Save up to 30% on Elsevier print and eBooks with free shipping. No promo code needed.
Save up to 30% on print and eBooks.
Cholinergic Ligand Interactions
1st Edition - January 1, 1971
Editors: D. J. Triggle, J.F. Moran, E. A. Barnard
Language: English
eBook ISBN:9781483276564
9 7 8 - 1 - 4 8 3 2 - 7 6 5 6 - 4
Cholinergic Ligand Interactions presents the papers read at a symposium held at the State University of New York at Buffalo, 25-26 May 1970. The recent purification and…Read more
Purchase options
LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Cholinergic Ligand Interactions presents the papers read at a symposium held at the State University of New York at Buffalo, 25-26 May 1970. The recent purification and crystallization of acetylcholinesterase together with real progress in the purification of receptor components indicated the desirability of organizing a symposium to discuss not only these aspects but also the structural bases for cholinergic ligand interaction with these macromolecules, the conformational changes involved with ligand binding, the quantitation of cholinergic ligand binding sites, and the roles of acetylcholinesterase and its isozymes in muscle disease. The volume contains nine chapters and begins with a study on possible conformational changes in acetylcholinesterase. This is followed by separate chapters on the subunits of acetylcholinesterase; in vitro studies with the cholinergic receptor of the eel electroplax; identification and isolation of acetylcholine receptors; assay and properties of essential (junctional) cholinesterases of the rat diaphragm; and structural variations in cholinergic ligands. Subsequent chapters deal with ligand interactions at the muscarinic receptors and changes in cholinesterases isozymes during normal and dystrophic muscle development.
Contributors
Preface
The Possibility of Conformational Changes in Acetylcholinesterase
Studies on the Sub units of Acetylcholinesterase
In Vitro Studies with the Cholinergic Receptor of the Eel Electroplax
Binding of Cholinergic Ligands to Electroplaxes and Brain Tissue
Assay and Properties of Essential (Junctional) Cholinesterases of the Rat Diaphragm
Structural Variations in Cholinergic Ligands
Multiple Ligand Binding Sites at the Cholinergic Receptor
Acetylcholinesterase Isozymes and the Maturation of Normal and Dystrophic Muscle
Cholinesterases at Individual Neuromuscular Junctions
Subject Index
No. of pages: 214
Language: English
Edition: 1
Published: January 1, 1971
Imprint: Academic Press
eBook ISBN: 9781483276564
Read Cholinergic Ligand Interactions on ScienceDirect