Cancer Immunotherapy, Volume 90

1st Edition

Authors: James Allison Glen Dranoff
Hardcover ISBN: 9780120224890
eBook ISBN: 9780080463377
Imprint: Academic Press
Published Date: 3rd April 2006
Page Count: 400
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Table of Contents

Engineered cellular vaccines Blockade of T cell checkpoints. Serex in the identification of target antigens New approaches to tumor immunotherapy Melanoma antigens Antibodies and chimeric molecules Tumor Immunosurveillance Dendritic Cells Strategies for Tumor Vaccination DNA vaccines


For some time immunotherapy has been heralded as a breakthrough approach for cancer treatment. Although the potential of this strategy remains solid, the approach needs considerable refinement. Whilst some programmes are looking to increase the understanding of molecular and cellular mechanisms underlying the stimulation of antitumor immunity, others are trying to find the most appropriate clinical setting that will reveal the role of the immune system in combating cancer. Among the most important discoveries have been tumor-specific antigens.

This thematic volume highlights some key issues and discusses where they may move forward. It has been put together by two leading cancer immunotherapists from two eminent institutions that focus on cancer research.


Immunologists, research oncologists, pathologists, and cell biologists


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© Academic Press 2006
Academic Press
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PRAISE FOR THE SERIES: "...among the most active volumes in the libraries of our universities and institutions." -SCIENCE "A provocative and scholarly review of research." -JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

About the Authors

James Allison Author

Affiliations and Expertise

Howard Hughes Medical Institute Memorial Sloan-Kettering Cancer Center, New York, U.S.A.

Glen Dranoff Author

Affiliations and Expertise

Dana-Farber Cancer Institute, Boston, MA, U.S.A.