Clinical Cases in Uveitis

Differential Diagnosis and Management

1st Edition - December 9, 2020
Editors: Harpal Sandhu, Henry J. Kaplan
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 6 9 5 4 1 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 6 9 5 4 2 - 8

Intraocular inflammation is particularly difficult to diagnose and treat, often resembling a complex puzzle of patient history, symptoms, imaging, and laboratory test results.… Read more

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Intraocular inflammation is particularly difficult to diagnose and treat, often resembling a complex puzzle of patient history, symptoms, imaging, and laboratory test results. Clinical Cases in Uveitis: Differential Diagnosis and Management is a unique, case-based resource designed to help you navigate the range of challenging manifestations and presentations that often mimic other diseases. More than 90 real-world uveitis cases are presented in a highly templated, easy-to-follow format, along with step-by-step guidance on the right patient questions, assessment, differential diagnosis, testing, management, and follow-up care.

Cover image
Title page
Table of Contents
Copyright
Dedication
List of Contributors
Preface
Acknowledgments
Chapter 1. Introduction to Uveitis
Abstract
References
Chapter 2. Approach to Diagnostic Testing
Abstract
Introduction
Anterior Uveitis
Intermediate Uveitis
Panuveitis
Retinal Vasculitis
Scleritis
Chapter 3. Approach to Therapy
Abstract
Introduction
General Guidelines: Local Versus Systemic Therapy
Systemic Therapy: Corticosteroids and Systemic Immunomodulatory Therapy
Local Injectable Therapies
Chapter 4. First Episode of Acute Iritis
Abstract
History of Present Illness (HPI)
Further Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Management
Follow-up
Management
Key Points
Chapter 5. Keratouveitis Secondary to Retained Lens Fragments
Abstract
History of Present Illness (HPI)
Further Questions to Ask
Assessment
Differential Diagnosis
Testing
Diagnosis
Management
Follow-up
Key Points
Chapter 6. Cytomegalovirus (CMV) Anterior Uveitis
Abstract
History of Present Illness (HPI)
Further Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 7. Chronic Anterior Uveitis
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Management
Follow-up
Management
Key Points
Chapter 8. Hypopyon Uveitis
Abstract
History of Present Illness (HPI)
Past Medical History (PMH)
Further Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Working Diagnosis
Management
Further Follow-up
Diagnosis
Management
Extended Follow-up
Key Points
Chapter 9. Herpetic Keratitis and Iritis
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management
Further Follow-up
Key Points
Chapter 10. Juvenile Idiopathic Arthritis (JIA)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up Care
Follow-up
Key Points
Chapter 11. Tubulointerstitial Nephritis and Uveitis Syndrome (TINU)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 12. Blau-Jabs Syndrome (Granulomatous Arthritis, Dermatitis and Uveitis)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 13. Postoperative Uveitis
Abstract
History of Present Illness (HPI)
Past Ocular History
Past Medical History
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Working Diagnosis
Testing
Further Follow-up
Diagnosis
Key Points
Chapter 14. Bilateral Pigment Dispersion
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management
Further Follow-up
Key Points
Chapter 15. Episcleritis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 16. Refractory Scleritis in an Older Woman
Abstract
History of Present Illness (HPI)
Eye-Related Medications
Further Questions to Ask
Assessment
Differential Diagnosis
Management
Follow-up
Assessment
Management
Follow-up
Key Points
Chapter 17. Necrotizing Scleritis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 18. Ebola Uveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis for Panuveitis
Working Diagnosis
Further Testing
Management
Follow-up
Key Points
Chapter 19. Iris Mass and Panuveitis in a Child
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Final Diagnosis
Key Points
Diagnostic Algorithm
Chapter 20. Toxic Anterior Segment Syndrome
Abstract
History of Present Illness (HPI)
Assessment
Differential Diagnosis
Testing
Working Diagnosis
Management
Follow-up
Diagnosis
Management
Further Follow-up
Key Points
Chapter 21. Pars Planitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 22. Lyme Disease
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 23. Amyloidosis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 24. Retinoblastoma
Abstract
History of Present Illness
Questions to Ask
Testing
Assessment
Differential Diagnosis
Working Diagnosis
Further Testing
Management
Follow-up
Key Points
Chapter 25. Intraocular Foreign Body and Uveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 26. Eales Disease
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Laboratory and Imaging Workup
Management
Follow-up
Management Algorithm
Key Points
Chapter 27. Posterior Scleritis
Abstract
History of Present Illness
Questions to Ask
Assessment
Systemic Disease Associations
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 28. Multifocal Choroiditis with Panuveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Assessment
Management
Follow-up
Key Points
Chapter 29. Common Variable Immunodeficiency with Granulomatous Panuveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Key Points
Chapter 30. Sarcoidosis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 31. Punctate Inner Choroidopathy (PIC)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Follow-up Examination
Follow-up Assessment
Working Diagnosis 2
Management
Follow-up
Key Points
Chapter 32. Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 33. Multiple Evanescent White Dot Syndrome (MEWDS)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 34. Serpiginous Choroidits
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up Care
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 35. Relentless (Ampiginous) Placoid Chorioretinitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 36. Uveitis with Subretinal Fibrosis Syndrome (USF)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Follow-up Examination
Working Diagnosis 2
Follow-up Management
Follow-up
Final Diagnosis
Key Points
Chapter 37. Birdshot Retinochoroidopathy (BRC)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 38. Autoimmune Retinopathy
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Further Testing
Working Diagnosis
Testing
Management
Follow-up
Diagnostic Algorithm
Key Points
Chapter 39. Melanoma-Associated Retinopathy
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 40. Hemorrhagic Occlusive Retinal Vasculitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 41. Syphilitic Posterior Placoid Chorioretinitis
Abstract
History of Present Illness
Past Medical History
Examination Findings
Questions to Ask
Assessment
Differential Diagnosis
Testing
Management
Follow-up
Diagnosis
Management
Further Follow-up
Diagnostic Algorithm for Ocular Syphilis
Key Points
Chapter 42. Syphilitic Uveitis and Outer Retinopathy
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Systemic Workup
Management
Follow-up
Key Points
Chapter 43. Tuberculous Uveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 44. Diffuse Unilateral Subacute Neuroretinitis (DUSN)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 45. Exudative Retinal Detachment
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management
Follow-up #2
Management
Follow-up #3
Management
Follow-up #4
Key Points
Chapter 46. Endogenous Endophthalmitis
Abstract
History of Present Illness
Questions to Ask the Primary Team
Assessment
Differential Diagnosis
Management
Follow-up
Key Points
Chapter 47. Acute Retinal Necrosis (ARN)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 48. Progressive Outer Retinal Necrosis (PORN)
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 49. Toxoplasmosis
Abstract
History of Present Illness
Further Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management
Management Algorithm
Key Points
Chapter 50. Severe, Atypical Toxoplasmosis
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Management
Follow-up
Assessment
Differential Diagnosis
Working Diagnosis
Management
Follow-up #2 (3 Weeks Post-presentation)
Assessment
Final Diagnosis
Key Points
Chapter 51. Toxocariasis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 52. Systemic Lupus Erythematosus with Retinal Vasculitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 53. Cytomegalovirus (CMV) Retinitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Working Diagnosis
Management
Follow-up
Key Points
Chapter 54. Vogt-Koyanagi-Harada Disease
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Follow-up Assessment
Working Diagnosis 2
Management
Follow-up
Key Points
Chapter 55. Neuroretinitis
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Diagnosis
Management
Follow-up
Key Points
Chapter 56. Acute Exudative Polymorphous Vitelliform Maculopathy
Abstract
History of Present Illness (HPI)
Past Medical History
