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Cell Fate in Mammalian Development - 1st Edition - ISBN: 9780128042526, 9780128043356

Cell Fate in Mammalian Development, Volume 128

1st Edition

Serial Volume Editors: Berenika Plusa Anna-Katerina Hadjantonakis
Hardcover ISBN: 9780128042526
eBook ISBN: 9780128043356
Imprint: Academic Press
Published Date: 20th February 2018
Page Count: 347
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Table of Contents

1. Introduction
Berenika Plusa and Anna-Katerina Hadjantonakis
2. Cell Polarity-Dependent Regulation of Cell Allocation and the First Lineage Specification in the Preimplantation Mouse Embryo
Deepak Saini and Yojiro Yamanaka
3. Cell Fate Decisions During Preimplantation Mammalian Development
Stephanie Bissiere, Maxime Gasnier, Yanina D. Alvarez and Nicolas Plachta
4. Our First Choice: Cellular and Genetic Underpinnings of Trophectoderm Identity and Differentiation in the Mammalian Embryo
Sergio Menchero, Julio G. Sainz de Aja and Miguel Manzanares
5. Primitive Endoderm Differentiation: From Specification to Epithelialization
Cécilia Bassalert, Lorena V. Estrella and Claire Chazaud
6. The Regulative Nature of Mammalian Embryos
Katarzyna Klimczewska, Anna Kasperczuk and Aneta Suwińska
7. States and Origins of Mammalian Embryonic Pluripotency In Vivo and in a Dish
Priscila Ramos-Ibeas, Jennifer Nichols and Ramiro Alberio
8. Capturing and Interconverting Embryonic Cell Fates in a Dish
Alyson Lokken, Jennifer Watts, Alexandra Moauro and Amy Ralston
9. From Germline to Soma: Epigenetic Dynamics in the Mouse Preimplantation Embryo
Michelle K.Y. Seah and Daniel M. Messerschmidt
10. Pre-gastrula Development of Non-eutherian Mammals
Stephen Frankenberg
11. Pre-implantation Development of Domestic Animals
Anna Piliszek and Zofia E. Madeja
12. Human Pre-gastrulation Development
Sissy E. Wamaitha and Kathy K. Niakan
12. The Mitochondria and the Regulation of Cell Fitness During Early Mammalian Development
Ana Lima, Jörg Burgstaller, Juan M. Sanchez-Nieto and Tristan A. Rodríguez
13. The Head’s Tale: Anterior–Posterior Axis Formation in the Mouse Embryo
Matthew J. Stower and Shankar Srinivas


Cell Fate in Mammalian Development, Volume 128, the latest release in the Current Topics in Developmental Biology series, provides reviews on cell fate in mammalian development. Each chapter is written by an international board of authors, with this release including sections on the Specification of extra-embryonic lineages during mouse pre-implantation development, Cell polarity and fate specification, The circuitry that drives trophectoderm identity, Breaking symmetry and the dynamics of transcription factors directing cell fate specification, Mechanics and cell fate, How physical properties of cells change in development and their effect on cell fate decisions, and more.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Includes new sections on the specification of extra-embryonic lineages during mouse pre-implantation development, cell polarity and fate specification, the circuitry that drives trophectoderm identity, and more
  • Presents the latest release in the Current Topics in Developmental Biology series


Researchers in cell, molecular, developmental and evolutionary biology and in genetics


No. of pages:
© Academic Press 2018
20th February 2018
Academic Press
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Serial Volume Editors

Berenika Plusa

Berenika Plusa

Berenika Plusa RESEARCH POSTS 2007-present: Lab Leader, Lecturer, Faculty of Biology, Medicine and Health, University of Manchester 2006-2007: Visiting Scientist in Anna-Katherina Hadjantonakis lab, Memorial Sloan-Kettering Cancer Centre, New York, USA 2006: Research Associate to Alfonso Martinez-Arias, University of Cambridge, Dept. of Genetics, Cambridge UK 2000-2006: Research Associate to David Glover and Magdalena Zernicka-Goetz, University of Cambridge, Dept. of Genetics and Gurdon CRC/Wellcome Trust Institute, Cambridge UK EDUCATION AND TRAINING 1995-2000 Ph.D. in Animal Science, Polish Academy of Sciences, Institute of Genetics and Animal Breeding, Department of Experimental Embryology, Jastrzebiec, Poland. Supervisor Prof. Jacek A. Modlinski 1993-1995 M.Sc. Biology, Department of Embryology, Faculty of Biology, University of Warsaw, Poland. Supervisor Prof. Andrzej K. Tarkowski. 1990-1995 Studies at University of Warsaw, Faculty of Biology. CURRENT RESEARCH FUNDING 2016-2018 Wellcome Trust PhD Programme in Quantitative and Biophysical Biology, Co PI 2011-2016 (with additional non cost 2 years extension up to 2018) Wellcome Trust equipment grant Co PI with Prof. N Papalopulu, Prof. E. Amaya, Dr K. Dorey, Dr T. Millard; £303 165.0 PAST RESEARCH FUNDING 2014-2016 Co PI on Leverhulme Trust project grant Co PI with Dr. K. Chalut and Dr. J Nichols; amount rewarded for Manchester £111 109.0 2014-2015 Co PI on FLS internal award: Quantitative Biology initiative with Prof. C. Thompson and Dr S. Cotter; £37 957. 2009-2012 PI on BBSRC grant £413 082.93 2007-2012 PI on Manchester Fellowship £368 439.0

Affiliations and Expertise

University of Manchester, UK and Polish Academy of Sciences, Poland

Anna-Katerina Hadjantonakis

Anna-Katerina Hadjantonakis

Anna-Katerina (Kat) Hadjantonakis received a BSc in Biochemistry in 1990, and PhD in Molecular Genetics in 1995, from Imperial College, London. From 1996 to 20013 she undertook postdoctoral studies with Andras Nagy and Janet Rossant at the Samuel Lunenfeld Research Institute, Toronto, and Ginny Papaioannou at Columbia University, New York. In 2004 she established her independent laboratory. She is currently a Member of the Sloan Kettering Institute and a Professor at Cornell University. Kat Hadjantonakis serves on the editorial boards of the journals Development, Developmental Cell, Developmental Biology, BMC Biology, and Genesis. She is the Section Editor in Early Patterning at BMC Developmental Biology, and deputy editor-in-chief at Biology Open. The long-term goal of research in the Hadjantonakis lab is to decipher mechanisms underlying cell lineage specification and tissue morphogenesis. They use the mouse as a predominant experimental mammalian model. They focus on a continuum of events taking place within the mammalian embryo that are bookended by two distinct but interrelated biological processes: blastocyst formation and gastrulation. Quantitative single-cell resolution analyses are a hallmark approach they take.

Affiliations and Expertise

Memorial Sloan-Kettering Cancer Center, NY, USA