Cardiovascular complications of chronic rheumatic diseases, An Issue of Rheumatic Disease Clinics of North America

1st Edition, Volume 49-1 - November 23, 2022
Editors: M. Elaine Husni︎, George A. Karpouzas
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 4 9 2 8 - 9
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 4 9 2 9 - 6

In this issue of Rheumatic Disease Clinics, guest editors Drs. M. Elaine Husni︎ and George A. Karpouzas bring their considerable expert… Read more

Cardiovascular complications of chronic rheumatic diseases, An Issue of Rheumatic Disease Clinics of North America

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In this issue of Rheumatic Disease Clinics, guest editors Drs. M. Elaine Husni︎ and George A. Karpouzas bring their considerable expertise to the topic of Cardiovascular Complications of Chronic Rheumatic Diseases. Top experts in the field cover key topics such as primary and secondary atherosclerotic cardiovascular (ASCVD) risk prevention in the rheumatic disease, pro-thrombotic and pro-atherogenic anti-phospholipid antibodies, recommendations for the use of NSAIDs and CVD risk, and more.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Time Trends of Cardiovascular Disease in the General Population and Inflammatory Arthritis
Key points
Background
Secular trends for the cardiovascular mortality in inflammatory arthritis
Inflammatory arthritis and time trends for risks of atherosclerotic cardiovascular events
Trends for the prognosis after atherosclerotic cardiovascular events
Trends in risk factors for cardiovascular disease
Trends in arrhythmia, valvular heart disease, heart failure, and venous thromboembolism
Discussion
Clinics care points
Funding
Disclosure
Atherosclerotic Cardiovascular Risk Stratification in the Rheumatic Diseases:: An Integrative, Multiparametric Approach
Key points
Introduction
Size of the problem and secular trends
Reasons for differential risk in the inflammatory rheumatic diseases
Cardiovascular risk calculators: Pitfalls and challenges
Biomarkers of atherosclerotic cardiovascular risk in inflammatory rheumatic diseases
Role of artificial intelligence in data synthesis and algorithm crafting
Clinical application and exportability
Unanswered questions/future research addenda
Clinics care points
Disclosure
Funding
Myocardial Involvement in Systemic Autoimmune Rheumatic Diseases
Key points
Introduction
Mechanisms of myocardial involvement in systemic autoimmune rheumatic diseases
Disease-specific implications for myocardial involvement
Summary
Clinics care points
Heart Failure in Rheumatic Disease: Secular Trends and Novel Insights
Key points
Introduction
Summary and perspectives
Clinics care points
Cardiovascular Disease in Large Vessel Vasculitis: Risks, Controversies, and Management Strategies
Key points
Introduction
Takayasu’s arteritis and giant cell arteritis: epidemiology, vascular targets and pathogenesis
Estimates of cardiovascular risk in Takayasu’s arteritis and giant cell arteritis: an overview
Coronary artery disease in Takayasu’s arteritis
Coronary artery disease in giant cell arteritis
Cerebrovascular disease in Takayasu’s arteritis
Cerebrovascular disease in giant cell arteritis
Aortic disease in Takayasu’s arteritis
Aortic disease in giant cell arteritis
Thrombosis in Takayasu’s arteritis (TAK) and giant cell arteritis
Risk factors for cardiovascular diseases in Takayasu’s arteritis (TAK) and giant cell arteritis
Management strategies to minimize cardiovascular diseases in large vessel vasculitides: controversies and practical suggestions
Summary
Clinics care points
Venous Thromboembolism in the Inflammatory Rheumatic Diseases
Key points
Introduction
Summary
Clinics care points
Funding
Lessons from Cardiac and Vascular Biopsies from Patients with and without Inflammatory Rheumatic Diseases
Key points
Disclosures
Summary
Increased cardiovascular risk in inflammatory rheumatic diseases
Feiring heart biopsy study
Vascular inflammation in coronary artery disease and inflammatory rheumatic diseases
Methodological Considerations on Feiring Heart Biopsy Study
Summary
Clinics care points
Role of Lipoprotein Levels and Function in Atherosclerosis Associated with Autoimmune Rheumatic Diseases
Key points
Introduction
Lipid levels and functions in autoimmune rheumatic diseases
Antirheumatic drugs effects on lipoprotein levels and function and impact on atherosclerosis
Clinics care points
Evidence for Biologic Drug Modifying Anti-Rheumatoid Drugs and Association with Cardiovascular Disease Risk Mitigation in Inflammatory Arthritis
Key points
Introduction
TNFα inhibitors
Interleukin-1 and interleukin-6 inhibition
Abatacept
Rituximab
Interleukin-17 and IL12/23 inhibition
Janus kinase inhibitors
Summary
Funding
Compliance with ethical standards
Human and animal rights and informed consent
Clinics care points
Recommendations for the Use of Nonsteroidal Anti-inflammatory Drugs and Cardiovascular Disease Risk: Decades Later, Any New Lessons Learned?
Key points
Introduction
Discussion and recommendations
Clinics care points