Characterization of Polymeric Biomaterials

Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants.

With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications.

• Presents a self-contained reference on the characterization of polymeric biomaterials
• Provides comprehensive information on how to characterize biomedical polymers in order to improve design and synthesis
• Includes useful case studies that demonstrate the characterization of biomaterial implants

Biomaterials scientists, chemical scientists and engineers in the applied areas of biomaterial science, tissue engineering, drug delivery and regenerative medicine.

Part 1: Characterization of Morphology of Polymeric Biomaterials
1. Characterization of 2D polymeric biomaterial structures or Surfaces
Francesca Brunella, Andrea Serafini and Maria Cristina Tanzi, Politecnico di Milano, Italy
2. Characterization of 3D porous structures
Havard Jostein Haugen, Oslo University, Norway and Serena Bertoldi, Politecnico di Milano, Italy

Part 2: Surface characterization
3. Wettability and contact angle of polymeric biomaterials
Garima Agrawal, Yuvraj Singh Negi, Saharanpur Campus, Uttar Pradesh; Sanghamitra Pradhan, Siksha’O’Anusandhan, University; Mamoni Dash, National Institute of Science Education and Research, Bhubaneswar, and  Sangram K. Samal, Indian Institute of Science, Bangalore, India
4. Spectroscopy (XPS, SIMS, TOF-SIMS) and energy Dispersive Spectroscopy for polymeric biomaterials
L'Hocine Yahia and Karina Mireless, École Polytechnique de Montréal, Montréal, Canada

Part 3: Structure analysis
5. Molecular weight of polymers used in biomedical applications
Oana Maria Dragostin, University “Dunarea de Jos”, Galati and Lenuța Profire, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania
6. Characterization of thermal and cristallinity properties of polymer biomaterials
Giuseppe Tieghi and Maria Cristina Tanzi, Politecnico di Milano, Italy
7. NMR, FT-IR and Raman characterization of polymer biomaterials
Sangram Keshari Samal, Indian Institute of Science, Bangalore, India

Part 4: Mechanical properties
8. Static and uniaxial characterization of polymer biomaterials
Lorenza Draghi, Politecnico di Milano, Italy
9. Dynamico-mechanical characterization of polymer biomaterials
Luigi De Nardo and Silvia Farè, Politecnico di Milano, Italy
10. Rheometry of polymer bionaterials
Assunta Borzacchiello and Francesca Della Sala, IPCB-CNR; Luigi Ambrosio, DCSMT- CNR, Napoli, Italy 
11. Surface mechanical properties of biomaterials
Dariusz Jarząbek and Marcin Michalowski, Institute of Fundamental Technological Research,Warsaw, Poland

Part 5: Biological characterization
12. In vitro interaction of polymeric biomaterials with cells (static)
Aureliana Sousa, Sara C. Neves, Inês C. Gonçalves and Cristina C. Barrias, i3S, INEB and ICBAS, University of Porto, Portugal
13. Interaction of polymeric biomaterials with Bacteria (static)
Elisa Giupponi and Gabriele Candiani, Politecnico di Milano, Italy
14. In vitro dynamic interactions of polymeric biomaterials (elementary)
Sara Mantero, Stefania Adele Riboldi and Serena Bertoldi, Politecnico di Milano, Italy

Part 6: Case studies
15. Traditional” polymer medical devices: ex vivo analysis
Lina Altomare and Silvia Farè, Politecnico di Milano, Italy
16. Collagen hydrogel-based scaffolds for vascular vessel regeneration: mechanical and viscoelastic characterization
Diego Mantovani, Sébastien Meghezi, Laval University, Québec, Canada 
17. Polymer scaffolds for bone regeneration
Masoumeh Meskinfam, Islamic Azad University-Lahijan B