Chronic Pancreatitis - ECAB - 1st Edition - ISBN: 9788131225097, 9788131231883

Chronic Pancreatitis - ECAB

1st Edition

Editors: Pramod Garg
Print ISBN: 9788131225097
eBook ISBN: 9788131231883
Imprint: Elsevier India
Published Date: 26th March 2010


Chronic pancreatitis (CP) is defined as a continuous or recurrent inflammatory disease of the pancreas characterized by progressive and irreversible morphological changes. It typically causes pain and permanent impairment of pancreatic function. In chronic pancreatitis, areas of focal necrosis are typically associated with perilobular and intralobular fibrosis of the parenchyma, by stone formation in the pancreatic duct, and by the development of pseudocysts. Late in the course of the disease a progressive loss of endocrine and exocrine function occurs.

In the past, chronic pancreatitis was considered to be mostly associated with chronic alcohol abuse. During the past 2 decades idiopathic chronic pancreatitis and, moreover, hereditary pancreatitis have been recognized as distinct disease entities. Usually the diagnosis is made by a combination of imaging procedures such as ultrasound and endoscopic retrograde cholangiopancreatography, and exocrine and endocrine function tests. Therapy is presently restricted to symptom control for the lack of a causal treatment strategy. Thirty to sixty percent of all patients develop disease-associated complications such as persistent pain, strictures of the common bile duct, or pancreatic duct stones that may require either endoscopic or surgical treatment.

Chronic pancreatitis is a difficult condition to live with as well as to treat. Optimal care needs to be carried out in a multidisciplinary environment that can address both the physical and psychological aspects of the disease. It is commonly seen in alcohol-dependent individuals, but many other groups of individuals suffer with irreversible inflammatory destruction of the pancreas. Abdominal pain is the predominant feature and pain specialists are an important part of any pancreatic team. Exocrine and endocrine failure are addressed by appropriate nutrition with supplements and insulin, whilst the complications that are seen over time, may requi

Table of Contents

Epidemiology of Chronic Pancreatitis

Chronic Pancreatitis: Definition and Classification

Chronic Pancreatitis: Perspective from Northern India

Chronic Pancreatitis: A South Indian Perspective

Etiopathogenesis of Chronic Pancreatitis

Diagnosis and Investigations in Chronic Pancreatitis

Chronic Pancreatitis: Medical Management

Pancreatic Enzyme Replacement Therapy in Chronic Pancreatitis

Surgical Management of Chronic Pancreatitis: Current Role of Surgical Therapy

Endotherapy in Chronic Pancreatitis

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About the Editor

Pramod Garg

Affiliations and Expertise

Associate Professor Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.