Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies

1st Edition - August 7, 2018

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  • Editor: Sorin Hostiuc
  • Paperback ISBN: 9780128137642
  • eBook ISBN: 9780128137659

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Description

Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students. As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource.

Key Features

  • Provides practical analysis of the ethical issues raised by cutting-edge techniques and recent advances in prenatal and reproductive genetics
  • Contains contributions from leading bioethicists and clinicians who offer a global, holistic perspective on applied challenges and moral questions relating to genetic and genomic reproductive technology
  • Discusses preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, ethical issues, and more

Readership

Active researchers, basic and translational scientists, clinicians, and students in the areas of human genetics, medical genetics, genomics, reproductive medicine, gynecology, obstetrics, andrology, embryology, prenatal testing, and genetic testing; genetic counselors; bioethicists; fertility specialists; lawmakers and regulators; medical students and residents; pharmacologists

Table of Contents

  • 1. Genomic Editing—From Human Health to the “Perfect Child”

    2. Ethics of Mitochondrial Gene Replacement Therapy

    3. Reproductive Technologies Used by Same Gender Couples

    4. Ethical Issues Raised by Multiparents

    5. Revisiting the Nondirective Principle of Genetic Counseling in Prenatal Screening

    6. Sex Selection, Gender Selection, and Sexism

    7. The Impact of Big Data on Beginning of Life Issues

    8. The Moral Status of the Embryo From the Standpoint of Social Perceptions

    9. Fetal Reduction

    10. Stem Cell Therapies for Neurodegenerative Disorders. An Ethical Analysis

    11. Predictive Genetic Testing in Multifactorial Disorders

    12. Whole-Genome Sequencing as a Method of Prenatal Genetic Diagnosis

    13. Noninvasive Prenatal Genetic Diagnosis

    14. Prenatal Testing in Low-Risk Populations: A US Perspective

    15. Using Genetics for Enhancement (Liberal Eugenics)

    16. Should Incidental Findings Arising From Prenatal Testing be Reported Indiscriminately to Patients?

    17. Third Party Sharing of Genetic Information

Product details

  • No. of pages: 431
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: August 7, 2018
  • Imprint: Academic Press
  • Paperback ISBN: 9780128137642
  • eBook ISBN: 9780128137659

About the Editor

Sorin Hostiuc

Sorin Hostiuc, MD, PhD, is an Assistant Professor in the Department of Legal Medicine and Bioethics at Carol Davila Medicine and Pharmacy University, Bucharest, Romania, and Senior Physician at the National Institute of Legal Medicine Bucharest, Romania. Dr. Hostiuc has written extensively on such topics as informed consent, research ethics, history of medical ethics, and reproductive ethics, with over 100 published articles in PLOS ONE, Journal of Translational Medicine, and Frontiers in Neuroscience among other journals. He has also published three monographs in the Romanian language dealing with bioethical issues, including Ethics of Scientific Research, Ethics of Scientific Publishing, and Informed Consent, as well as a book chapter on the current state of bioethics in Bioethics – A Global Discourse (LIT Verlag Publishers, 2016). Dr. Hostiuc received his PhD in medicine and his MD, from Carol Davila Medicine and Pharmacy University. He also completed a certification in research ethics at the Icahn School of Medicine at Mount Sinai, New York, USA.

Affiliations and Expertise

Assistant Professor, Department of Legal Medicine and Bioethics, Carol Davila Medicine and Pharmacy University, Bucharest, Romania, and Senior Physician, National Institute of Legal Medicine Bucharest, Romania

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