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Chemical Pathways of Metabolism, Volume I focuses on the chemical steps involved in the metabolism of the major constituents of living organisms.
The selection first elaborates on free energy and metabolism, enzymes in metabolic sequences, and glycolysis. Discussions focus on comparative biochemistry of glycolysis, enzymes of the glycolytic cycle, oxidative conversion of glucose to tetrose, transmethylation, and free energy and its determination. The manuscript then examines the tricarboxylic acid cycle and other pathways of carbohydrate metabolism.
The text ponders on the biosynthesis of complex saccharides, including mechanisms of disaccharide formation, syntheses of branched polysaccharides, synthesis of levan from sucrose, and reversibility reactions by hydrolytic enzymes. The publication then elaborates on fat metabolism and acetoacetate formation and sterol and steroid metabolism. Topics include androgens, sterols, phospholipides or phosphatides, path of fat absorption, and theories of fatty acid breakdown and acetoacetate formation.
The selection is a dependable reference for researchers interested in the chemical pathways of metabolism.
Contributors to Volume I
List of Abbreviations and Symbols
1. Free Energy and Metabolism
II. Free Energy and Its Determination
III. Sources of Energy
IV. Release of Energy
2. Enzymes in Metabolic Sequences
II. Cyclophorase-Mitochondrial System
III. The Glycolytic Cycle
IV. Oxidative Conversion of Glucose to Tetrose
V. Synthesis of Glutathione
VII. Energizing of Synthetic Reactions
VIII. Enzymes with More than One Catalytic Function
IX. Experimental Approaches to the Reconstruction of Metabolic Sequences
III. Enzymes of the Glycolytic Cycle
IV. Reversal of Glycolysis
V. Factors Influencing Glycolysis
VI. Comparative Biochemistry of Glycolysis
4. The Tricarboxylic Acid Cycle
II. The Cycle in Animal Tissues
III. The Cycle in Microorganisms
IV. The Cycle in Plant Material
V. The Nature of "Active Acetic Acid VI. Formation of Acetyl Coenzyme A
VII. The Free Energy Changes Associated with the Individual Steps of the Cycle
VIII. Oxidative Phosphorylation
5. Other Pathways of Carbohydrate Metabolism
I. The Metabolism of Fructose
II. The Metabolism of Galactose
III. The Oxidation of Glucose and Glucose-6-Phosphate
IV. The Metabolism of Gluconate
V. Degradation of 6-Phosphogluconate
VI. The Metabolism of Ribulose-5-Phosphate
VII. The Metabolism of Pentoses
VIII. Other Ketopentoses
IX. The Metabolism of D-Ribose and Desoxyribose
X. Alternate Pathways of Glucose Utilization in Intact Cells
XI. Other Mechanisms of Ribose Formation
XII. The Metabolism of Uronic Acids
XIII. The Metabolism of Hexosamine
6. Biosynthesis of Complex Saccharides
I. Synthesis of Monosaccharides
II. Reversibility Reactions by Hydrolytic Enzymes
III. Mechanisms of Disaccharide Formation
IV. Synthesis of α-Linked Polysaccharides by the Action of Phosphorylase
V. Syntheses of Branched Polysaccharides
VI. Structure of Glycogen and Amylopectin
VII. Synthesis of Starch-Glycogen Type Polysaccharides by Transglucosidases
VIII. Synthesis of Dextran
IX. Synthesis of Levan from Sucrose
X. Synthesis of 1,6-α-Linked Oligosaccharides
XI. Synthesis of Fructosans
XII. Synthesis of Galactose-Containing Saccharides
XIII. Mechanisms of Formation of β-Linked Saccharides
7. Fat Metabolism and Acetoacetate Formation
II. The Application of Labeling Agents in the Study of Lipide Metabolism
III. The Concept of the Dynamic State of Body Fats
IV. Theories of Fatty Acid Breakdown and Acetoacetate Formation
V. Sites of Fatty Acid Oxidation
VI. Oxidation of Fatty Acids by the Whole Animal
VII. Intermediary Metabolism
VIII. Phospholipides or Phosphatides
IX. The Path of Fat Absorption
8. Sterol and Steroid Metabolism
II. Adrenocortical Hormones
- No. of pages:
- © Academic Press 1954
- 1st January 1954
- Academic Press
- eBook ISBN:
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