Further Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Management
Follow-up
Diagnosis
Management
Key Points
Chapter 57. MEK Inhibitor-Associated Retinopathy (MEKAR)
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Testing
Working Diagnosis
Management
Follow-up
Key Points
Chapter 58. Immune Checkpoint Inhibitor-Induced Panuveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management
Key Points
Chapter 59. Cysticercosis
Abstract
History of Presenting Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 60. Leptospirosis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management
Further Follow-up
Key Points
Chapter 61. Granulomatosis with Polyangiitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 62. Frosted Branch Angiitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 63. Susac Syndrome (Retinal Vasculitis, Hearing Loss, and Encephalopathy)
Abstract
History of Present Illness
Questions to Ask the Family and Management Team at the Referring Hospital
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 64. IRVAN Syndrome (Idiopathic Retinal Vasculitis, Aneurysms and Neuroretinitis)
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
References
Chapter 65. Retinal Degeneration with Coats-Like Fundus
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Final Diagnosis
Key Points
Chapter 66. Congenital Zika Syndrome
Abstract
History of Present Illness
Initial Examination at 4 Months
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 67. West Nile Retinopathy
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 68. Dengue Retinopathy
Abstract
History of Present Illness
Ocular Examination
Questions Asked
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Fundus Fluorescein Angiography
Spectral Domain Optical Coherence Tomography
Management
Follow-up
Key Points
Chapter 69. Primary Vitreoretinal Lymphoma (PVRL)
Abstract
History of Present Illness
Questions to Ask
Differential Diagnosis
Working Diagnosis
Testing
Follow-up
Management
Further Follow-up
Key Points
Chapter 70. Leukemia Metastatic to the Retina
Abstract
History of Present Illness (HPI)
Further Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Further Testing
Management
Follow-up #1
Management
Follow-up #2
Management
Follow-up #3
Diagnosis
Management
Follow-up #4
Key Points
Chapter 71. New-Onset Macular Edema
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management
Follow-up #2
Management
Follow-up #3
Management
Follow-up #4
Eye-Related Medications
Assessment
Management
Follow-up #5
Management Algorithm
Key Points
Chapter 72. Cystoid Macular Edema After Infectious Uveitis
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Management
Follow-up
Management
Key Points
Chapter 73. Polypoidal Choroidal Vasculopathy (PCV) in SLE
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 74. Chronic Hypotony with Metastatic Melanoma and Checkpoint Inhibitor
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up Evaluation
Follow-up Assessment
Management
Working Diagnosis #2
Management
Follow-up
Key Points
Chapter 75. Uveitic Cataract
Abstract
History of Present Illness (HPI)
Further Questions to Ask
Assessment
Management
Follow-up
Assessment
Management
Further Follow-up
Management Algorithm
Key Points
Chapter 76. Advanced, Undetected Steroid-Induced Glaucoma
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Chapter 77. Corneal Decompensation After Dexamethasone Implant
Abstract
History of Present Illness (HPI)
Questions to Ask
Assessment
Management
One-Hour Follow-up
Management
Further Follow-up
Management
Key Points
Chapter 78. Epiretinal Membrane and Panuveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Management
Follow-up
Key Points
Chapter 79. Globe Perforation After Sub-Tenon's Injection
Abstract
History of Present Illness (HPI)
Past Ocular History (POH)
Further Questions to Ask
Assessment
Management
Follow-up
Assessment
Management
Follow-up #2
Management
Follow-up #3
Key Points
Chapter 80. Sterile Endophthalmitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Management
Follow-up
Working Diagnosis
Management
Further Follow-up
Key Points
Chapter 81. Contralateral Retinitis in a Patient on Systemic Immunomodulatory Therapy
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Management Algorithm
Key Points
Chapter 82. Rhegmatogenous Retinal Detachment in Intermediate Uveitis
Abstract
History of Present Illness
Questions to Ask
Assessment
Differential Diagnosis
Working Diagnosis
Testing
Management
Follow-up
Key Points
Index

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Henry J. Kaplan