Key Features

  • Full coverage of clinical chemistry from experts in the field gives you a solid foundation for transferring from theory to practice.
  • Clear explanations and user-friendly features make this a textbook that you can continue to use as a reference on the job.
  • Key terms listed at the beginning of each chapter help you master relevant vocabulary.
  • Section objectives highlight the most important content and provide goals for each chapter.

Table of Contents

Part I: Laboratory Techniques and Laboratory Management

1. Basic Laboratory Principles and Techniques

2. Spectral Techniques

3. Chromatography and Mass Spectrometry: Theory, Practice, and Instrumentation

4. Chromatographic Techniques

5. Laboratory Analysis of Hemoglobin Variants NEW!

6. Electrophoresis

7. Immunological Reactions

8. Immunochemical Techniques

9. Principles for Competitive-Binding Assays

10. Laboratory Approaches to Serology Testing NEW!

11. Measurement of Colligative Properties

12. Electrochemistry: Principles and Measurement

13. Molecular Diagnostics

14. Therapeutic Drug Monitoring

15. Clinical Enzymology

16. Protein Isoforms: Isoenzymes and Isoforms

17. Interferences in Chemical Analysis

18. Sources and Control of Preanalytical Variation

19. Laboratory Management

20. Laboratory Automation

21. Point-of-Care (Near-Patient) Testing

22. Laboratory Information Systems

23. Laboratory Statistics

24. Reference Intervals and Clinical Decision Limits

25. Quality Control in the Clinical Chemistry Laboratory

26. Evaluation of Methods

Part II: Physiology and Pathophysiology

27. Basic Biochemistry

28. Physiology of Body Water and Electrolytes

29. Acid-Base Control and Acid-Base Disorders

30. Renal Function

31. Liver Function

32. Viral Hepatitis: Diagnosis and Monitoring NEW!

33. Bone Disease

34. The Pancreas: Function and Chemical Pathology

35. Gastrointestinal Function

36. Cardiac and Muscle Disease

37. Coronary Artery Disease: Lipid Metabolism

38. Diabetes

39. Iron, Porphyrin, and Bilirubin Metabolism

40. Hemoglobin

41. Human Nutrition

42. Trace Metals

43. Vitamins<


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About the authors

Lawrence Kaplan

Affiliations and Expertise

Director, Clinical Chemistry, Bellevue Hospital; Clinical Professor, Pathology, New York University, New York, NY

Amadeo Pesce

Affiliations and Expertise

Professor, Department of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati, Cincinnati, OH; Laboratory Director, Adams County Hospital, West Union, OH; Laboratory Director, Drake Center, Cincinnati, OH