Cell Biology - 2nd Edition - ISBN: 9780808923527, 9780323278874

Cell Biology

2nd Edition

With STUDENT CONSULT Access

Authors: Thomas Pollard William Earnshaw Jennifer Lippincott-Schwartz Thomas Pollard William Earnshaw Jennifer Lippincott-Schwartz
eBook ISBN: 9780323278874
eBook ISBN: 9781437700633
eBook ISBN: 9780323265188
Hardcover ISBN: 9781416022558
Imprint: Saunders
Published Date: 18th April 2007
Page Count: 928
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Description

A masterful introduction to the cell biology that you need to know! This critically acclaimed textbook offers you a modern and unique approach to the study of cell biology. It emphasizes that cellular structure, function, and dysfunction ultimately result from specific macromolecular interactions. You'll progress from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. The exquisite art program helps you to better visualize molecular structures.

Key Features

  • Covers essential concepts in a more efficient, reader-friendly manner than most other texts on this subject.
  • Makes cell biology easier to understand by demonstrating how cellular structure, function, and dysfunction result from specific macromole¬cular interactions.
  • Progresses logically from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states.
  • Helps you to visualize molecular structures and functions with over 1500 remarkable full-color illustrations that present physical structures to scale.
  • Explains how molecular and cellular structures evolved in different organisms.
  • Shows how molecular changes lead to the development of diseases through numerous Clinical Examples throughout.
  • Includes STUDENT CONSULT access at no additional charge, enabling you to consult the textbook online, anywhere you go · perform quick searches · add your own notes and bookmarks · follow Integration Links to related bonus content from other STUDENT CONSULT titles—to help you see the connections between diverse disciplines · test your knowledge with multiple-choice review questions · and more!

Table of Contents

SECTION I: Introduction to Cell Biology

CHAPTER 1
Introduction to Cells
CHAPTER 2
Evolution of Life on Earth

SECTION II: Chemical and Physical Background

CHAPTER 3
Molecules: Structures and Dynamics
CHAPTER 4
Biophysical Principles
CHAPTER 5
Macromolecular Assembly
CHAPTER 6
Research Strategies

SECTION III: Membrane Structure and Function

CHAPTER 7
Membrane Structure and Dynamics
CHAPTER 8
Membrane Pumps
CHAPTER 9
Membrane Carriers
CHAPTER 10
Membrane Channels
CHAPTER 11
Membrane Physiology

SECTION IV: Chromatin, Chromosomes, and the Cell Nucleus

CHAPTER 12
Chromosome Organization
CHAPTER 13
DNA Packaging in Chromatin and Chromosomes
CHAPTER 14
Nuclear Structure and Dynamics

SECTION V: Central Dogma: From Gene to Protein

CHAPTER 15
Gene Expression
This chapter was written by Jeffrey L. Corden
CHAPTER 16
Eukaryotic RNA Processing
This chapter was written by David Tollervey
CHAPTER 17
Protein Synthesis and Folding

SECTION VI: Cellular Organelles and Membrane Trafficking

CHAPTER 18
Posttranslational Targeting of Proteins
CHAPTER 19
Mitochondria, Chloroplasts, Peroxisomes
CHAPTER 20
Endoplasmic Reticulum
CHAPTER 21
Secretory Membrane System and Golgi Apparatus CHAPTER 22
Endocytosis and the Endosomal Membrane System CHAPTER 23
Degradation of Cellular Components
SECTION VII
Signaling Mechanisms
CHAPTER 24
Plasma Membrane Receptors
CHAPTER 25
Protein Hardware for Signaling
CHAPTER 26
Second Messengers
CHAPTER 27
Integration of Signals

SECTION VIII: Cellular Adhesion and the Extracellular Matrix

CHAPTER 28
Cells of the Extracellular Matrix and Immune System
CHAPTER 29
Extracelluar Matrix Molecules
CHAPTER 30
Cellular Adhesion
CHAPTER 31
Intercellular Junctions
CHAPTER 32
Connective Tissues

SECTION IX: Cytoskeleton and Cellular Motility

CHAPTER 33
Actin and Actin-Binding Proteins
CHAPTER 34
Microtubules and Centrosomes
CHAPTER 35
Intermediate Filaments
CHAPTER 36
Motor Proteins
CHAPTER 37
Intracellular Motility
CHAPTER 38
Cellular Motility
CHAPTER 39
Muscles

SECTION X: Cell Cycle

CHAPTER 40
Introduction to the Cell Cycle
CHAPTER 41
G1 Phase and Regulation of Cell Proliferation
CHAPTER 42
S Phase and DNA Replication
CHAPTER 43
G2 Phase and Control of Entry into Mitosis
CHAPTER 44
Mitosis and Cytokinesis
CHAPTER 45
Meiosis
CHAPTER 46
Programmed Cell Death

Glossary
Index

Details

No. of pages:
928
Language:
English
Copyright:
© Saunders 2007
Published:
Imprint:
Saunders
eBook ISBN:
9780323278874
eBook ISBN:
9781437700633
eBook ISBN:
9780323265188
Hardcover ISBN:
9781416022558

About the Author

Thomas Pollard

Affiliations and Expertise

Sterling Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT

William Earnshaw

Affiliations and Expertise

Professor and Wellcome Trust Principal Research Fellow, Wellcome Trust Centre for Cell Biology, ICB, University of Edinburgh, Scotland, United Kingdom

Jennifer Lippincott-Schwartz

Affiliations and Expertise

Group Leader, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia, United States

Thomas Pollard

Affiliations and Expertise

Sterling Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT

William Earnshaw

Affiliations and Expertise

Professor and Wellcome Trust Principal Research Fellow, Wellcome Trust Centre for Cell Biology, ICB, University of Edinburgh, Scotland, United Kingdom

Jennifer Lippincott-Schwartz

Affiliations and Expertise

Group Leader, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia, United States