Circadian Rhythms and the Human

ForewordChapter 1 Introduction and Methods of Study Rhythms in Living Organisms Definition of Terms Detection of Rhythms Analysis of Rhythms Exogenous and Endogenous Rhythms Establishing the Endogeneity of Rhythms; SummaryChapter 2 The Circadian Rhythm of Deep Body Temperature Methods of Measurement The Nychthemeral Rhythm The Endogenous Component Exogenous Effects upon the Temperature Rhythm The Interaction between Exogenous and Endogenous Influences Origin of the Rhythm Implications and UsefulnessChapter 3 Cardiovascular, Respiratory, Metabolic and Gastrointestinal Rhythms I Cardiovascular system: Continuous Monitoring Blood Pressure Pulse Rate Other Cardiovascular Variables The Causal Nexus between Cardiovascular Variables II Respiratory System: Oxygen Consumption, Respiratory Frequency and Blood Gas Partial Pressures Mechanical Factors The Effect of Exercise at Different Times of Day The Causal Nexus III Metabolic and Gastrointestinal Rhythms: Metabolic Rhythms Gastrointestinal RhythmsChapter 4 The Kidney and Hormones Affecting it Endogenous and Exogenous Components Possible Origins of Renal RhythmicityChapter 5 Sleep and Wakefulness Studying the Sleep-Wakefulness Rhythm Results of Sleep-Wake Fullness Studies Inferences from Isolation Experiments Sleep StagesChapter 6 Rhythms in Mental Performance Problems Associated with Psychometric Testing Assessment of Mental Performance Rhythms Results on a Nychthemeral Routine The Causal Nexus and Performance Rhythms SummaryChapter 7 The Endocrine System Problems Cortisol, Adrenocorticotrophic Hormone and Corticotrophin Releasing Factor Growth Hormone Other Hormones Some General ProblemsChapter 8 Rhythms in the Infant and the Aged I The Infant: Results Inferences and Speculations II The AgedChapter 9 Time-Zone Transitions Introduction Results Differences Produced by Time-Zone Transitions Entrainment by Partition: Masking Consequences of Repeated Time-Zone Transitions Advice to TravelersChapter 10 Shiftwork Introduction Some Problems in Assessing Implications of Shift Work Complaints Associated with Shift Work Performance during Shift Work Results and Problems with Other Shift Systems Permanent Shift Workers and Adaptability to Shift Work ConclusionsChapter 11 Clinical Implications Normal Values and Circadian Rhythms Autorhythmometry Changed Circadian Rhythms in Illness The Effects of Time of Drug Administration—Chronotherapy Implications for the Availability of Medical Services ConclusionsChapter 12 Circadian Rhythm Mechanisms A Hierarchy of Rhythms and the Causal Nexus between Them How Many Clocks? Properties of the Endogenous Oscillator(s) Entrainment and Zeitgeber Zeitgeber in Man Appendix Statistical Analysis of Rhythms Glossary Index