Secure CheckoutPersonal information is secured with SSL technology.
Free ShippingFree global shipping
No minimum order.
Contributor contact details
Woodhead Publishing Series in Textiles
Chapter 1: Microscopy techniques for analyzing the phase nature and morphology of biomaterials
1 Introduction: basic imaging concepts
1.2 Image perception and interpretation
1.3 Light microscopy
1.4 Laser scanning confocal microscopy (LSCM)
1.5 Scanning electron microscopy (SEM)
1.6 Atomic force microscopy (AFM)
Chapter 2: Scattering techniques for structural analysis of biomaterials
2.2 Light scattering
2.3 Wide-angle X-ray diffraction
2.4 Measuring orientation using X-ray diffraction
2.5 Small-angle scattering techniques
2.6 Small-angle X-ray scattering (SAXS)
2.7 Small-angle neutron scattering (SANS)
Chapter 3: Quantitative assays for measuring cell adhesion and motility in biomaterials
3.2 Cell attachment assays
3.3 Cell adhesion strength
3.4 Collective motility of cell populations
3.5 Individual cell motility
3.6 Conclusion and future trends
Chapter 4: Assays for determining cell differentiation in biomaterials
4.2 Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) assays
4.3 Protein and chemical assays
4.4 Imaging assays
4.5 Future trends
Chapter 5: Bioreactors for evaluating cell infiltration and tissue formation in biomaterials
5.2 Bioreactor designs
5.3 Evaluation of cell infiltration and cell seeding
5.4 Evaluation of tissue formation
5.5 Importance of computational fluid mechanics in modeling, imaging, and simulation of the bioreactors
5.6 Failure of bioreactors
5.7 Future trends
5.9 Sources of further information and advice
Chapter 6: Studying molecular-scale proteinâ€“surface interactions in biomaterials
6.1 Introduction: surface-induced thrombosis on artificial surfaces
6.2 Process and changes during protein adsorption
6.3 Factors affecting protein adsorption
6.4 Models of protein adsorption and adsorption isotherms
6.5 Protein adsorption kinetics
6.6 The Vroman effect
6.7 Structure and functions of fibrinogen
6.8 Intermolecular forces and interactions
6.9 Adsorption profile and interfacial kinetics
6.10 Competitive adsorption
6.11 Atomic force microscopy (AFM)
6.12 Interfacial properties of fibrinogen studied by AFM
6.13 Future trends
Chapter 7: Assessing the mutagenic effects of biomaterials: analyzing the cellular genome and abnormalities
7.2 DNA structure
7.3 Genetic mutations
7.4 Cytogenetic mutations
7.5 Types of mutations that can occur at the chromosomal level
7.6 Methods of detection of cytogenetic mutations
7.7 Analyzing genomic organization and variations in genomic copy number
7.8 Copy number variations (CNVs)
7.9 Epigenetic effects on the genome
7.10 Effects of biomaterials on mutagenesis
Chapter 8: Using microarrays to measure cellular changes induced by biomaterials
8.2 What do we measure?
Chapter 9: Standards and methods for assessing the safety and biocompatibility of biomaterials
9.2 Regulatory definition of medical devices
9.3 International Standards Organization (ISO) regulation and guidance
9.4 United States Food and Drug Administration (FDA) regulation and guidance
9.5 Regulation and guidance in Japan and other countries
9.6 Biological tests
9.7 Phasing (timing) of non-clinical testing of medical devices
Biomaterials and medical devices must be rigorously tested in the laboratory before they can be implanted. Testing requires the right analytical techniques. Characterization of biomaterials reviews the latest methods for analyzing the structure, properties and behaviour of biomaterials.
Beginning with an introduction to microscopy techniques for analyzing the phase nature and morphology of biomaterials, Characterization of biomaterials goes on to discuss scattering techniques for structural analysis, quantitative assays for measuring cell adhesion, motility and differentiation, and the evaluation of cell infiltration and tissue formation using bioreactors. Further topics considered include studying molecular-scale protein-surface interactions in biomaterials, analysis of the cellular genome and abnormalities, and the use of microarrays to measure cellular changes induced by biomaterials. Finally, the book concludes by outlining standards and methods for assessing the safety and biocompatibility of biomaterials.
With its distinguished editors and international team of expert contributors, Characterization of biomaterials is an authoritative reference tool for all those involved in the development, production and application of biomaterials.
- Reviews the latest methods for analyzing the structure, properties and behaviour of biomaterials
- Discusses scattering techniques for structural analysis, quantitative assays for measuring cell adhesion, and motility and differentiation
- Examines the evaluation of cell infiltration and tissue formation using bioreactors
Industrial and academic researchers in the biomedical sector
- No. of pages:
- © Woodhead Publishing 2013
- 19th December 2012
- Woodhead Publishing
- Hardcover ISBN:
- Paperback ISBN:
- eBook ISBN:
"...a collection of topics fundamental for the characterization of biomaterials, contributed by the experts in the respective fields...very well-written and useful overview, suitable for specialists as well as researchers new to the field." --Biomat.net, March 2013
"A brief, yet very well-written and useful overview, suitable for specialists as well as researchers new to the field." --Dr. Aleksandr Ovsianikov, The Biomaterials Network.
Professor Michael Jaffe was with Celanese and Hoechst Celanese Research in the USA before leaving for the Biomedical Engineering Department at New Jersey Institute of Technology.
New Jersey Institute of Technology, USA
Willis B. Hammond is a Research Professor in the Department of Biomedical Engineering at NJIT.
Major and Chief MLSO, Royal Army Medical College, Millbank, London, UK
Peter Tolias is Director of the Bio-innovation Program and a Research Professor in the Schaefer School of Engineering and Science at the Stevens Institute of Technology, USA.
University of Medicine and Dentistry New Jersey
Treena Arinzeh is Professor of Biomedical Engineering at NJIT.
New Jersey Institute of Technology, USA
Elsevier.com visitor survey
We are always looking for ways to improve customer experience on Elsevier.com.
We would like to ask you for a moment of your time to fill in a short questionnaire, at the end of your visit.
If you decide to participate, a new browser tab will open so you can complete the survey after you have completed your visit to this website.
Thanks in advance for your time.