Biomedical Aspects

1st Edition - May 28, 1983

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  • Editor: Brian K. Hall
  • eBook ISBN: 9781483266909

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Cartilage, Volume 3: Biomedical Aspects is a compilation of articles that covers the various aspects of age-related cartilage deterioration, bone disease, and genetic mutation. The book is composed of 10 chapters that highlight different subjects related to the diseases and malformations of cartilage. Relevant topics that are discussed in each chapter include the formation of cartilage outside the confines of the skeleton; aspects of age-related changes in cartilage; tumors that invade cartilage; molecular and biochemical bases of cartilage mutations; and the immunological and bioelectrical properties of cartilage. Physicians, pathologists, orthopedic surgeons, and those working on the human skeletal system will find this text a very good reference material.

Table of Contents

  • Contents



    Contents of Other Volumes

    1. Ectopic Cartilage, Neoplasia, and Metaplasia

    I. Introduction

    II. Extraskeletal versus Ectopic Cartilage

    III. Specious Ectopic Cartilages

    IV. Tumors and Tumor-Like Conditions with Ectopic Cartilage

    V. Experimental Ectopic Cartilage

    VI. Discussion and Summary


    2. Mechanisms of Resorption and Remodeling of Cartilage

    I. Introduction

    II. Response of Cartilage to Injury

    III. Resorption

    IV. Remodeling

    V Cartilage Transplants

    VI. Hormones, Vitamins, and Drugs

    VII. Concluding Remarks


    3. Lubrication of and by Articular Cartilage

    I. Introduction

    II. Weeping Lubrication

    III. Boundary Lubrication by Synovial Fluid

    IV. How Does Synovial Fluid Lubricate?

    V. Pathological Synovial Fluids

    VI. Lubrication of Soft Tissues

    VII. Disputes

    VIII. Work in Progress

    IX. Summary


    4. Aging and Degenerative Diseases Affecting Cartilage

    I. Introduction

    II. Aging of Extraarticular Cartilages

    III. Aging of Joint Cartilage

    IV. Degeneration of Articular Cartilage

    V. Degenerative Joint Disease

    VI. cMiscellaneous Degenerative Disorders of Articular Cartilage

    VII. Degenerative Spinal Disease

    VIII. Comparative Pathology

    IX. Concluding Remarks


    5. Tumors of Cartilage

    I. Introduction 1

    II. Central and Peripheral Benign Lesions

    III. Malignant Neoplasms Arising from or Containing Cartilaginous Tissues

    IV. Cartilaginous Tumors of Soft Tissue

    V. Tumors of Synovial Origin Showing Cartilaginous Differentiation 155

    VI. Notochordal and Notochord-Like Tumors

    VII. Other Conditions with Cartilaginous Foci, Chondromatous Metaplasia, and Cartilaginous Remnants


    6. Mutations Affecting Limb Cartilage

    I. Introduction

    II. Cartilage

    III. Mutations Affecting Limb Cartilage

    IV. Analysis of Mutations Affecting Proteoglycan Structure

    V. Conclusions


    7. Mutations Affecting Craniofacial Cartilage

    I. Introduction

    II. Central Nervous System Malformations

    III. Chondrodysplasias

    IV. Craniosynostoses

    V. Miscellaneous Disorders

    VI. Conclusion


    8. Immunology of Cartilage

    I. Introduction

    II. The Immune Response

    III. Antigens in Cartilage

    IV. Immunogenicity

    V. The Immune Response to Cartilage Grafts

    VI. Immunogenicity of Cartilage in Disease States, Especially Rheumatoid Arthritis

    VII. The Influence of Immune Responses on Cartilage

    VIII. Conclusion


    9. Chondrogenesis in Regenerating Systems

    I. Introduction

    II. Epimorphic versus Tissue Regeneration

    III. Fracture Healing

    IV Epimorphic Regeneration


    10. Bioelectricity and Cartilage

    I. Introduction

    II. Cartilage in Limb Regeneration

    III. Cartilage in Repair of Fractures

    IV. Articular Cartilage

    V. Oxygen Tension

    VI. In Vitro Studies

    VII. Demineralized Bone Matrix-Induced Cartilage

    VIII. Discussion and Summary



Product details

  • No. of pages: 366
  • Language: English
  • Copyright: © Academic Press 1983
  • Published: May 28, 1983
  • Imprint: Academic Press
  • eBook ISBN: 9781483266909

About the Editor

Brian K. Hall

Brian K. Hall
I have been interested in and studying skeletal tissues since my undergraduate days in Australia in the 1960s. Those early studies on the development of secondary cartilage in embryonic birds, first published in 1967, have come full circle with the discovery of secondary cartilage in dinosaurs12. Bird watching really is flying reptile watching. Skeletal tissue development and evolution, the embryonic origins of skeletal tissues (especially those that arise from neural crest cells), and integrating development and evolution in what is now known as evo-devo have been my primary preoccupations over the past 50+ years.

Affiliations and Expertise

Department of Biology, Dalhousie University, Halifax NS Canada

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