Cannabinoids and Their Receptors - 1st Edition - ISBN: 9780128121566, 9780128121573

Cannabinoids and Their Receptors, Volume 593

1st Edition

Serial Volume Editors: Patricia Reggio
eBook ISBN: 9780128121573
Hardcover ISBN: 9780128121566
Imprint: Academic Press
Published Date: 26th July 2017
Page Count: 560
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Table of Contents

  1. Mouse Neuroblastoma CB1 Cannabinoid Receptor-Stimulated [35S]GTPɣS Binding: Total and Antibody-Targeted Gα Protein-Specific Scintillation Proximity Assays
    Khalil Eldeeb, Sandra Leone-Kabler and Allyn C. Howlett
  2. Protocols and Good Operating Practices in the Study of Cannabinoid Receptors
    Linda M. Console-Bram, Pingwei Zhao and Mary E. Abood
  3. Real-Time Measurement of Cannabinoid Receptor-Mediated cAMP Signaling
    Morag R. Hunter, David B. Finlay, Christa E. Macdonald, Erin E. Cawston, Natasha L. Grimsey  and Michelle Glass
  4. Techniques for the Cellular and Subcellular Localization of Endocannabinoid Receptors and Enzymes in the Mammalian Brain
    Luigia Cristino, Roberta Imperatore and Vincenzo Di Marzo
  5. Endocannabinoid Transport Proteins: Discovery of Tools to Study Sterol Carrier Protein-2
    Cecilia J. Hillard, Huan Huang, Caleb D. Vogt, Beatriz E. Rodrigues, Terrence S. Neumann, Daniel S. Sem, Friedhelm Schroeder and Christopher W. Cunningham
  6. Lipidomics: A Corrective Lens for Enzyme Myopia
    Heather B. Bradshaw and Emma Leishman
  7. Functional Analysis of Mitochondrial CB1 Cannabinoid Receptors (mtCB1) in the Brain
    Su Melser, Antonio C.P. Zottola, Roman Serrat, Nagore Puente, Pedro Grandes, Giovanni Marsicano and Etienne Hebert-Chatelain
  8. Modeling Neurodegenerative Disorders for Developing Cannabinoid-Based Neuroprotective Therapies
    Javier Fernández-Ruiz, María Gómez-Ruiz, Concepción García, Mariluz Hernández and José A. Ramos
  9. Metabolic Profiling of CB1 Neutral Antagonists
    Herbert H. Seltzman, Rangan Maitra, Katharine Bortoff, Jay Henson, Patricia H. Reggio, Daniel Wesley and Joseph Tam
  10. Ligand-Assisted Protein Structure (LAPS): An Experimental Paradigm for Characterizing Cannabinoid-Receptor Ligand-Binding Domains
    David R. Janero, Anisha Korde and Alexandros Makriyannis
  11. New Methods for the Synthesis of Cannabidiol Derivatives
    Ana Lago-Fernández, Vanessa Redondo, Laura Hernández-Folgado, Laura Figuerola-Asencio and Nadine Jagerovic
  12. Approaches to Assess Biased Signaling at the CB1R Receptor
    Robert B. Laprairie, Edward L. Stahl and Laura M. Bohn
  13. Design and Synthesis of Cannabinoid 1 Receptor (CB1R) Allosteric Modulators: Drug Discovery Applications
    Abhijit R. Kulkarni, Sumanta Garai, David R. Janero and Ganesh A. Thakur
  14. Assessing Allosteric Modulation of CB1 at the Receptor and Cellular Levels
    Caitlin E. Scott and Debra A. Kendall
  15. Purification of Functional CB1 and Analysis by Site-Directed Fluorescence Labeling Methods
    J.F. Fay and D.L. Farrens
  16. Mass Spectrometry Analysis of Human CB2 Cannabinoid Receptor and Its Associated Proteins
    Zhao-Hui Song, Alyssa S. Laun and Jian Cai
  17. Expression and NMR Structural Studies of Isotopically Labeled Cannabinoid Receptor Type II
    Alexei Yeliseev and Klaus Gawrisch
  18. Methods for the Development of In Silico GPCR Models
    Paula Morales, Dow P. Hurst and Patricia H. Reggio
  19. Molecular Dynamics Methodologies for Probing Cannabinoid Ligand/Receptor Interaction
    Diane L. Lynch, Dow P. Hurst, Derek Shore, Mike Pitman and Patricia H. Reggio

Description

Cannabinoids and Their Receptors, Volume 593, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This updated volume includes comprehensive chapters on a variety of topics, including Real time cAMP signaling in response to CB1 activation, CB1 signaling in mitochondria, Lipidomics of cannabinoid systems, Studying endocannabinoid transport, Metabolic profiling of CB1 neutral antagonists, Approaches to assess biased signaling at the CB1 receptor, and the Development of CB1 allosteric modulators.

Key Features

  • Continues the legacy of this premier serial with a new and updated release
  • Covers research cannabinoids and their receptors

Readership

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists


Details

No. of pages:
560
Copyright:
© Academic Press 2017
Published:
Imprint:
Academic Press
eBook ISBN:
9780128121573
Hardcover ISBN:
9780128121566

Reviews

Praise for the Series:
"Should be on the shelves of all libraries in the world as a whole collection." --Chemistry in Industry
"The work most often consulted in the lab." --Enzymologia
"
The Methods in Enzymology series represents the gold-standard." --Neuroscience


About the Serial Volume Editors

Patricia Reggio Serial Volume Editor

Patricia H. Reggio is Marie Foscue Rourk Professsor and Head of the Department of Chemistry and Biochemistry, UNC-Greensboro, Greensboro, USA.

Affiliations and Expertise

Department of Chemistry and Biochemistry, UNC-Greensboro, Greensboro, USA