Key Features

  • Get clear, accurate, and up-to-the-minute coverage of the physiology of the cardiovascular system.

Table of Contents

vii

CON T E N T S

C H A P T E R 1

OVERVIEW OF THE CIRCULATION

AND BLOOD 1

The Circulatory System 1

Blood 5

Erythrocytes 5

Leukocytes 6

Lymphocytes 7

Blood Is Divided into Groups by Antigens

Located on Erythrocytes 7

Summary 9

Case 1-1 9

C H A P T E R 2

EXCITATION: THE CARDIAC

ACTION POTENTIAL . 11

Cardiac Action Potentials Consist of Several

Phases 11

The Principal Types of Cardiac Action

Potentials Are the Slow and Fast

Types 12

Ionic Basis of the Resting

Potential 13

The Fast Response Depends Mainly on

Voltage-Dependent Sodium

Channels 15

Ionic Basis of the Slow Response 24

Conduction in Cardiac Fibers Depends on

Local Circuit Currents 25

Conduction of the Fast Response 25

Conduction of the Slow Response 27

Cardiac Excitability Depends on the

Activation and Inactivation of Specific

Currents 27

Fast Response 27

Slow Response 28

Effects of Cycle Length 28

Summary 29

Case 2-1 29

C H A P T E R 3

AUTOMATICITY: NATURAL

EXCITATION OF THE HEART . 31

The Heart Generates Its Own Pacemaking

Activity 31

Sinoatrial Node 32

Ionic Basis of Automaticity 34

Overdrive Suppression 35

Atrial Conduction 36

Atrioventricular Conduction 37

Ventricular Conduction 39

An Impulse Can Travel Around a Reentry

Loop 41

Afterdepolarizations Lead to Triggered

Activity 42

Early Afterdepolarizations 43

Delayed Afterdepolarizations 43

Electrocardiography Displays the Spread of

Cardiac Excitation 44

Scalar Electrocardiography 44

Dysrhythmias Occur Fr

Details

No. of pages:
304
Language:
English
Copyright:
© 2013
Published:
Imprint:
Mosby
Electronic ISBN:
9780323088268
Electronic ISBN:
9780323279475
Electronic ISBN:
9780323240529
Print ISBN:
9780323086974