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1. Anisotropic cell-derived matrices with controlled 3D architecture
Josep Samitier Martí Sr.
2. Generation of functional fluorescently-labelled cell-derived matrices by means of genetically-modified fibroblasts
3. Bi-layered cell-derived matrices
4. Engineering clinically-relevant cell-derived matrices using primary fibroblasts
5. Decellularized matrices for bioprinting applications
6. Cell-derived matrices for tumor cell modelling
7. Implementation of a basement membrane invasion assay using mesenteric tissue
Armando del Rio Hernandez and Ritobrata Ghose
8. Integration of cell-derived matrices in microfluidic devices
9. Characterization of the mechanical properties of CDMs by atomic force microscopy
10. Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices
11. Molecular characterization of cell-derived matrices
12. A human bone-derived 3D scaffold for studying MSC interactions within the skeletal niche
13. Macromolecular crowding in cell culture
Dimitrios I. Zeugolis
Cell-derived Matrices, Part A, Volume 156, provides a detailed description and step-by-step methods surrounding the use of three-dimensional cell-derived matrices for tissue engineering applications. Biochemical, biophysical and cell biological approaches are presented, along with sample results. Specific chapters cover Anisotropic cell-derived matrices with controlled 3D architecture, Generation of functional fluorescently-labelled cell-derived matrices by means of genetically-modified fibroblasts, Bi-layered cell-derived matrices, Engineering clinically-relevant cell-derived matrices using primary fibroblasts, Decellularized matrices for bioprinting applications, and much more.
- Contains contributions from leading experts in the field from across the globe
- Covers a wide array of topics on the use of cell-derived matrices for tissue engineering and regenerative medicine applications
- Includes relevant, analysis-based topics, such as quantification of the mechanical properties, decellularization protocols, and innovative matrix engineering methods
Postgraduates and researchers in the area of tissue engineering, biophysics and cellular biology, and other related scientific areas
- © Academic Press 2020
- 1st April 2020
- Academic Press
- Hardcover ISBN:
Dr. David Caballero is a senior Research Associate at the 3B’s Research Group, I3Bs – Institute for Biomaterials, Biodegradables and Biomimetics at University of Minho (Portugal). Dr. Caballero has broad experience in the fields of biophysics, bioengineering, microfluidics, and nanotechnology. His main research interests include the development of novel bioengineered in vitro models to study the mechanistic determinants of cancer cell invasion. Currently, Dr. Caballero work focuses in the development of innovative multi-organ-on-chip tumor models using engineered native-like 3D biomaterials for drug screening applications.
Senior Research Associate, 3B’s Research Group, I3Bs – Institute for Biomaterials, Biodegradables and Biomimetics, University of Minho, Portugal
Prof. Subhas C Kundu is a European Research Area Chair and Professor at the 3B´s Research Group, I3Bs – Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho (Portugal). Earlier Prof. Kundu was a Professor in the Department of Biotechnology at the Indian Institute of Technology Kharagpur (India). He obtained his post-graduation and PhD in Genetics from Banaras Hindu University (India) and received his post-doctoral trainings at the Institute of Molecular Biology in Moscow, the York University in Canada, the Medical University in Lubeck (Germany), and the Brunel University in UK. His research interests include silk biomaterial matrices for biomedical applications including 3D cancer modelling for investigating tumor growth and progression. His present area of interest is the use of natural-based biomaterials for 3D cancer modelling and drug screening.
European Research Area Chair and Professor, 3B´s Research Group, I3Bs – Institute on Biomaterials, Biodegradables and Biomimetics of University of Minho, Portugal
Prof. Rui L Reis is the Vice-President for Research and Innovation of University of Minho (Portugal), Director of the 3B’s Research Group, I3Bs – Institute for Biomaterials, Biodegradables and Biomimetics, and Director of ICVS/3B´s Associate Laboratory, both at University of Minho (Portugal). He is also the CEO of the European Institute of TERM, the Coordinator of Discoveries Centre for Regenerative and Precision Medicine, and the Global Past-President of Tissue Engineering and Regenerative Medicine International Society (TERMIS). He is a recognized world expert in the TERM and biomaterials fields, has edited several books and has more 1200 publications and around 70 patents. He co-founded several companies that raised private investments. He has been awarded several important international prizes, including among others the Jean Leray and George Winter Awards (ESB), the Clemson Award (SFB) and TERMIS-EU Awards (i) for contributions to the literature and (ii) the lifetime achievement, and recently the UNESCO- International Life Sciences Award and the IET A. F. Harvey Engineering Research Prize.
3B's Research Group, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine