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Clinical Immunobiology
1st Edition, Volume 3 - January 1, 1976
Editors: Fritz H. Bach, Robert A. Good
Language: English
eBook ISBN:9781483216348
9 7 8 - 1 - 4 8 3 2 - 1 6 3 4 - 8
Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual. This volume is composed of 21 chapters and begins with a…Read more
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Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual. This volume is composed of 21 chapters and begins with a presentation of the background and issues to which clinical tests would be applied. The succeeding chapters outline the methodological procedures used in the analyses. Other chapters present some examples of the kinds of data that can be generated with the procedures used and provide guidelines for interpretation of the tests. The remaining chapters discuss the value of the immunological test procedures in differential diagnosis and analysis of diseases. These chapters also explore the usefulness of these procedures in prognosis of disease and the consequences of immunological manipulation undertaken for treatment or prevention of disease. This book will be of great value to clinical immunobiologists, biochemists, and researchers.
List of Contributors
Preface
Contents of Previous Volumes
Evaluation of the Immunoglobulins
I. Introduction
II. Techniques
III. Results
IV. Summary
References
Electrophoresis and Immunoelectrophoresis in the Evaluation of Homogeneous Immunoglobulin Components
I. Introduction
II. Homogeneous Proteins in Disease States
III. Techniques for Characterization and Quantitation of Homogeneous Immunoglobulin Components
IV. Evaluation of Test Results
V. Conclusions
References
Serum Concentrations of IgG Subclasses
I. Introduction
II. Quantitative Determination of IgG Subclasses
III. IgG Subclass Concentrations in Sera of Normal Individuals
IV. Subclass Levels in Sera of Patients with Increased Concentrations of Total IgG
V. IgG Subclasses in Primary Immunodeficiency Diseases
VI. IgG Subclasses after Bone Marrow Transplantation in Severe Combined Immunodeficiency
References
Imbalances of the κ/λ Ratio of Human Immunoglobulins
I. Introduction
II. Methods for Detection of Human Immunoglobulin Light-Chain Imbalances
III. Analyses of Normal and Pathological Sera
IV. Conclusions
References
Metabolism of Immunoglobulins
I. Introduction
II. Methods Used in Immunoglobulin Turnover Studies
III. Metabolism of Immunoglobulins in Normal Individuals