Chondroitin Sulfate, Volume 53

1st Edition

Structure, role and pharmacological activity

Serial Volume Editors: Nicola Volpi
Hardcover ISBN: 9780120329557
eBook ISBN: 9780080471952
Imprint: Academic Press
Published Date: 28th June 2006
Page Count: 600
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Table of Contents


Isolation, purification and analysis of chondroitin sulfate proteoglycans Fumiko Matsui and Atsuhiko Oohira

Isolation and Purification of Chondroitin Sulfate Luiz-Claudio F. Silva

Structure of chondroitin sulfate Fotini N. Lamari and Nikos K. Karamanos

Progress in the structural biology of chondroitin sulfate Barbara Mulloy

The biosynthesis and catabolism of galactosaminoglycans Vikas Prabhakar and Ram Sasisekharan

Biosynthesis of chondroitin sulfate: from the early, precursor discoveries to nowadays, genetic approaches Mauro S.G. Pavao, Ana Christina Vilela-Silva and Paulo A.S. Mourao

Advances in the analysis of chondroitin/dermatan sulfate M. Stylianou, I.-E. Triantaphyllidou and D.H. Vynios

Chondroitin sulfate lyases - their applications in analysis and glycobiotechnology Emmanuel Petit, Cedric Delattre, Dulce Papy-Garcia and Phillipe Michaud

Chondroitin sulfate Lyases: Structure, Activity and Applications in Analysis and the Treatment of Diseases Robert J. Linhardt, Fikri Y Avci, Toshohiko Toida, Yeong Shik Kim and Miroslaw Cygler


Structure, metabolism and tissue roles of chondroitin sulfate proteoglycans Christopher J. Handley, Tom Samiric and Mina Z. Ilic

Emergence and structural characteristics of chondroitin sulfates in the animal kingdom Lucia O. Sampaio and Helena B. Nader

Role of the sulfation pattern of chondroitin sulfate in its biological activities and the binding of growth factors Chilkund


CS is an unbranched, polydisperse, complex glycosaminoglycan extracted and purified from various tissues. This polyanion is interacting with both plasma and cells, it is able to modulate many biochemical and physiologic processes. Due to the presence of sulfate groups in different amounts and located in various positions, CS represents a very heterogeneous family of polysaccharides. therefore, the preparative approach and the analytical techniques are of paramount importance to produce CS with specific structure and properties and of pharmaceutical grade.

Key Features

Includes recent technologies and methodologies to study and understand the structure and properties of chondroitin sulfate (CS) Authoritative contributors from the scientific community with expertise in the field of CS and complex polysaccharides *Detailed and accurate figures to describe and illustrate complex molecular and macromolecular structures and properties


University researchers and students in the field of complex polysaccharides, biomaterials, biochemistry, pharmacology and pathology. Pharmaceutical companies, researchers, and medical doctors/clinicians.


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© Academic Press 2006
Academic Press
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About the Serial Volume Editors

Nicola Volpi Serial Volume Editor

Affiliations and Expertise

University of Modena and Reggio Emilia, Department of Biologia Animale, Modena, Italy