Research, Observational Studies, and Randomized Trials
Chapter 2: Methodology of Randomized Trials
Chapter 3: Comparative Features of Primordial, Primary and Secondary Prevention Trials
Chapter 4: Principles of Data and Safety Monitoring Boards in Randomized Trials

Section II. TREATMENT TRIALS

A. Treatment of Acute Coronary Ischemia

Chapter 5: Aspirin and Thienopyridines
Chapter 6: Heparin and Low Molecular Weight Heparin in Acute Coronary Ischemia
Chapter 7: Clinical Trials in Thrombolytic Therapy
Chapter 8: Clinical Trials of Direct Thrombin Inhibitors
Chapter 9: Glycoprotein IIb/IIIa Receptor Inhibitors
Chapter 10: Adjunctive Medical Therapy for Acute Myocardial Infarction
Chapter 11: Primary, Rescue and Adjunctive Mechanical Intervention in the Setting of Acute Myocardial Infarction
Chapter 12: Coronary Artery Bypass Surgery in Acute Coronary Syndromes

B. Treatment of Arrhythmias

Chapter 13: Drug Therapy for Ventricular Tachycardia and Ventricular Fibrillation
Chapter 14: Antiarrhythmic Drug Therapy in Supraventricular Tachycardia
Chapter 15: Anticoagulant and Antiplatelet Drug Therapy for Atrial Fibrillation
Chapter 16: Clinical Trials in Arrhythmia Ablation
Chapter 17: Clinical Trials of Implantable Cardioverter-Defibrillators (ICDs) and Cardiac Resynchronization Therapy/Defibrillation
Chapter 18: Clinical Trials in Pacing

C. Treatment of Congestive Heart Failure

Chapter 19: Drugs Blocking the Renin-Angiotensin-Aldosterone System (RAAS)
Chapter 20: Beta-blocker Treatment of Heart Failure
Chapter 21: Clinical Trials in Heart Transplantation and Mechanical Cardiac Support for End-Stage Heart Failure

Section III. PRIMARY AND SECONDARY PREVENTION TRIALS

Chapter 22: Cholesterol Reduction
Chapter 23: Blood Pressure Reductio

Details

No. of pages:
448
Language:
English
Copyright:
© 2004
Published:
Imprint:
Saunders
Print ISBN:
9780721604084
Electronic ISBN:
9781437713084