Volume 25. Clinical Pharmacology and Therapeutics of Hypertension

1st Edition

Handbook of Hypertension Series


  • Gordan McInnes
    • Print ISBN 9780444517579

    Key Features

    • Volume in Handbook of Hypertension series.

    • International range of expert contributors.

    • Systematically reviews the clinical pharmacology of all the antihypertensive agents.

    • Also covers treatment of hypertension in special patient goups.

    • Includes covearge of latest clinical trials and prospects for the future.

    Table of Contents

    Section I: General considerations:

    Classification of antihypertensive drugs and pharmacological considerations. Interaction of antihypertensive drugs with mechanisms of blood pressure regulation. Antihypertensive drugs: pharmacokinetics, pharmacodynamics, metabolism, side effects and drug interactions. Antihypertensive drugs: hemodynamic effects.

    Section II: Diuretics:

    Thiazides and loop diuretics. Aldosterone antagonists

    Section III: Centrally acting drugs:

    Methyldopa and imidazolone agonists.

    Section IV: Vasodilator drugs:

    Alpha-blocking drugs. Calcium channel blockers. Potent vasodilators.

    Section V: Beta-blocking agents:

    Beta-adrenoceptor blocking drugs.

    Section VI: Drugs acting on the renin-angiotensin system:

    Angiotensin converting enzyme inhibitors. Angiotensin receptor blockers. Vasopeptidase inhibitors.

    Section VII: Future prospects:

    Novel agents in development.

    Section VIII: Clinical trials:

    The evidence-base for treatment of hypertension.

    Section IX: Therapeutic strategies:

    Combination therapy. Sequential monotherapy.

    Section X: Special patient groups:

    Pregnancy. The elderly. Hypertension and diabetes. Ethnic considerations in hypertension.


    No. of pages:
    © 2008
    Print ISBN: