Clinical Laboratory Science

Clinical Laboratory Science

Concepts, Procedures, and Clinical Applications

9th Edition - September 14, 2022

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  • Author: Mary Turgeon
  • Paperback ISBN: 9780323829342
  • eBook ISBN: 9780323832212

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Description

Using a discipline-by-discipline approach, Turgeon’s Clinical Laboratory Science: Concepts, Procedures, and Clinical Applications, 9th Edition, provides a fundamental overview of the concepts, procedures, and clinical applications essential for working in a clinical laboratory and performing routine clinical lab tests. Coverage includes basic laboratory techniques and key topics such as safety, phlebotomy, quality assessment, automation, and point-of-care testing, as well as discussion of clinical laboratory specialties. Clear, straightforward instructions simplify laboratory procedures and are guided by the latest practices and CLSI (Clinical and Laboratory Standards Institute) standards. Written by well-known CLS educator Mary Louise Turgeon, this edition offers essential guidance and recommendations for today’s laboratory testing methods and clinical applications.

Key Features

  • Broad scope of coverage makes this text an ideal companion for clinical laboratory science programs at various levels, including CLS/MT, CLT/MLT, medical laboratory assistant, and medical assisting, and reflects the taxonomy levels of the CLS/MT and CLT/MLT exams.
  • Detailed procedure guides and procedure worksheets on Evolve and in the ebook familiarize you with the exact steps performed in the lab.
  • Vivid, full-color illustrations depict concepts and applicable images that can be seen under the microscope.
  • An extensive number of certification-style, multiple-choice review questions are organized and coordinated under major topical headings at the end of each chapter to help you assess your understanding and identify areas requiring additional study.
  • Case studies include critical thinking group discussion questions, providing the opportunity to apply content to real-life scenarios.
  • The newest Entry Level Curriculum Updates for workforce entry, published by the American Society for Clinical Laboratory Science (ASCLS) and the American Society for Clinical Pathology (ASCP) Board of Certification Exam Content Outlines, serve as content reference sources.
  • Convenient glossary makes it easy to look up definitions without having to search through each chapter.
  • An Evolve companion website provides convenient access to animations, flash card sets, and additional review questions.
  • Experienced author, speaker, and educator Mary L. Turgeon is well known for providing insight into the rapidly changing field of clinical laboratory science.

