Carbohydrates - 1st Edition - ISBN: 9780123120854, 9780080528526

Carbohydrates

1st Edition

Editors: Helen Osborn
Hardcover ISBN: 9780123120854
eBook ISBN: 9780080528526
Imprint: Academic Press
Published Date: 22nd April 2003
Page Count: 452
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Table of Contents

An introduction to carbohydrate synthesis (H.M.I. Osborn). Selective hydroxyl protection and deprotection (J. Robertson, P.M. Stafford). Synthesis and activation of carbohydrate donors : acetates, halides, phenylselenides and glycals ( B.G. Davis et al.). Synthesis and activation of carbohydrate donors : thioglycosides and sulfoxides (K.P.R. Kartha, R.A. Field). Synthesis and activation of carbohydrate donors : acetimidates, n-pentenyl and vinyl glycosides (A.J. Fairbanks, C.M.P. Seward). Modern glycosidation methods: tuning of reactivity (J. Pietruszka). Modern glycosidation methods: orthogonal glycosidation (J. Pietruszka). The stereoselective synthesis of ß-mannosides (S.C. Ennis, H.M.I. Osborn). Synthesis of sialic acid containing carbohydrates (H. Ando et al.). The synthesis of glycosyl amino acids (P.G. Evans et al.). The synthesis of C-linked glycosides (P. Meo, H.M.I. Osborn). The uses of glycoprocessing enzymes in synthesis (B.G. Davis, S.J. Hancock).


Description

An introduction to carbohydrate synthesis (H.M.I. Osborn). Selective hydroxyl protection and deprotection (J. Robertson, P.M. Stafford). Synthesis and activation of carbohydrate donors : acetates, halides, phenylselenides and glycals ( B.G. Davis et al.). Synthesis and activation of carbohydrate donors : thioglycosides and sulfoxides (K.P.R. Kartha, R.A. Field). Synthesis and activation of carbohydrate donors : acetimidates, n-pentenyl and vinyl glycosides (A.J. Fairbanks, C.M.P. Seward). Modern glycosidation methods: tuning of reactivity (J. Pietruszka). Modern glycosidation methods: orthogonal glycosidation (J. Pietruszka). The stereoselective synthesis of ß-mannosides (S.C. Ennis, H.M.I. Osborn). Synthesis of sialic acid containing carbohydrates (H. Ando et al.). The synthesis of glycosyl amino acids (P.G. Evans et al.). The synthesis of C-linked glycosides (P. Meo, H.M.I. Osborn). The uses of glycoprocessing enzymes in synthesis (B.G. Davis, S.J. Hancock).

Key Features

  • The latest volume in the long standing Best Synthetic Methods series

  • Clear chapter by chapter breakdown of carbohydrate synthesis themes with examples of good practical methods for common carbohydrate syntheses.

Readership

For general supplementary reading and as a reference book for use in organic chemistry research laboratories. It is also appropriate as a supplementary text and reference book for university courses and for the practical classes on synthetic organic chemistry.


Details

No. of pages:
452
Language:
English
Copyright:
© Academic Press 2004
Published:
Imprint:
Academic Press
eBook ISBN:
9780080528526
Hardcover ISBN:
9780123120854

Reviews

@qu: "The book certainly belongs in every laboratory dealing with oligosaccharide synthesis. While the critical reader might also long for information on redox processes, inversion of configuration, and chain elongation, undoubtedly, this monograph is a very useful source of practical methods used for the preparation of carbohydrate building blocks and construction of the glycosidic bond. I expect that the book edited by Osborn will become an excellent and timely addition to the bookshelf that already features a comprehensive collection of Methods in Carbohydrate Chemistry, edited by Whistler and Wolfrom/BeMiller of the 1960s and 1970s, and Preparative Carbohydrate Chemistry, edited by Hanessian (1997). Virtually every researcher, ranging from a senior postdoctoral fellow to a very inexperienced undergraduate student just starting to learn this exciting area of organic chemistry, will find a wealth of useful and readily accessible material. The book is highly recommended. " @source: Demchenko, A.V.; Carbohydr. Res. 2005, 340, 173-174.


About the Editors

Helen Osborn Editor

Affiliations and Expertise

Department of Chemistry, University of Reading, Whiteknights, Reading