Central Cholinergic Systems and Behaviour - 1st Edition - ISBN: 9780122087509, 9780323159555

Central Cholinergic Systems and Behaviour

1st Edition

Authors: F DeFeudis
eBook ISBN: 9780323159555
Imprint: Academic Press
Published Date: 1st January 1974
Page Count: 236
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Central Cholinergic Systems and behavior reviews experimental evidence on the possible involvement of central cholinergic systems in the regulation of animal behavior. More specifically, the book investigates the role of acetylcholine as a transmitter in the mammalian spinal cord and in central nervous function. This text also describes cholinergic involvement in some of the more fundamental processes of central nervous functions and how it may fit into overall cholinergic and non-cholinergic behavioral patterns. This book is organized into seven chapters and begins with an overview of the link between central cholinergic mechanisms and behavior, and then discusses the cholinergic roles in consciousness, emphasizing on the roles of reticular systems in the arousal mechanism. An effort is made to define the cholinergic nature of some spinal mechanisms that are apparently involved in reflexes and posture. An account of the role of cholinergic mechanisms in central respiratory control is also given, along with the function of acetylcholine as an important transmitter at many sites of the central nervous system. The book concludes by analyzing the roles of cholinergic systems in motivated behaviors, emotion, learning, and memory. This book is a valuable resource for students and researchers in fields ranging from physiology to biology and psychiatry.

Table of Contents



Chapter 1 Introduction

Chapter 2 Cholinergic Roles in Consciousness

2.1 Arousal, reticular-activating system

2.2 Sleep-wakefulness: neocortical and limbic activation

2.3 "Dissociation" of EEG and behavior

2.4 Specific sensory systems

2.5 The link between cholinergic and adrenergic arousal

Chapter 3 Cholinergic Roles in Motor Systems

3.1 Posture and reflexes

3.2 Tremors and catalepsy: extrapyramidal system

3.3 Convulsions

3.4 Motor coordination: cerebellar function

3.5 "Circling" behaviors

Chapter 4 Choleringic Roles in Homeostatic Functions

4.1 Respiratory mechanisms

4.2 Cardiovascular mechanisms

4.3 Anti-diuretic hormone (vasopressin) and oxytocin secretion

4.4 Temperature regulation

Chapter 5 Cholinergic Roles in Motivated behaviors, Emotion, Learning and Memory

5.1 Ingestive behaviors

A. Introduction

B. Drinking behavior

C. Feeding behavior

D. Criticism

5.2 Emotion and motivated behaviors

A. Introduction

B. Attack behavior

5.3 Other emotional-motivational behaviors: learning and memory

A. Introduction

B. Roles of the septum and hippocampus

C. Role of the reticular formation

D. Other studies on avoidance behaviors

E. Self-stimulation behavior

F. Possible cholinergic roles in learning and memory

5.4 Environmental effects on cholinergic mechanisms

Chapter 6 Supporting Studies on the Central Release of Acetycholine

6.1 Introduction

6.2 In vivo studies

A. Cerebral cortex

B. Caudate nucleus, thalamus, hypothalamus and mesencephalon

C. Medulla

D. Spinal cord

6.3 In vitro studies

A. Release of ACh from brain slices

B. Release of ACh from subcellular particles

6.4 Validity of collection methods

6.5 The nature of the released substance

Chapter 7 Conclusions


Author Index

Subject Index


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© Academic Press 1974
Academic Press
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About the Author

F DeFeudis

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