Calcium And Phosphorus Metabolism - 1st Edition - ISBN: 9780123743503, 9780323158862

Calcium And Phosphorus Metabolism

1st Edition

Authors: James Irving
eBook ISBN: 9780323158862
Imprint: Academic Press
Published Date: 1st January 1973
Page Count: 256
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Calcium and Phosphorus Metabolism focuses on the metabolism of calcium and inorganic phosphorus and covers topics ranging from the mechanism of calcium and phosphorus absorption in the intestine to calcium and phosphorus balances and retention. The results of balance experiments on the intestinal absorption of calcium and phosphorus are also presented. This book is comprised of 15 chapters and begins with an introduction to dietary sources of calcium and phosphorus, including water. The influence of vitamin D on the mechanism of calcium and phosphorus absorption in the intestine is then examined, along with calcium and phosphorus content of the body; recommended daily calcium and phosphorus requirements; calcium and phosphorus in the blood; and bone formation and resorption. The remaining chapters explore the chemical and organic composition of bone, together with theories of mineralization and the action of endocrine glands on bone as well as calcium and phosphorus metabolism. The final chapter is devoted to the metabolism of calcium and phosphorus in the teeth. This monograph will serve as a useful guide for biochemists and physiologists.

Table of Contents


Chapter 1. Dietary Sources of Calcium and Phosphorus

Water as a Source of Calcium

Chapter 2. Mechanism of Calcium and Phosphorus Absorption in the Intestine: The Action of Vitamin D

Vitamin D

Calcium Absorption

Calcium-Binding Protein (CaBP)

Action of Actinomycin D

Enzymes and Calcium Absorption

Phosphorus Absorption

Submicroscopic Location of Vitamin D

Vitamin D Metabolites

Distribution of Vitamin D in the Body

Chapter 3. Intestinal Absorption of Calcium and Phosphorus Data from Balance Experiments


Habituation to Low Calcium Intakes

Other Factors Affecting Calcium Absorption

Absorption of Phosphorus

Chapter 4. Calcium and Phosphorus Content of the Body

Total Calcium

Effects of Dietary Calcium

Placental Transfer of Calcium and Phosphorus

Calcium Content in Humans

Calcium Content in Individual Tissues

Phosphorus Content of the Body

Chapter 5. Calcium and Phosphorus Balances and Retention

Calcium Loss in Sweat

Adaptation to Low Calcium Intakes

Calcium and Phosphorus Studies

Chapter 6. Recommended Daily Calcium and Phosphorus Requirements

Calcium Requirements


Chapter 7. Blood Calcium and Phosphorus

Blood Calcium

Forms of Blood Calcium

Blood Calcium and Egg-Laying

Blood Phosphorus

Homeostasis of Plasma Phosphate

Forms of Phosphorus in the Blood

Nonultrafiltrable Phosphorus

Endocrine Factors and the Blood Calcium and Phosphorus Levels

Dietary Factors and the Blood Calcium and Phosphorus Levels

Chapter 8. Bone Formation and Resorption

Bone Formation

Bone Resorption

Chapter 9. Bone

Chemical Composition of Bone

The Apatite Crystals of Bone

Organic Constituents of Bone

Theories of Mineralization

Chapter 10. Dietary Factors on Bone and Calcium and Phosphorus Metabolism

Protein Uptake and Bone Formation

Vitamin A

Ascorbic Acid

Calcium, Phosphorus, and Vitamin D

Histological Changes in Rickets

Vitamin D

Chapter 11. Action of Endocrine Glands on Bone and Calcium and Phosphorus Metabolism




The Parathyroid Gland

Cyclic AMP




Chapter 12. Calcium and Phosphorus Metabolism of the Teeth



Metabolic Activity of the Teeth

Influence of Factors upon Erupting Teeth

Experimental Dental Caries


Endocrine Glands

Chapter 13. Excretion of Calcium and Phosphorus in the Urine



Magnesium, Calcium, and Phosphorus

Chapter 14. Kinetic and Cybernetic Analysis of Calcium Metabolism


General Approach

Cybernetic Analysis

Concluding Remarks

Chapter 15. Cellular Functions of Calcium

Calcium and Nerve Excitation

Calcium in Neuromuscular and Synaptic Transmission

Calcium and Cellular Extrusion Processes

The Role of Calcium in Muscular Contraction

Calcium and Mitochondria

Other Functions of Calcium and Concluding Remarks


Subject Index


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© Academic Press 1973
Academic Press
eBook ISBN:

About the Author

James Irving

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