Cell Reproduction

In honor of Daniel Mazia

1st Edition - January 1, 1978
Editor: Ellen Dirksen
Language: English
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 1 4 2 9 0 - 8

Cell Reproduction: In Honor of Daniel Mazia represents the proceeding of a symposium entitled “Cell Reproduction” held in Keystone, Colorado, on March 1978. The symposium is… Read more

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Cell Reproduction: In Honor of Daniel Mazia represents the proceeding of a symposium entitled “Cell Reproduction” held in Keystone, Colorado, on March 1978. The symposium is organized to honor Daniel Mazia. Most of the areas of research that are discussed at the conference have their origins in Dan Mazia's laboratory. This volume is divided into nine parts, consisting of papers presented in the symposium. It first focuses on the macromolecular control in cell proliferation and growth, cell cycle regulation, control of genetic expression, and microtubule assembly in vitro and in vivo. In then explains the control of fertilization phenomena, chromosome movement, the mitotic apparatus, and control of cell division and cell cleavage. Lastly, this volume discusses the structural and molecular basis of cell movement and describes the differentiated cell. This book represents a tribute to Daniel Mazia's extraordinary contributions as teacher, scientist, and friend.

Frontispiece

Preface

Acknowledgments

I. Macromolecular Control in Cell Proliferation and Growth

1. Origin of Twoness in Cell Reproduction

2. The Cell Periphery and the Control of Proliferation

3. The Role of RNA Processing in Gene Expression

4. On the Fidelity of DNA Replication

5. Ribosomal Protein Phosphorylation and Control of Cell Growth

6. Biochemical Genetics of Colcemia Sensitivity

7. Ribosomal RNA Synthesis in Early and Late Stage Sea Urchin Embryos as Measured by Its Methylation

II. Cell Cycle Regulation and Control of Growth

8. Relations between Growth and Division during the Cell Cycle

9. Heat-Shock Proteins in Tetrahymena

10. Genetic Analysis of the Cell Life Cycle

11. Selection and Evolution of Yeast Cells in a Chemostat

12. The Clock in Animal Cells Is a Limit Cycle Oscillator

13. A Mortalization Theory for the Control of Cell Proliferation and for the Origin of Immortal Cell Lines

III. Control of Genetic Expression

14. Mitosis and the Programming of Gene Expression

15. Extrachromosomal DNA in Polytene Nuclei of Sarcophaga

16. Genetic Control of RNA Metabolism

17. Control of Sperm Chromatin Structure by Egg Cytoplasm

18. Sea Urchin Hatching Protease: Translation in Blastula of Maternal mRNA

19. Patterns in the Gene Expression during Development of the Sea Urchin Lytechinus pictus

IV. Microtubule Assembly in Vitro and in Vivo

20. Tubulin Assembly in Cultured Cell Extracts

21. Opposite End Assembly and Disassembly of Microtubules: A Steady State Mechanism

22. Evidence of Differences between Tubulins from Mitotic Apparatus, Cilia, and Flagella

23. The Biological Regulation of Microtubule Assembly and Function

24. Tubulin Synthesis in Cell-Free Systems

25. Regulation of Spindle Microtubule Assembly-Disassembly: Localization and Possible Functional Role of Calcium Dependent Regulator Protein

26. Assembly of the Microtubular Organelles, Centrioles, and Cilia

27. Regulation of Flagellar Tubulin Synthesis in Naegleria

28. The Elongation of Cilia and Flagella: A Model Involving Antagonistic Growth Zones

29. Assembly of Sea Urchin Egg Asters in Vitro

V. Control of Fertilization Phenomena

30. Intracellular pH and Activation of the Sea Urchin Egg at Fertilization

31. Macromolecules Mediating Sperm-Egg Recognition and Adhesion during Sea Urchin Fertilization

32. The Block to Polyspermy in the Sea Urchin

33. The Role of External Sodium in Sea Urchin Fertilization

34. Direct Evidence for Ionic Messengers in the Two Phases of Metabolic Derepression at Fertilization in the Sea Urchin Egg

VI. Chromosome Movement and Mitotic Apparatus

35. Induction of Chromosome Motion in the Isolated Mitotic Apparatus as a Function of Microtubules

36. In Vivo Analysis of Mitotic Spindle Dynamics

37. A Possible Microtubule Dependent Mechanism for Mitosis

38. Chromosome Movement in Lysed Cells

39. Advances in Visualization of Mitosis in Vivo

40. Comparative Analysis of Stability Characteristics of Hexylene Glycol and dmso/Glycerol Isolated Mitotic Apparatus

41. Purification and Some Properties of the Mitotic Ca2+-ATPase

42. The "Nuclear Mitotic Apparatus" in Sea Urchin Eggs

43. Conditions for Aldehyde and Osmium Fixation of Sea Urchin Eggs in Mitosis

44. Membranes in the Mitotic Apparatus of Mammalian Cells

VII. Control of Cell Division and Cell Cleavage

45. Control of Cell Division in the Ciliate Stentor

46. The Effect of Emetine on First Cleavage Division in the Sea Urchin, Strongylocentrotus purpuratus Strongylocentrotus purpuratus

47. Sulfhydryl-Disulfide Status and State Transitions in Cells

48. Unequal Division: Its Cause and Significance

49. The Reproduction of Mitotic Centers: New Information on an Old Experiment

50. The Generative Model for Centriole Duplication

51. A Microtubule/Nuclear Envelope Complex

52. Protein Synthesis and Radiation-Induced Mitotic Delay

VIII. Structural and Molecular Basis of Cell Movement

53. Protein Conformation Factors in the Self-Assembly of Cell Ultrastructure

54. Cytoplasmic Actin from Sea Urchin Egg Extracts

55. A Selection Method for Isolating Motility Mutants of Dictyostelium discoideum

56. Formation of Cross-Bridges by Ciliary Dynein Arms

57. Calcium and Sliding Microtubules

IX. The Differentiated Cell

58. Differentiated Gastric Parietal Cells in Culture

59. Hormonal Regulation of Liver Growth

60. The Prereplicative Phase in Differentiated Cells Stimulated to Divide during Regeneration

61. Tissue and Tumor Cell Proliferation