Clinical Immunology: Principles and Practice

3rd Edition

Expert Consult: Online and Print

Authors: Robert Rich Thomas Fleisher William Shearer Harry Schroeder Anthony Frew Cornelia Weyand
Hardcover ISBN: 9780323044042
Imprint: Mosby
Published Date: 15th April 2008
Page Count: 1616

Description

Written and edited by international leaders in the field, this book has, through two bestselling editions, been the place to turn for authoritative answers to your toughest challenges in clinical immunology. Now in full color and one single volume, Clinical Immunology: Principles and Practice, 3rd Edition brings you the very latest immunology knowledge -- so you can offer your patients the best possible care. The user-friendly book and the fully searchable companion website give you two ways to find the answers you need quickly... and regular online updates keep you absolutely current.

Key Features

  • Leading international experts equip you with peerless advice and global best practices to enhance your diagnosis and management of a full range of immunologic problems.
  • A highly clinical focus and an extremely practical organization expedite access to the answers you need in your daily practice.

Table of Contents

PART 1: Fundamental Principles of the Immune Response

1 The human immune response
2 Organization of the immune system
3 Innate immunity
4 Antigen receptor genes, gene products, and co-receptors
5 The major histocompatibility complex
6 Antigens and antigen processing
7 Antigen-presenting cells and antigen presentation
8 B-cell development and differentiation
9 T-cell development
10 Cytokines and cytokine receptors
11 Chemokines and chemokine receptors
12 Lymphocyte adhesion and trafficking
13 T-cell activation and tolerance
14 Programmed cell death in lymphocytes

PART 2: Host Defense Mechanisms and Inflammation

15 Immunoglobulin function
16 Regulatory T cells
17 Helper T-cell subsets and control of the inflammatory response
18 Cytotoxic lymphocyte function and natural killer cells
19 Host defenses at mucosal surfaces
20 Complement and complement deficiencies
21 Phagocytes and phagocyte deficiencies
22 Mast cells, basophils and mastocytosis
23 Eosinophils and eosinophilia

PART 3: Infection and Immunity

24 Immune response to extracellular bacteria
25 Immune responses to intracellular bacteria
26 Immune responses to spirochetes
27 Immune responses to viruses
28 I mmune responses to protozoans
29 Immune responses to helminths

PART 4: Immunologic Deficiencies

30 Evaluation of the immunodeficient patient
31 Infections in the immunocompromised host
32 Development of the fetal and neonatal immune system
33 Aging and the immune system
34 Primary antibody deficiencies
35 Primary T-cell immunodeficiencies
36 Inherited disorders of IFN-γ-, IFN-α/β-, and NF-κB-mediated immunity
37 HIV infection and acquired immunodeficiency syndrome
38 Immunodeficiency due to congenital, metabolic, infectious,
surgical, and environmental factors

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Details

No. of pages:
1616
Language:
English
Copyright:
© Mosby 2008
Published:
Imprint:
Mosby
Hardcover ISBN:
9780323044042

About the Author

Robert Rich

Affiliations and Expertise

Professor of Medicine and Microbiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA

Thomas Fleisher

Affiliations and Expertise

Adjunct Professor of Pediatrics, USUHA, Chief, Department of Laboratory Medicine, NIH Clinical Center, Natonal Institutes of Health, Bethesda MD, USA

William Shearer

Affiliations and Expertise

Professor of Pediatrics and of Pathology and Immunology, Baylor College of Medicine, Chief, Allergy and Immunology Service, Texas Children’s Hospital, Houston, TX, USA

Harry Schroeder

Affiliations and Expertise

Professor of Medicine, Microbiology, and Genetics

Anthony Frew

Affiliations and Expertise

Professor of Allergy and Respiratory Medicine, Department of Respiratory Medicine, Brighton General Hospital, Brighton, UK

Cornelia Weyand

Affiliations and Expertise

Professor of Medicine, Stanford University School of Medicine, Department of Medicine: Immunology and Rheumatology, Stanford, CA, USA

Reviews

"…the basics of immunology are rapidly expounded with summaries, tables, and diagrams providing a depth of information on immunological mechanisms in an eye-catching format... The editors and contributors are to be congratulated on this work and I would suggest it would be a valuable reference for those working in the field." - British Society for Immunology, May 2009