Cell Biology

Cell Biology

First published on February 3, 2023

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  • Authors: Thomas Pollard, William Earnshaw, Jennifer Lippincott-Schwartz, Graham Johnson
  • Paperback ISBN: 9780323758017
  • Hardcover ISBN: 9780323758000

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Description

Accessible and user-friendly, Cell Biology, 4th Edition, provides a strong foundation for students entering health care career paths as well as higher level research areas. Clear, readable text and high-quality, detailed illustrations help readers quickly grasp challenging content—all focusing on cellular processes without delving into molecular processes. Drs. Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, and author/illustrator Dr. Graham Johnson have thoroughly updated this popular text to ensure its relevance for students in biology, biotechnology, medicine, and pathophysiology, covering key principles of cellular function and explaining how molecular defects lead to cellular dysfunction and cause human disease.

Table of Contents

  • Front Matter/Back Matter/Section Openers
    1 Introduction to Cells
    2 Evolution of Life on Earth
    3 Molecules: Structures and Dynamics
    4 Biophysical Principles
    5 Macromolecular Assembly
    6 Research Strategies
    7 Chromosome Organization
    8 DNA Packaging in Chromatin and Chromosomes
    9 Nuclear Structure and Dynamics
    10 Gene Expression
    11 Eukaryotic RNA Processing
    12 Protein Synthesis and Folding
    13 Membrane Structure and Dynamics
    14 Membrane Pumps
    15 Membrane Carriers
    16 Membrane Channels
    17 Membrane Physiology
    18 Posttranslational Targeting of Proteins
    19 Mitochondria, Chloroplasts, Peroxisomes
    20 Endoplasmic Reticulum
    21 Mechanisms of Vesicular Trafficking
    22 Secretory Membrane System and Golgi Appartus
    23 Endocytosis and Endosomal Membrane System
    24 Processing and Degradation of Cellular Components
    25 Plasma Membrane Receptors
    26 Protein Hardware for Signaling
    27 Second Messengers
    28 Integration of Signals
    29 Cells of the Extracellular Matrix and Immune System
    30 Extracellular Matrix Molecules
    31 Cellular Adhesion
    32 Intercellular Junctions
    33 Connective Tissues
    34 Actin and Actin-Binding Proteins
    35 Microtubules and Centrosomes
    36 Intermediate Filaments
    37 Motor Proteins
    38 Intracellular Motility
    39 Cellular Motility
    40 Muscles
    41 Introduction to the Cell Cycle
    42 G1 Phase and Regulation of Cell Proliferation
    43 S Phase and DNA Replications
    44 G2 Phase, Responses to DNA Damage, and Control of Entry into Mitosis
    45 Mitosis
    46 Cytokinesis
    47 Meiosis
    48 Programmed Cell Death
     Cell SnapShots

Product details

  • No. of pages: 918
  • Language: English
  • Copyright: © Elsevier 2023
  • Published: February 3, 2023
  • Imprint: Elsevier
  • Paperback ISBN: 9780323758017
  • Hardcover ISBN: 9780323758000

About the Authors

Thomas Pollard

Thomas Dean Pollard is a prominent educator, cell biologist and biophysicist whose research focuses on understanding cell motility through the study of actin filaments and myosin motors. He is Sterling Professor of Molecular, Cellular & Developmental Biology and a Professor of Cell Biology and Molecular Biophysics & Biochemistry at Yale University. He was Dean of Yale's Graduate School of Arts and Sciences from 2010 to 2014, and President of the Salk Institute for Biological Studies from 1996 to 2001. Pollard is very active in promoting scientific education and research primarily through two major societies, both of which he is a past President: the American Society for Cell Biology and the Biophysical Society

Affiliations and Expertise

Sterling Professor, Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT

William Earnshaw

William Charles Earnshaw is Professor of Chromosome Dynamics at the University of Edinburgh where he has been a Wellcome Trust Principal Research Fellow since 1996. Earnshaw is an elected Fellow of the Royal Society since 2013 for his studies of mitotic chromosome structure and segregation. Before Edinburgh, he was Professor of Cell Biology and Anatomy at Johns Hopkins School of Medicine.

Affiliations and Expertise

Professor and Wellcome Trust Principal Research Fellow, Wellcome Trust Centre for Cell Biology, ICB, University of Edinburgh, Scotland, United Kingdom

Jennifer Lippincott-Schwartz

Jennifer Lippincott-Swartz is Group Leader at the Howard Hughes Medical Institute Janelia Research Campus. Her lab uses live cell imaging approaches to analyze the spatio-temporal behaviour and dynamic interactions of molecules in cells with a special focus on neurobiology. Before Janelia, Lippincott-Swartz was a primary investigator and chief of the Section on Organelle Biology in the Cell Biology and Metabolism Branch. Her work there included a collaboration with physicists Eric Betzig and Harald Hess (now group leaders at Janelia), who proposed a new function for the photoactivatable protein. The scientists used the protein to generate photoactivatable fluorophores, or dyes, which enabled them to illuminate different sets of molecules sequentially, creating a microscope image far more detailed than previously possible. The method, called super-resolution microscopy, garnered Betzig the 2014 Nobel Prize in Chemistry.

Affiliations and Expertise

Group Leader, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia, United States

Graham Johnson

Graham Johnson is a computational biologist and Certified Medical Illustrator (CMI) with approx. 20 years of professional experience. He is Director of the Animated Cell at the Allen Institute. Before the Allen Institute, Johnson’s lab in the California Institute for Quantitative Biosciences at the University of California, San Francisco worked to generate, simulate and visualize molecular models of cells. His lab’s Mesoscope project and his team at Allen Institute continue this mission by uniting biologists, programmers and artists to interoperate the computational tools of science and art.

Affiliations and Expertise

Director, Animated Cell, Allen Institute for Cell Biology, Seattle, Washington;, QB3 Faculty Fellow, University of California, San Francisco, San Francisco, California

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