Chromatin and Chromosome Structure

Chromatin and Chromosome Structure consists of chapters that reflect a 1975 seminar course and the reported observations after the session. The seminar is organized for the benefit of both faculty and students in the Biology Ph.D. Program of the City University of New York.
This book begins with a presentation of the conformational studies of histones. It then describes the histone-DNA interactions and the subunits isolated either from chromatin or from nuclei. It also explains the post-synthetic modifications of histone structure. Furthermore, the book talks about the chemistry and function of nuclear nonhistone proteins, low molecular weight nuclear RNA, and polytene chromosome structure. The regulation of gene expression in chick oviduct model system and the main features of lampbrush chromosomes are shown as well. Aside from the students and faculty of the above-mentioned university, this compilation will be invaluable as well to other undergraduate and graduate students; professors; and researchers. It will also be a good reference to those who are specializing in chromatin and chromosome studies.

List of Contributors

Preface

Nomenclature for Histone Fractions

Conformational Studies of Histones

Histone-DNA Interactions: Thermal Denaturation Studies

Histone-DNA Interactions: Circular Dichroism Studies

Chromatin Subunits

Postsynthetic Modifications of Histone Structure: A Mechanism for the Control of Chromosome Structure by the Modulation of Histone-DNA Interactions

Nuclear Nonhistone Proteins: Chemistry and Function

Regulation of Gene Expression in Chick Oviduct

Low Molecular Weight Nuclear RNA : Size, Structure and Possible Function

The Organization of DNA Sequences in Polytene Chromosomes of Drosophila

Lampbrush Chromosomes