Chikungunya - 1st Edition - ISBN: 9780128118658

Chikungunya

1st Edition

Editors: Stephen Higgs Dana Vanlandingham Ann Powers
Paperback ISBN: 9780128118658
Imprint: Academic Press
Published Date: 1st March 2018
Page Count: 352
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Description

Chikungunya is the go-to resource for both historical and current information on this important virus that is rapidly increasing its global range. Epidemics since 2005 have spread from Africa and Asia, and through Europe, and an ongoing epidemic has caused nearly 2 million cases in the Americas. The virus is probably established in South and Central America, permanently leaving millions at risk. It causes severe crippling arthritis, with symptoms lasting for months or years. As no vaccine or treatment is available, there is international interest in the virus, and funding opportunities for research have dramatically increased.

This book contributes significantly to our understanding of this virus, bringing combined knowledge that provides a single, up-to-date source of information.

Key Features

  • Provides a comprehensive collection of the state-of-the-art on CHIKV biology in a go-to reference book
  • Edited by leaders in the field who bring their combined knowledge to provide a single, up-to-date source of information
  • Gives better understanding of the transmission and spread of chikungunya virus, a clear, coherent description of the outcomes of infection (both acute and chronic), its biology, and risk factors
  • Pulls relevant background information to justify projects of many professionals developing vaccines and mosquito vector control approaches

Readership

Academics, including Virologist, Immunologists, Epidemiologists, Geneticists, Vaccinologists. Furthermore, the pharmaceutical industry would be interested in this book. Also, policy makers and centers for disease control would be interested

Table of Contents

1. History of Chikungunya
2. Transmission Cycle 3. Human Diseases
4. Chikv in Africa
5. Chikv in Asia
6. Chikv in Europe
7. Chikv in Americas
8. Chikv Genetics
9. Diagnostics and Laboratory Techniques
10. Animal Models
11. Vaccine Candidates
12. The Future


Details

No. of pages:
352
Language:
English
Copyright:
© Academic Press 2018
Published:
Imprint:
Academic Press
Paperback ISBN:
9780128118658

About the Editor

Stephen Higgs

His research on chikungunya virus (CHIKV) preceded the ongoing epidemics that have recently infected over 1M people in the Americas. His development of patented infectious clones of this CHIKV placed his group at the forefront of research on this virus. They have distributed these research tools to other groups in an effort to better understand the epidemic. They have published over 30 papers on many aspects of chikungunya with collaborators from multiple institutes in different countries.

Affiliations and Expertise

Associate Vice President for Research, Kansas State Univeristy, Research Director, Biosecurity Research Institute (BRI), Peine Professor of Biosecurity, Univeristy Distinguished Professor, Diagnostic Medicine & Pathobiology, Kansas USA.

Dana Vanlandingham

Dr. Vanlandingham’s research is focused on the interactions between arboviruses, the mosquito vectors, and the vertebrate host. Infectious clone technology is used to identify the molecular determinants of infection of alphaviruses, bunyaviruses, and flaviviruses. There are currently four areas of research in her laboratory: 1) Rift Valley fever virus vaccine development; 2) examining vector competence of North American mosquitoes for Japanese encephalitis virus; 3) rationale vaccine design based on characterizing yellow fever virus to identify molecular determinants of infectivity and transmissibility by Ae. aegypti mosquitoes; and 4) assessing CHIKV-mosquito interactions and virus inactivation procedures to ensure blood transfusion safety.

Dana obtained her B.S. and M.S. degrees from Colorado State University and her Ph.D from the Liverpool School of Tropical Medicine in 2006.

Affiliations and Expertise

Assistant Professor, College of Veterinary Medicine, Kansas State University, Manhattan, KS , USA

Ann Powers

Affiliations and Expertise

Chief, Alphavirus Laboratory, Division of Vector Borne Disease, Arboviral Disease Branch, Center for Disease Control and Prevention, Fort Collins, CO, USA