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Cartilage - 1st Edition - ISBN: 9780123195036, 9781483266909


1st Edition

Biomedical Aspects

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Editor: Brian K. Hall
eBook ISBN: 9781483266909
Imprint: Academic Press
Published Date: 28th May 1983
Page Count: 366
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Cartilage, Volume 3: Biomedical Aspects is a compilation of articles that covers the various aspects of age-related cartilage deterioration, bone disease, and genetic mutation. The book is composed of 10 chapters that highlight different subjects related to the diseases and malformations of cartilage. Relevant topics that are discussed in each chapter include the formation of cartilage outside the confines of the skeleton; aspects of age-related changes in cartilage; tumors that invade cartilage; molecular and biochemical bases of cartilage mutations; and the immunological and bioelectrical properties of cartilage. Physicians, pathologists, orthopedic surgeons, and those working on the human skeletal system will find this text a very good reference material.

Table of Contents




Contents of Other Volumes

1. Ectopic Cartilage, Neoplasia, and Metaplasia

I. Introduction

II. Extraskeletal versus Ectopic Cartilage

III. Specious Ectopic Cartilages

IV. Tumors and Tumor-Like Conditions with Ectopic Cartilage

V. Experimental Ectopic Cartilage

VI. Discussion and Summary


2. Mechanisms of Resorption and Remodeling of Cartilage

I. Introduction

II. Response of Cartilage to Injury

III. Resorption

IV. Remodeling

V Cartilage Transplants

VI. Hormones, Vitamins, and Drugs

VII. Concluding Remarks


3. Lubrication of and by Articular Cartilage

I. Introduction

II. Weeping Lubrication

III. Boundary Lubrication by Synovial Fluid

IV. How Does Synovial Fluid Lubricate?

V. Pathological Synovial Fluids

VI. Lubrication of Soft Tissues

VII. Disputes

VIII. Work in Progress

IX. Summary


4. Aging and Degenerative Diseases Affecting Cartilage

I. Introduction

II. Aging of Extraarticular Cartilages

III. Aging of Joint Cartilage

IV. Degeneration of Articular Cartilage

V. Degenerative Joint Disease

VI. cMiscellaneous Degenerative Disorders of Articular Cartilage

VII. Degenerative Spinal Disease

VIII. Comparative Pathology

IX. Concluding Remarks


5. Tumors of Cartilage

I. Introduction 1

II. Central and Peripheral Benign Lesions

III. Malignant Neoplasms Arising from or Containing Cartilaginous Tissues

IV. Cartilaginous Tumors of Soft Tissue

V. Tumors of Synovial Origin Showing Cartilaginous Differentiation 155

VI. Notochordal and Notochord-Like Tumors

VII. Other Conditions with Cartilaginous Foci, Chondromatous Metaplasia, and Cartilaginous Remnants


6. Mutations Affecting Limb Cartilage

I. Introduction

II. Cartilage

III. Mutations Affecting Limb Cartilage

IV. Analysis of Mutations Affecting Proteoglycan Structure

V. Conclusions


7. Mutations Affecting Craniofacial Cartilage

I. Introduction

II. Central Nervous System Malformations

III. Chondrodysplasias

IV. Craniosynostoses

V. Miscellaneous Disorders

VI. Conclusion


8. Immunology of Cartilage

I. Introduction

II. The Immune Response

III. Antigens in Cartilage

IV. Immunogenicity

V. The Immune Response to Cartilage Grafts

VI. Immunogenicity of Cartilage in Disease States, Especially Rheumatoid Arthritis

VII. The Influence of Immune Responses on Cartilage

VIII. Conclusion


9. Chondrogenesis in Regenerating Systems

I. Introduction

II. Epimorphic versus Tissue Regeneration

III. Fracture Healing

IV Epimorphic Regeneration


10. Bioelectricity and Cartilage

I. Introduction

II. Cartilage in Limb Regeneration

III. Cartilage in Repair of Fractures

IV. Articular Cartilage

V. Oxygen Tension

VI. In Vitro Studies

VII. Demineralized Bone Matrix-Induced Cartilage

VIII. Discussion and Summary




No. of pages:
© Academic Press 1983
28th May 1983
Academic Press
eBook ISBN:

About the Editor

Brian K. Hall

Brian K. Hall

I have been interested in and studying skeletal tissues since my undergraduate days in Australia in the 1960s. Those early studies on the development of secondary cartilage in embryonic birds, first published in 1967, have come full circle with the discovery of secondary cartilage in dinosaurs12. Bird watching really is flying reptile watching. Skeletal tissue development and evolution, the embryonic origins of skeletal tissues (especially those that arise from neural crest cells), and integrating development and evolution in what is now known as evo-devo have been my primary preoccupations over the past 50+ years.

Affiliations and Expertise

Department of Biology, Dalhousie University, Halifax NS Canada

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