Cell Lineage and Embryo Patterning - 1st Edition - ISBN: 9780123646071, 9780080489155

Cell Lineage and Embryo Patterning, Volume 203

1st Edition

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Serial Volume Editors: Lawrence Etkin
Series Volume Editors: Kwang Jeon
eBook ISBN: 9780080489155
Imprint: Academic Press
Published Date: 4th December 2000
Page Count: 623
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Table of Contents

Specification of the Cell Lineages: Determinants of Cell and Positional Fate in Ascidian Embryos, W.R. Jeffery. RNA Localization and Germ Cell Determination in Xenopus, M. Kloc, S. Bilinski, A. P-Y. Chan, L.H. Allen, N.R. Zearfoss, and L.D. Etkin. Asymmetric Germ Cell Division and Oocyte Determination during Drosophila Oogenesis, W. Deng and H. Lin. The Germline in C. elegans: Origins, Proliferation, and Silencing, G. Seydoux and T. Schedl. Assembly of the Drosophila Germ Plasm, A.P. Mahowald. Early Events in Mammalian Germ Line, R. Anderson, J. Heasman, and C. Wylie.

Patterning of the Embryo: The Initial Phase of Embryonic Patterning in Mammals, R.L. Gardner. Cadherin and Catenins, Wnts and Soxs: Embryonic Patterning in Xenopus, A.L. St. Amand and M.W. Klymkowsky. Establishment of Left-Right Asymmetry, H.J. Yost. Initiation and Early Patterning of the Endoderm, D. Clements, M. Rex, and H.R. Woodland. Neural Patterning in the Vertebrate Embryo, C.R. Altmann and A. Hemmati-Brivanlou. Cell Biology of Limb Patterning, S.A. Schaller, S. Li, V. Ngo-Muller, M.-J. Han, M. Omi, R. Anderson, and K. Muneoka.

Mechanisms to Establish Polarity and Initiate Cell Fate Determination: Defining Cis-Acting Elements and Trans-Acting Factors in RNA Localization, K. Yaniv and J.K. Yisraeli. RNA Localization and Translational Regulation during Axis Specification in the Drosophila Oocyte, R.L. Cooperstock and H.D. Lipshitz. Translational Control in Vertebrate Development, C.H. de Moor and J.D. Richter. Chapter References. Index.


International Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus.

Key Features

Key Features

  • A number of important concepts are discussed, including:
  • How polarity is established during oogenesis
  • How germ cell determinants become organized in the establishment of the germ cell lineage
  • Different strategies used by organisms to establish the germ cell lineage
  • Similarities and differences between the mechanisms used in embryonic patterning
  • The mechanisms and machinery by which molecules such as RNA become asymmetrically segregated
  • The use of similar signaling pathways in patterning of the dorsal-ventral and right-left asymmetries, embryonic germ layers, limb, and nervous system
  • The link between fundamental biological processes such as RNA translation and localization in the regulation of axis specification


Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation, and evolution.


No. of pages:
© Academic Press 2001
4th December 2000
Academic Press
eBook ISBN:


@from:Praise for the Series @qu:"Invaluable reading for all biologists." @source:--NATURE @qu:"In keeping with the high standards set by the editors... carefully prepared and edited in the customary fine format and well-illustrated style of Academic Press publications... this series is a significant contribution to a science that impinges on many fields." @source:--THE QUARTERLY REVIEW OF BIOLOGY @qu:"A valuable addition to any college library as current reference material for advanced undergraduates, graduate students, and professional scientists." @source:--CHOICE @qu:"Maintains the tradition and set-up of the previous volumes and certainly provides up-to-date data on varied aspects of cytology... a valuable acquisition to any library." @source:--THE NUCLEUS @qu:"Should be on the shelf of any biomedical library." @source:--Alvin Tesler, Northwestern Medical School, in DOODY'S

Ratings and Reviews

About the Serial Volume Editors

Lawrence Etkin

Affiliations and Expertise

University of Texas, Graduate School of Biomedical Sciences, Houston, U.S.A.

About the Series Volume Editors

Kwang Jeon

Kwang Jeon

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA