Breath Analysis covers technology design, implementing and running measurements; both in the lab and at point of care. This book will help you get up to speed on the state of the art research in this specialized field, and offers guidance on how best to design this technology and conduct breath analysis. This book primarily focuses on the diagnosis of lung cancer, asthma and Chronic Obstructive Pulmonary Diseases. The reliability, consistency and utility of the results you get from breath analysis depends on: exhaled breath sampling procedures and tools; gas sensor array technology (sensing material and transducer); and finally medical pertinence and interpretation. This book discusses all of these factors. The approach of this book is to give a step by step procedure synthesizing the state of the art in a flow-chart with the aim of proposing a common and practical language for breath analysis. This book also discusses best practice solutions for the problems you will face such as sample collection, sensor technology, clinical assessment, medical interpretation, and data analysis.
The research field of breath analysis is intrinsically multidisciplinary, merging know-how, competences and skills pertaining to medicine, electronics, sensors, fluid dynamics, chemistry and statistics. This is the first book to provide an overview of the entire field; currently all the relevant research is scattered across journal articles. The aim of this book is to help find a shared path for researchers involved in breath analysis, through a common technological platform and a shared list of standard operating procedures. Breath Analysis is a practical and functional book about how breath analysis will be brought into the clinical practice. The primary audience is Biomedical Engineers and Medical Doctors, but this could also be a useful book for: hospital technicians, hospital and biomedical SME leading figures, and PhD level Engineering and Medicine
- An overview of existing breath analysis technology with pros and cons
- A tool for mapping, bridging and translation between the different approaches and devices available
- A best practice procedure for exhaled breath collection
Bioengineers, bioengineering and medicine graduate students, electronic engineers, clinical engineers, clinician researchers in respiratory medicine and oncology
- Breathprinting: what, why, how
2. FIRST STEP: Exhaled breath: catch and store: a review of the current methodologies and devices for exhaled breath collection with the aim of integrate them in a standard and shared procedure.
3. SECOND STEP: Breath analysis: two strategies: a brief introduction of the two approaches based on analytical chemistry (spectroscopic) instruments and gas sensor arrays.
4. Sensor systems for breathprinting: a review of the current technologies for exhaled breath analysis using gas sensor arrays with the aim of integrate them in a standard and shared procedure.
5. THIRD STEP: Data analysis
An overview of the gold standard techniques for breathrpinting data analysis oriented to diagnosis.
6. FOURTH STEP: Breathrpinting based diagnosis, selected case study
Each different disease will be presented starting from the consolidated diagnostic technologies in order to define in which way breathprinting can contribute.
- Frail Individuals (COPD, OSAS, CHF)
- Lung cancer
- Breast Cancer
- Pediatric asthma
- Liver diseases
7. FIFTH STEP: Breathprinting roadmap based on expert’s opinion
An interview with experts (also including all the contributors of this ebook).
8. APPENDIX: a review of the current financed projects and initiatives in this field
- No. of pages:
- © Academic Press 2019
- 1st November 2018
- Academic Press
- Paperback ISBN:
Giorgio Pennazza has participated and still participates in numerous national and international projects. He is the author of over 60 publications in journals, book chapters and conference proceedings. He has been teaching in this field for the past 8 years, and his main research interest is in sensors with biomedical applications.
Associate Professor of Electronics, Head of the Unit of Electronics for Sensor Systems, Italy
In 2012 Marco Santonico was a founding member of the company INNOSENSOR Ltd., founded as a spin-off of the University of Rome "Tor Vergata." INNOSENSOR is concerned with the research and development of sensory systems, bio-sensory and their electronic and chemical interfaces. He is the author of over 50 publications in journals, book chapters and proceedings of conferences. He is actively teaching in this field and his main research interest is the development and characterization of sensors and their electronic interfaces for biomedical applications.
Assistant Professor, Universita Campus Bio-Medico di Roma, Unit of Electronics for Sensor Systems, Department of Engineering, Rome, Italy