Cerebral Vasospasm

1st Edition

Authors: R. Macdonald Bruce Weir
Hardcover ISBN: 9780124641617
eBook ISBN: 9780080528830
Imprint: Academic Press
Published Date: 12th March 2001
Page Count: 518
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Bryce Weir is a high-profile, respected neurologist. Dr. Macdonald is a colleague of Dr. Weir's and is a "rising star" in the field of neurology. This book is the first to cover all aspects of cerebral vasospasm in depth. It takes the reader from the first descriptions of this puzzling and deadly phenomenon to the latest laboratory evidence explaining its pathophysiology. Packed with clinical pearls, it is a must for neurosurgeons, interventional radiologists, neurologists, and neuropathologists.

Key Features

@introbul:Key Features @bul:* Examines the current understanding of vascular smooth muscle physiology

  • Provides in-depth overviews of symptoms and treatments
  • Written by acknowledged experts on the subject
  • Vividly illustrated with beautiful photographs and diagrams
  • Cites over 4,000 key papers on vasospasms
  • Presents key data in an easy-to-use format


Students and researchers in neuroscience and neurology

Table of Contents

Foreword Acknowledgments Abbreviations Chapter 1 History I. Introduction II. Clinical Description III. Pathology IV. Radiology A. Angiography B. Computed Tomography C. Blood Flow Measurements D. Transcranial Doppler V. Medical Aspects A. Hemodynamic Therapy B. Avoidance of Adverse Factors C. Vasodilator and Neuroprotectant Medication VI. Etiology VII. Surgical Aspects A. Clot Removal B. Timing of Surgery C. Angioplasty VIII. Physiology IX. State of the Art X. Farewell Message References Chapter 2 Epidemiology I. Introduction II. Incidence of Subarachnoid Hemorrhage III. Incidence of Vasospasm IV. Timing of Angiography and Incidence of Vasospasm V. Prognostic Factors for Vasospasm A. Blood on CT Scan B. Hypertension C. Anatomical and Systemic Factors D. Clinical Grade E. Antifibrinolytics F. Age and Sex G. Smoking H. Physiological Parameters I. Hydrocephalus VI. Factors Unrelated to Vasospasm VII. Effect of Vasospasm on Outcome VIII. Influence of Surgery on Vasospasm IX. Relative Significance of Vasospasm X. Vasospasm and Cerebral Infarction XI. The Incidence of Vasospasm over Time XII. Vasospasm and Nonaneurysmal Subarachnoid Hemorrhage A. Nonaneurysmal Subarachnoid Hemorrhage B. Arteriovenous Malformations C. Other Causes XIII. Endovascular Coiling and Vasospasm References Chapter 3 Hematology I. Introduction II. Blood A. Cellular Elements B. Plasma C. Erythrocytes D. Endothelial Cells E. Platelets F. Neutrophils G. Mast Cells and Basophils H. Eosinophils I. Monocyte


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© Academic Press 2001
Academic Press
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About the Author

R. Macdonald

Affiliations and Expertise

University of Chicago, Illinois, U.S.A.

Bruce Weir

Affiliations and Expertise

Brain Surgery Research Institute, University of Chicago, Illinois, U.S.A.


"...this is indeed a magnum opus and would play an important factor in finding a remedy for vasospasm...I would add that it is a must read for any neuroscientist currently undertaking research into the subject and indeed would be a valuable background text for any neurosurgeon in training"-JOURNAL OF NEUROLOGY, NEUROSUREGERY,AND PSYCHIATRY (2003) @qu:"Seldom published is a volume as remarkable as Cerebral Vasospasm. ...It provides a comprehensive review of the topic from what seems to me to be every conceivable angle. ...The wisdom of the authors is truly profound and they share it generously with the reader. ...Its in-depth treatment of all aspects of cerebral vasospasm, coupled with a relatively reasonable price, make it a must-have for anybody involved in the investigation, be it clinical or laboratory, of this interesting problem." @source:--Ian B. Ross, University of Neurosurgeons, in the JOURNAL OF NEUROSURGERY (February 2002) @qu:"This book has an easy to follow format and is accessible to those reviewing it as a comprehensive reference. The book will be useful to physiologists, residents, neurologists and neurosurgeons. ...This is a welcome, comprehensive review of the basic clinical aspects of cerebral vasospasm. It will be a standard by which all future books on cerebral vasospasm will be judged. There are no current references like this book." @source&#;Joseph J. Grenier, University of Illinois at Chicago College of Medicine for DOODY'S PUBLISHING (2002) @qu:"...the most complete textbook on this topic. ...This book is an extremely valuable synthesis of information on cerebral vasospasm and cerebral arterial pathophysiology. It is meant not only for neurosurgeons who would like to refresh their general knowledge of the topic, by using this book as a dictionary; it is also suitable for physicians who have less knowledge than specialists about the pathogenesis, prevention, an