Description

For some time immunotherapy has been heralded as a breakthrough approach for cancer treatment. Although the potential of this strategy remains solid, the approach needs considerable refinement. Whilst some programmes are looking to increase the understanding of molecular and cellular mechanisms underlying the stimulation of antitumor immunity, others are trying to find the most appropriate clinical setting that will reveal the role of the immune system in combating cancer. Among the most important discoveries have been tumor-specific antigens. This thematic volume highlights some key issues and discusses where they may move forward. It has been put together by two leading cancer immunotherapists from two eminent institutions that focus on cancer research.

Readership

Immunologists, research oncologists, pathologists, and cell biologists

Table of Contents

Engineered cellular vaccines Blockade of T cell checkpoints. Serex in the identification of target antigens New approaches to tumor immunotherapy Melanoma antigens Antibodies and chimeric molecules Tumor Immunosurveillance Dendritic Cells Strategies for Tumor Vaccination DNA vaccines

Details

No. of pages:
400
Language:
English
Copyright:
© 2006
Published:
Imprint:
Academic Press
eBook ISBN:
9780080463377
Print ISBN:
9780120224890
Print ISBN:
9780124111370

About the authors

James Allison

Affiliations and Expertise

Howard Hughes Medical Institute Memorial Sloan-Kettering Cancer Center, New York, U.S.A.

Glen Dranoff

Affiliations and Expertise

Dana-Farber Cancer Institute, Boston, MA, U.S.A.

Reviews

PRAISE FOR THE SERIES: "...among the most active volumes in the libraries of our universities and institutions." -SCIENCE "A provocative and scholarly review of research." -JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION