Description

This volume brings together contributors from several different fields of cell biology, physiology, and molecular biology. The common thread that runs through all of the work presented is that cell processes regulate the activities of membrane transport proteins and classes of membrane transport proteins participate in a number of critical cell phenomena. This volume is unique in covering three different members of the ATP Binding Cassette family (MDR, CFTR and STE6) in one place, as well as in including structure and function analysis of the sodium pump in the same forum where its cell biology is considered. The book will appeal to a broad range of biologists with interests in membrane transport, membrane biology, cell biology, and sorting.

Readership

Cell biologists, biochemists, molecular biologists, biophysicists, oncologists, immunologists, nephrologists, endocrinologists, and all graduate students and advanced researchers with an interest in membrane transport and biology, and sorting.

Table of Contents

The Multidrug Resistance Family of Transporters: M.M. Gottesman, S. Currier, E. Bruggemann, I. Lelong, W. Stein, and I. Pastan, The Multidrug Transporter: Mechanistic Considerations. K. Kuchler, E.E. Swartzman, and J. Thorner, A Novel Mechanism for Transmembrane Translocation of Peptides: The Saccharomyces cerevisiae STE6 Transporter and Export of the Mating Pheromone a-Factor. Structure-Function Relationships in Ion Pumps: D.M. Fambrough,M.V. Lemas, K. Takeyasu, K.J. Renaud, and E.M. Inman, Structural Requirements for Subunit Assembly of the Na,K-ATPase. C. Canessa, F. Jaisser, J.-D. Horisberger, and B.C. Rossier, Structure-Function Relationship of Na,K-ATPase: The Digitalis Receptor. Sorting of Ion Transport Proteins and the Creation of Polarized Membrane Domains: P.M. Haney and M. Mueckler, Subcellular Targeting and Regulation of Glucose Transporters. Q. Al-Awqati, J. Van Adelsberg, and J. Takito, Plasticity in Epithelial Polarity. W.J. Nelson, Regulation of Cell Adhesion and Development of Epithelial Cell Surface Polarity. C.J. Gottardi, G. Pietrini, M.J. Shiel, and M.J. Caplan, Synthesis and Sorting of Ion Pumps in Polarized Cells. Subject Index.

Details

No. of pages:
172
Language:
English
Copyright:
© 1994
Published:
Imprint:
Academic Press
Print ISBN:
9780121533410
Electronic ISBN:
9780080585123