Table of Contents

  • Cover Image
  • Title Page
  • Copyright
  • About the Author
  • Contributors
  • Reviewers
  • Dedication
  • Preface
  • Acknowledgments
  • Table of Contents
  • Part 1 Basic Laboratory Techniques
  • Chapter 1 Fundamentals of the Clinical Laboratory
  • CHAPTER OUTLINE
  • LEARNING Objectives
  • CLINICAL LABORATORY SCIENCE
  • CLINICAL LABORATORY SCIENCE AS A PROFESSION
  • CLINICAL LABORATORY SCIENCE PROGRAM ACCREDITATION
  • CLINICAL LABORATORY OVERVIEW
  • CLINICAL LABORATORY IMPROVEMENT AMENDMENTS OF 1988
  • LABORATORY DEPARTMENTS
  • HEALTH CARE ORGANIZATIONS
  • PRIMARY ACCREDITING ORGANIZATIONS
  • EXTERNAL GOVERNMENT LABORATORY ACCREDITATION AND REGULATION
  • ALTERNATE SITES OF TESTING
  • MEDICAL-LEGAL ISSUES
  • MEDICAL ETHICS
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • Chapter 2 Safety: Patient and Clinical Laboratory Practices
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • PATIENT SAFETY
  • SAFETY STANDARDS AND GOVERNING AGENCIES
  • THREATS TO LABORATORY SAFETY: SUPPLY CHAIN INTERRUPTION
  • AVOIDING TRANSMISSION OF INFECTIOUS DISEASES
  • HIGHLIGHTS OF SARS-CoV-2 LABORATORY BIOSAFETY
  • BLOODBORNE PATHOGENS
  • SAFE WORK PRACTICES FOR INFECTION CONTROL
  • OTHER PRACTICES NECESSARY FOR SAFETY ASSURANCE
  • PROTECTIVE TECHNIQUES FOR INFECTION CONTROL
  • SPECIMEN HANDLING AND SHIPPING REQUIREMENTS
  • PREVENTION OF DISEASE TRANSMISSION
  • ADDITIONAL LABORATORY HAZARDS
  • FINAL DECONTAMINATION OF WASTE MATERIALS
  • SAFETY AUDIT
  • BASIC FIRST-AID PROCEDURES
  • CASE STUDY
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 3 Quality Assessment and Quality Control in the Clinical Laboratory
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • THE VALUE OF QUALITY
  • PATIENT SPECIMENS
  • CLINICAL LABORATORY IMPROVEMENT AMENDMENTS
  • VOLUNTARY ACCREDITING ORGANIZATIONS
  • INTERNATIONAL STANDARDS FOR CLINICAL LABORATORIES
  • LEAN AND SIX SIGMA QUALITY SYSTEMS
  • QUALITY ASSURANCE
  • QUALITY ASSESSMENT—ERROR ANALYSIS
  • QUALITY ASSESSMENT—PHASES OF TESTING
  • PROFICIENCY TESTING
  • ALTERNATIVE ASSESSMENT
  • ACCURACY IN REPORTING RESULTS AND DOCUMENTATION
  • QUALITY CONTROL
  • CONTROL SPECIMENS
  • QUALITY ASSESSMENT DESCRIPTORS
  • QUALITY CONTROL STATISTICS
  • TOTAL ANALYTIC ERROR
  • MONITORING QUALITY CONTROL
  • OTHER QUALITY CONTROL RULES
  • TESTING OUTCOMES
  • CASE STUDY
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 4 The Microscope
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • DESCRIPTION
  • PARTS OF THE MICROSCOPE
  • CARE AND CLEANING OF THE MICROSCOPE
  • USE OF THE MICROSCOPE
  • OTHER TYPES OF MICROSCOPES (ILLUMINATION SYSTEMS)
  • DIGITAL MICROSCOPY
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 5 Systems of Measurement, Laboratory Equipment, and Reagents
  • CHAPTER CONTENTS
  • LEARNING OUTCOMES
  • SYSTEMS OF MEASUREMENT
  • INTERNATIONAL SYSTEM (SI SYSTEM)
  • LABWARE
  • LABORATORY BALANCES
  • LABORATORY CENTRIFUGES
  • LABORATORY REAGENT WATER
  • REAGENTS USED IN LABORATORY ASSAYS
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 6 Laboratory Mathematics and Solution Preparation
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • SIGNIFICANT FIGURES
  • EXPONENTS
  • DENSITY AND SPECIFIC GRAVITY
  • EXPRESSIONS OF SOLUTION CONCENTRATION
  • DILUTIONS
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 7 Basic and Contemporary Techniques in the Clinical Laboratory
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • PHOTOMETRY
  • ABSORBANCE SPECTROPHOTOMETRY
  • REFLECTANCE SPECTROPHOTOMETRY
  • NEPHELOMETRY
  • FLOW (CELL) CYTOMETRY
  • IMMUNOASSAYS
  • ALTERNATIVE LABELING TECHNOLOGIES
  • CHEMILUMINESCENCE
  • CHROMATOGRAPHY AND IMMUNOCHROMATOGRAPHY
  • ELECTROCHEMICAL METHODS
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 8 Laboratory Testing: From Point of Care to Total Automation
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • POINT-OF-CARE TESTING
  • NON–INSTRUMENT-BASED POINT-OF-CARE TESTING
  • HANDHELD POINT-OF-CARE TESTING EQUIPMENT
  • EMERGING PATIENT-CENTRIC TECHNOLOGIES
  • OVERVIEW OF INFORMATICS
  • COMMUNICATION AND NETWORK DEVICES
  • COMPUTER APPLICATIONS
  • OVERVIEW OF AUTOMATION
  • CASE STUDY
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Part 2 Basic Clinical Laboratory Specializations
  • Chapter 9 Phlebotomy: Collecting and Processing Patient Blood Specimens
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • QUALITY ASSESSMENT
  • Infection control
  • SPECIMEN COLLECTION
  • VENOUS BLOOD COLLECTION (PHLEBOTOMY)
  • SPECIMENS: GENERAL PREPARATION
  • CAPILLARY OR PERIPHERAL BLOOD COLLECTION BY SKIN PUNCTURE
  • CAPILLARY BLOOD COLLECTION
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 10 An Introduction to the Principles and Practice of Clinical Hematology
  • CHAPTER OUTLINE
  • Learning Objectives
  • PART ONE: HEMATOPOIESIS AND CELLULAR MATURATION
  • ERYTHROCYTES
  • LEUKOCYTES
  • LYMPHOCYTE MATURATION AND FUNCTION
  • THROMBOCYTES
  • PART TWO: HEMATOLOGY LABORATORY ASSESSMENTS
  • ADDITIONAL HEMATOLOGY PROCEDURES
  • PART THREE: ERYTHROCYTE DISORDERS
  • PART FOUR: Nonmalignant Leukocyte Disorders
  • PART FIVE: MALIGNANT LEUKOCYTE DISORDERS: LEUKEMIAS, LYMPHOID AND PLASMA CELL NEOPLASMS
  • PART SIX: OTHER MALIGNANT HEMATOLOGIC CATEGORIES
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 11 Hemostasis and Blood Coagulation
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • HEMOSTATIC MECHANISM
  • QUANTITATIVE PLATELET DISORDERS
  • QUALITATIVE PLATELET DISORDERS
  • COAGULATION
  • PATHWAYS FOR COAGULATION CASCADE
  • FIBRINOLYSIS
  • PROTECTIVE MECHANISMS AGAINST THROMBOSIS
  • TESTS FOR HEMOSTASIS AND COAGULATION
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 12 Renal Physiology and Urinalysis
  • CHAPTER CONTENTS
  • LEARNING OUTCOMES
  • OVERVIEW OF URINALYSIS
  • RENAL ANATOMY AND PHYSIOLOGY
  • COMPOSITION OF URINE
  • COLLECTION AND PRESERVATION OF URINE SPECIMENS
  • PHYSICAL PROPERTIES OF URINE
  • CHEMICAL TESTS IN ROUTINE URINALYSIS
  • MICROSCOPIC ANALYSIS OF URINE SEDIMENT
  • CONSTITUENTS OF URINE SEDIMENT
  • AUTOMATION IN URINALYSIS
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 13 Examination of Body Fluids and Miscellaneous Specimens
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • OVERVIEW OF BODY FLUIDS
  • CEREBROSPINAL FLUID
  • SEROUS FLUIDS: PERICARDIAL, PLEURAL, AND PERITONEAL
  • SYNOVIAL FLUID
  • SEMINAL FLUID
  • AMNIOTIC FLUID
  • SALIVA
  • AUTOMATED PLATFORMS IN BODY FLUID ANALYSIS
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 14 Introduction to the Principles and Practice of Clinical Chemistry
  • CHAPTER CONTENTS
  • LEARNING OUTCOMES
  • GLUCOSE AND GLUCOSE METABOLISM
  • DIABETES
  • ELECTROLYTES
  • ACID-BASE BALANCE AND BLOOD GASES
  • RENAL FUNCTION
  • URIC ACID
  • LIPIDS
  • CARDIOVASCULAR DISEASE
  • LIVER AND PANCREATIC TESTING
  • HORMONE ASSAYS
  • TUMOR MARKERS
  • THERAPEUTIC DRUG MONITORING
  • DRUGS OF ABUSE
  • AUTOMATION IN CLINICAL CHEMISTRY
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 15 New Frontiers in Molecular Diagnostics
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • PRINCIPLES OF GENETICS
  • THE GENETIC CODE
  • MOLECULAR TECHNIQUES
  • AMPLIFICATION METHODS
  • TARGET AMPLIFICATION METHODS
  • MOLECULAR ANALYSIS OF AMPLIFICATION PRODUCTS
  • HYBRIDIZATION ASSAYS
  • BLOTTING PROTOCOLS
  • MICROARRAYS
  • NEXT-GENERATION SEQUENCING TECHNOLOGY OR MASSIVELY PARALLEL SEQUENCING
  • MOLECULAR DIAGNOSTIC TESTING CLINICAL APPLICATIONS
  • INFECTIOUS DISEASES
  • GENETIC DISORDERS
  • HEMATOPATHOLOGY
  • SOLID TUMORS
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 16 Introduction to Medical Microbiology
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • INTRODUCTION TO MICROORGANISMS
  • CLASSIFICATION OF MICROORGANISMS: TAXONOMY
  • PROTECTION OF LABORATORY PERSONNEL AND GOOD LABORATORY PRACTICES
  • SPECIMENS FOR MICROBIOLOGICAL EXAMINATION
  • BASIC EQUIPMENT AND TECHNIQUES USED IN MICROBIOLOGY
  • IDENTIFICATION OF BACTERIA
  • URINE CULTURES
  • THROAT CULTURES
  • GENITOURINARY CULTURES
  • ENTERIC DISEASE
  • BLOOD CULTURES
  • WOUND OR SOFT TISSUE CULTURES
  • BACTERIAL DISEASE
  • QUALITY CONTROL IN THE MICROBIOLOGY LABORATORY
  • MYCOBACTERIA
  • TESTS FOR FUNGI (MYCOLOGY)
  • TESTS FOR PARASITES (PARASITOLOGY)
  • TESTS FOR VIRUSES (VIROLOGY)
  • AUTOMATION
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 17 Immunology and Serology
  • CHAPTER OUTLINE
  • LEARNING OBJECTIVES
  • OVERVIEW OF IMMUNOLOGY AND SEROLOGY
  • ANTIGENS AND ANTIBODIES
  • COMPLEMENT
  • BODY DEFENSES AGAINST MICROBIAL DISEASE
  • HYPERSENSITIVITY
  • TYPES OF ANTIGENS AND REACTIONS
  • CELLS AND CELLULAR ACTIVITIES OF THE IMMUNE SYSTEM
  • IMMUNOLOGIC DISORDERS
  • PRINCIPLES OF IMMUNOLOGIC AND SEROLOGIC METHODS
  • SPECIMENS FOR SEROLOGY AND IMMUNOLOGY
  • IMMUNOLOGIC AND SEROLOGIC TESTING FOR BACTERIAL AND VIRAL DISEASES
  • AUTOIMMUNE DISORDERS
  • TUMOR BIOMARKERS
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Chapter 18 Immunohematology and TransfusionMedicine
  • CHAPTER OUTLINE
  • LEARNING OUTCOMES
  • KEY TERMS
  • OVERVIEW OF BLOOD BANKING
  • BENEFITS AND REASONS FOR TRANSFUSION
  • WHOLE BLOOD, BLOOD COMPONENTS, AND DERIVATIVES FOR TRANSFUSION
  • BLOOD DONATION SAFETY FACTORS
  • BLOOD DONATION: DONOR SCREENING, COLLECTION, STORAGE, AND PROCESSING
  • BLOOD DONATION: DONORS, COLLECTION, STORAGE, AND PROCESSING
  • OTHER TYPES OF BLOOD DONATIONS
  • ANTIGENS AND ANTIBODIES IN IMMUNOHEMATOLOGY
  • ABO RED BLOOD CELL GROUP SYSTEM
  • RH RED BLOOD CELL GROUP SYSTEM
  • OTHER BLOOD GROUP SYSTEMS
  • ANTIHUMAN GLOBULIN REACTION
  • COMPATIBILITY TESTING: DEFINITION AND GENERAL CONSIDERATIONS
  • MOLECULAR-BASED TRANSFUSION TESTING
  • ADVERSE EFFECTS OF TRANSFUSION
  • HEMOLYTIC DISEASE OF THE FETUS AND NEWBORN
  • AUTOMATED TESTING TECHNOLOGY AND SYSTEMS
  • CASE STUDIES
  • REFERENCES
  • BIBLIOGRAPHY
  • REVIEW QUESTIONS (ANSWERS IN APPENDIX A)
  • STUDENT PROCEDURE WORKSHEET
  • Appendix A Answers to Review Questions and Case Studies
  • Appendix B AMA Recognized Disease/Organ Panels
  • Appendix C Periodic Table
  • Appendix D Overview of COVID-19
  • Appendix E Molecular Testing Methods
  • Appendix F Quick Calculations and Adult Reference Values
  • Glossary
  • Index

Product details

  • No. of pages: 704
  • Language: English
  • Copyright: © Elsevier 2022
  • Published: September 14, 2022
  • Imprint: Elsevier
  • Paperback ISBN: 9780323829342
  • eBook ISBN: 9780323832212

About the Author

Mary Turgeon

Affiliations and Expertise

Associate Professor (Adjunct), University of Texas Medical Branch, Galveston, Texas; Clinical Laboratory Education Consultant, Mary L. Turgeon and Associates, Boston, Massachusetts; St. Petersburg, Florida

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