Clinical Case Studies on Medication Safety

Clinical Case Studies on Medication Safety

1st Edition - January 16, 2023

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  • Editor: Yaser Mohammed Al-Worafi
  • Paperback ISBN: 9780323988025

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Description

Clinical Case Studies on Medication Safety provides real and simulated scenarios about safety issues related to medication, including Adverse Drug Reactions (ADRs), medication errors, and Drug Related Problems (DRPs). The book explains real-life case management, including details about adverse drug reactions, mistakes during drug administration, drug avoidance, and drug-drug interactions with a goal of improving patient care. With over 150 case studies, including cases from alternative medicine and traditional medicine, this book will help medical and health sciences educators, students, healthcare professionals, and other readers apply their knowledge and skills to solve cases for better patient care.

Key Features

  • Includes real and simulated case studies about drug safety issues
  • Aids medical students and practitioners to improve their case solving skills
  • Contains more than 150 case studies with questions and key answers

Readership

Medical and health sciences educators & students, health care professionals (Physicians, dentists, Pharmacists, nurses, technicians) and researchers; Professionals working in Pharmacovigilance centers

Table of Contents

  • I: Introduction to membrane-less organelles and biomolecular condensates
    1. Biophysical principles of liquideliquid phase separation
    2. Major structural features of membraneless organelles
    3. Biochemical and structural biology aspects of liquideliquid phase separation: protein side of liquideliquid phase separation, membrane-less organelles, and biomolecular condensates
    4. Biochemical and structural biology aspects of liquideliquid phase separation: an interplay between proteins and RNA
    5. Liquideliquid phase separation and biomolecular condensates in cell quiescence
    6. Multiphase complex droplets
    7. Techniques for the detection and analysis of LLPS and MLOs
    8. Guidelines for experimental characterization of LLPS in vitro
    9. Liquideliquid phase separation at the origins of life

    II. Biology of membrane-less organelle
    10. Known types of membrane-less organelles and biomolecular condensates
    11. Active regulation mechanisms of LLPS and MLOs biogenesis
    12. Interactions and interplay of MLOs with classical membrane-bound organelles
    13. Intrinsically disordered regions: a platform for regulated assembly of biomolecular condensates
    14. MLOs and control of metabolic pathways
    15. LLPS and regulation of transmembrane signaling
    16. Phase separation in chromatin-based intranuclear processes
    17. MLOstasis: liquideliquid phase separation and biomolecular condensates in cell competition, fitness, and aging
    18. Stress, membrane-less organelles, and liquideliquid phase separation
    19. Roles of phase separation and condensates in autophagy
    20. Liquideliquid phase in anhydrobiosis
    21. Plant biomolecular condensates
    22. Droplets of life: role of phase separation in virus replication and compartmentalization

    III. Pathological roles of LLPS
    23. Liquideliquid phase separation in neurodegenerative diseases
    24. Emerging roles of organelles in cancer progression
    25. Liquideliquid phase separation, membrane-less organelles, and biomolecular condensates in cardiovascular disease
    26. Phase separation and infectious diseases

Product details

  • No. of pages: 350
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: January 16, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780323988025

About the Editor

Yaser Mohammed Al-Worafi

Prof. Yaser Mohammed Al-Worafi is a Professor of Clinical Pharmacy at the College of Pharmacy, University of Science and Technology of Fujairah, UAE (Previously known as Ajman University). He graduated with a bachelor's degree in Pharmacy (BPharm) from Sana’a University, Yemen and obtained a Master and PhD degree in Clinical Pharmacy from the Universiti Sains Malaysia (USM), Malaysia. He has more than 20 years experience in education, practice and research in Yemen, Saudi Arabia, United Arab Emirates and Malaysia. He has held various academic and professional positions including Deputy Dean for Medical Sciences College; PharmD program director, Head of Clinical Pharmacy/Pharmacy Practice department; Head of Teaching & learning committee, Head of Training Committee, head of the curriculum committee and other committees. He has authored over 100 peer-reviewed papers in international journals, and book chapters and edited more than 10 books by Elsevier, Springer, Taylors & Francis, USA. Prof.Yaser has supervised/co-supervised many PhD, Master, PharmD and B-Pharm students. He is a reviewer for eight recognized international peer-reviewed journals. Prof. Yaser prepared, designed, and wrote many pharmacy programs for many universities including Master of Clinical Pharmacy/Pharmacy Practice program; PharmD program and BPharm program; internship/clerkships for Master, PharmD and BPharm programs; more than 30 courses related to Clinical Pharmacy, Pharmacy Practice, Social Pharmacy and Patients care.

Affiliations and Expertise

Professor of Clinical Pharmacy, College of Pharmacy, University of Science and Technology of Fujairah, Fujairah, United Arab Emirates; Deputy Dean and Professor, College of Medical Sciences, Azal University for Human Development, Sana’a, Yemen.

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  • Waqar l. Tue Oct 04 2022

    Best one

    Best work